Autonomous Anticoagulation on a Biomimetic Al-Based Hierarchical Surface DOI

Libo Tan,

Shengteng Zhao, Zhichao Ma

и другие.

ACS Applied Materials & Interfaces, Год журнала: 2025, Номер unknown

Опубликована: Янв. 21, 2025

Studies targeting the blood repellency and autonomous anticoagulation of superhydrophobic (SH) surfaces are potentially valuable for their application in contact. The abilities potential mechanisms different SH urgently need to be revealed. In this study, a range microprotrusion arrays on Al substrates with varying spacings via laser ablation through utilization organic adsorption siloxane coupling reactions were fabricated. Consequently, gridded Al-based prepared, blood-repellency properties evaluated. vitro experiments demonstrated effectiveness these preventing nonspecific protein platelet adhesion, exhibited no indications hemolysis or toxicity. Remarkably, maintained good antiplatelet adhesion activation inhibition after 7 days incubation platelet-rich plasma, capacity was compared elements analysis surfaces. Specifically, surface low when incubated 10 mg/mL bovine serum albumin solution. Furthermore, study illustrated relationship between hierarchical micronano structure anticoagulant behavior. integration readily available ability represents promising strategy metallic materials medical devices involving

Язык: Английский

Autonomous Anticoagulation on a Biomimetic Al-Based Hierarchical Surface DOI

Libo Tan,

Shengteng Zhao, Zhichao Ma

и другие.

ACS Applied Materials & Interfaces, Год журнала: 2025, Номер unknown

Опубликована: Янв. 21, 2025

Studies targeting the blood repellency and autonomous anticoagulation of superhydrophobic (SH) surfaces are potentially valuable for their application in contact. The abilities potential mechanisms different SH urgently need to be revealed. In this study, a range microprotrusion arrays on Al substrates with varying spacings via laser ablation through utilization organic adsorption siloxane coupling reactions were fabricated. Consequently, gridded Al-based prepared, blood-repellency properties evaluated. vitro experiments demonstrated effectiveness these preventing nonspecific protein platelet adhesion, exhibited no indications hemolysis or toxicity. Remarkably, maintained good antiplatelet adhesion activation inhibition after 7 days incubation platelet-rich plasma, capacity was compared elements analysis surfaces. Specifically, surface low when incubated 10 mg/mL bovine serum albumin solution. Furthermore, study illustrated relationship between hierarchical micronano structure anticoagulant behavior. integration readily available ability represents promising strategy metallic materials medical devices involving

Язык: Английский

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