Schiff Base Mediated Food-Derived Peptide Supramolecular Self-Assembly as Curcumin Carriers DOI

Longjiang Tian,

Xiangyu You, Jingbo Liu

и другие.

Journal of Agricultural and Food Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Дек. 7, 2024

The fusion assembly strategy of supramolecular chemistry combined with dynamic covalent has provided novel insights into the design precision nutrition and intelligent drug delivery carriers. This work involved development a self-assembly originating from entropy- enthalpy-driven bonding on Schiff bases between egg white-derived peptide Gln-Ile-Gly-Leu-Phe (QIGLF) glutaraldehyde (GA), denoted QIGLF–GA. exhibited outstanding characteristics multiwavelength autofluorescence properties. Benefiting potent facilitation interaction base noncovalent force network, QIGLF–GA was afforded an encapsulation capacity curcumin (Cur) more than 22% (≫ 10%) rationally inhibited P-glycoprotein-mediated cellular efflux markedly elevated efficacy Cur in overcoming intestinal epithelial absorption barrier to circulation help endocytosis. Furthermore, QIGLF–GA-Cur features responsive release under weakly acidic conditions, which dramatically contributes intracellular bioavailability Cur.

Язык: Английский

Fructose-modified chitosan-based coassemblies reinforced oral bioavailability of egg white oligopeptides and curcumin via glucose transporter 2-oriented transcytosis and preferable mucus permeation DOI
Jingbo Liu, Yang Liu, Shanglin Li

и другие.

Food Research International, Год журнала: 2025, Номер 206, С. 116065 - 116065

Опубликована: Фев. 24, 2025

Язык: Английский

Процитировано

0

Mixed‐Valence Coordination Strategy Creating Ordered Ternary Ultrasmall Homo‐/Hetero‐structures Driven by Lattice Match for Advanced Photochromism and Encryption Applications DOI Open Access

Yalan Lin,

B.Y. Huang,

Yixie Chen

и другие.

Small, Год журнала: 2025, Номер unknown

Опубликована: Март 13, 2025

Abstract Overcoming the challenges of integrating disparate components in nanoarchitectures, this study introduces a straightforward strategy based on mixed‐valence coordination approach, creating an ordered ternary heterostructure integrated with ultrasmall homojunction. This singular homojunction‐heterostructure unites ultrathin 1D rutile TiO 2 nanowires (NWs) and anatase NWs 0D Prussian Blue Analogs (PBAs) nanoparticles (NPs), all exhibiting crystallographic oriented alignment each other, forming mesocrystals. Experimental theoretical insights disclose that complex interplay between these dissimilar is governed by spontaneous lattice match effect, which not only optimizes but also directs charge transfer, thereby enhancing both efficiency stability. It allows for tailoring valence states Fe within PBA, fine‐tuning composite's photochromic properties, introducing abundant defect structures foster strong interaction oxygen molecules, enabling controllable color‐switching dynamics. Consequently, II 1−x III x ‐PBA/TiO exhibits optimized structure R‐TiO /A‐TiO /PBA, demonstrating exceptional photoelectronic significantly photochromism secure encryption capabilities. These establish solid foundation engineering sophisticated complex‐ordered advancing sustainable energy environmental technologies.

Язык: Английский

Процитировано

0

A platinum(iv)–crocetin nanoplatform with intracellular morphological transformation for enhanced colorectal cancer therapy DOI
Rui Xue,

Zhetong Jin,

Li Lu

и другие.

Journal of Materials Chemistry B, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Pt( iv )–Cro NPs demonstrate concentration-dependent self-assembly and intracellular transformation, enhancing cisplatin's antitumor efficacy against colorectal cancer through boosted cytotoxicity, mitochondrial damage, ROS generation.

Язык: Английский

Процитировано

0

Supramolecular protein-peptide co-assembly mediated by Ca2+ enhances curcumin penetration through intestinal barriers DOI

Longjiang Tian,

Yiheng Zhao,

Fei Pan

и другие.

Food Hydrocolloids, Год журнала: 2025, Номер unknown, С. 111581 - 111581

Опубликована: Май 1, 2025

Язык: Английский

Процитировано

0

Schiff Base Mediated Food-Derived Peptide Supramolecular Self-Assembly as Curcumin Carriers DOI

Longjiang Tian,

Xiangyu You, Jingbo Liu

и другие.

Journal of Agricultural and Food Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Дек. 7, 2024

The fusion assembly strategy of supramolecular chemistry combined with dynamic covalent has provided novel insights into the design precision nutrition and intelligent drug delivery carriers. This work involved development a self-assembly originating from entropy- enthalpy-driven bonding on Schiff bases between egg white-derived peptide Gln-Ile-Gly-Leu-Phe (QIGLF) glutaraldehyde (GA), denoted QIGLF–GA. exhibited outstanding characteristics multiwavelength autofluorescence properties. Benefiting potent facilitation interaction base noncovalent force network, QIGLF–GA was afforded an encapsulation capacity curcumin (Cur) more than 22% (≫ 10%) rationally inhibited P-glycoprotein-mediated cellular efflux markedly elevated efficacy Cur in overcoming intestinal epithelial absorption barrier to circulation help endocytosis. Furthermore, QIGLF–GA-Cur features responsive release under weakly acidic conditions, which dramatically contributes intracellular bioavailability Cur.

Язык: Английский

Процитировано

2