Biomaterials Science, Год журнала: 2024, Номер unknown
Опубликована: Дек. 23, 2024
This review summarizes the latest advancements in piezoelectric hydrogels and clarifies their wound-dressing applications various types of wounds.
Язык: Английский
Heliyon, Год журнала: 2024, Номер 10(20), С. e38481 - e38481
Опубликована: Сен. 26, 2024
Язык: Английский
Процитировано
6
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0
Materials Chemistry Frontiers, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
A schematic overview of the classification, key properties, and applications piezoelectric antimicrobial polymers.
Язык: Английский
Процитировано
0
Macromolecular Research, Год журнала: 2025, Номер unknown
Опубликована: Фев. 14, 2025
Язык: Английский
Процитировано
0
Advanced Functional Materials, Год журнала: 2025, Номер unknown
Опубликована: Фев. 21, 2025
Abstract Electrical stimulation (ES) dressings have garnered considerable attention owing to their profound impact on chronic wound care, while the existing ES necessitate external power supply or intricate structures, posing potential safety risks and usage inconveniences. Herein, a safe, stable, simple, serviceable, self‐powered (5S) dressing composed of an electrospinning asymmetric nanofiber membrane with screen‐printed electrodes polyurethane foam is developed. The acts as due its electrical double‐layer effect during unidirectional exudate transfer, excellent water absorption retention properties effectively manages exudate. This 5S generates sustained low‐voltage direct current in situ at site creates favorable microenvironment for re‐epithelization. In vitro vivo studies indicate that this can significantly promote healing. Compared control group (on 7th day), collagen deposition treated increased by 15.9%, capillary density 90.6%, epidermal thickness 228.3%, resulting 23.6% enhancement healing rate. Consequently, presents highly sophisticated effective therapeutic approach accelerating
Язык: Английский
Процитировано
0
Advanced Healthcare Materials, Год журнала: 2025, Номер unknown
Опубликована: Март 3, 2025
Abstract Chronic cutaneous wounds are a major clinical challenge worldwide due to delayed healing, recurrent infections, and resistance conventional therapies. Adipose‐derived stem cells (ASCs) have shown promise as cell‐based therapy, but their therapeutic efficacy is often compromised by the harsh microenvironment of chronic wounds. Recent advances in bioengineering, particularly application electrical stimulation (ES), offer an innovative approach enhancing regenerative properties ASCs. By restoring natural current wound, ES provides strong stimulus involved thereby accelerating overall wound‐healing process. studies show that ASCs can be significantly activated ES, which increases viability, proliferation, migration, secretory capacity, all crucial for proper healing This review examines synergistic effects on wound focusing biological mechanisms involved. The also highlights novel self‐powered systems other emerging technologies such advanced conductive materials devices improve translation ES‐based treatments. summarizing state knowledge, this aims provide framework future research care.
Язык: Английский
Процитировано
0
International Journal of Polymer Science, Год журнала: 2025, Номер 2025(1)
Опубликована: Янв. 1, 2025
The performance of drug‐loaded electrospun mats as novel wound dressings is substantially affected by their formulation. In this study, the influence polymer and drug concentration on microstructure, mechanical properties, release behavior well biological characteristics poly(vinylidene fluoride) (PVDF) loaded with Zataria multiflora essential oil (ZMEO) an herbal explored. From microstructural, mechanical, processability viewpoints, blank obtained from solution 14 wt.% PVDF had optimum close to natural extracellular matrix (ECM) human skin. Electrospinning process was hard for solutions more than PVDF. Microstructural defects nanofibers increased, diameter properties decreased ZMEO content. Making electrospinning impossible in presence amount 7 wt.%. 3 5 ZMEO, besides appropriate microstructural showed antioxidant activity 50% antibacterial against both Gram‐negative Gram‐positive bacteria. profile these promising dressing application bimodal. It initially (in 2.5 h) fast so that released range 30%–50%; but then it followed a slow linear pattern time.
Язык: Английский
Процитировано
0
Macromolecular Bioscience, Год журнала: 2025, Номер unknown
Опубликована: Март 25, 2025
With the aging population, fitness issues, poor bone healing, and high infection rates are associated with fractures other diseases. Nevertheless, traditional approaches materials struggle to treat orthopedic diseases by loading exogenous stem cells, growth factors, or merely structurally simulating periosteum. The advancement of biomedical has become critical in addressing challenges tissue regeneration, encompassing a range conditions including wounds, inflammation, infections, fractures, degenerative effects metabolic disorders. Recently, polymer-based piezoelectric have emerged as promising avenue for enhancing regenerative processes. These possess unique electrical properties that can stimulate cellular activities promote making them particularly suitable engineering applications. This review aims delineate multifaceted role treating various bone-related ailments, highlighting their potential active regeneration actively pointing out future research directions medicine engineering. By integrating insights from science develop more effective strategies managing injuries disorders, ultimately promoting osseointegration, accelerating regeneration.
Язык: Английский
Процитировано
0
Advanced Science, Год журнала: 2025, Номер unknown
Опубликована: Апрель 7, 2025
Abstract The incidence and burden of skin wounds, especially chronic complex have a profound impact on healthcare. Effective wound healing strategies require multidisciplinary approach, advances in materials science bioengineering paved the way for development novel dressing. In this context, electrospun nanofibers can mimic architecture natural extracellular matrix provide new opportunities healing. Inspired by bioelectric phenomena human body, nanofibrous scaffolds with electroactive characteristics are gaining widespread attention gradually emerging. To end, review first summarizes basic process healing, causes current status clinical treatment, highlighting urgency importance dressings. Then, biological effects electric fields, preparation materials, manufacturing techniques (EEN) discussed. latest progress EEN enhancing is systematically reviewed, mainly including treatment monitoring. Finally, scaffold to enhance emphasized, challenges prospects summarized.
Язык: Английский
Процитировано
0
Nature Reviews Electrical Engineering, Год журнала: 2025, Номер unknown
Опубликована: Апрель 9, 2025
Язык: Английский
Процитировано
0