Carrier‐free co‐delivery nanosystem based on prothioconazole and pyrimethanil to enhance fungicidal efficacy and reduce environmental risks DOI
Yulu Liu, Yuqi Huang,

Gaohua Hu

и другие.

Pest Management Science, Год журнала: 2025, Номер unknown

Опубликована: Апрель 17, 2025

The conventional application of fungicides suffers from substantial off-target loss due to photolysis, evaporation, and rain washing, resulting in risks the environment human health. To address these limitations, self-assembled nanopesticides based on two kinds have emerged as precision agrochemical delivery platforms that synchronize enhanced bioactivity with environmental risk mitigation. Herein, core-shell structured nanoparticles (PRO-PYR NPs) an average particle size 263 nm were fabricated prothioconazole (PRO) pyrimethanil (PYR) via non-covalent interactions using co-assembly technology. co-delivery system acid-responsive release property both antifungal activities against Botrytis cinerea Fusarium graminearum duration cinerea. Importantly, obtained PRO-PYR NPs could significantly improve photostability foliage adhesion reduce their volatility leaching potential. Additionally, reduced genotoxicity PRO PYR root tip cells Vicia faba acute toxicity zebrafish. commonly used successfully prepared by technology effectively physicochemical properties. Carrier-free strategy multiple components enhance control effect lower negative impacts associated non-target organisms for integrated pest management. © 2025 Society Chemical Industry.

Язык: Английский

Carrier‐free co‐delivery nanosystem based on prothioconazole and pyrimethanil to enhance fungicidal efficacy and reduce environmental risks DOI
Yulu Liu, Yuqi Huang,

Gaohua Hu

и другие.

Pest Management Science, Год журнала: 2025, Номер unknown

Опубликована: Апрель 17, 2025

The conventional application of fungicides suffers from substantial off-target loss due to photolysis, evaporation, and rain washing, resulting in risks the environment human health. To address these limitations, self-assembled nanopesticides based on two kinds have emerged as precision agrochemical delivery platforms that synchronize enhanced bioactivity with environmental risk mitigation. Herein, core-shell structured nanoparticles (PRO-PYR NPs) an average particle size 263 nm were fabricated prothioconazole (PRO) pyrimethanil (PYR) via non-covalent interactions using co-assembly technology. co-delivery system acid-responsive release property both antifungal activities against Botrytis cinerea Fusarium graminearum duration cinerea. Importantly, obtained PRO-PYR NPs could significantly improve photostability foliage adhesion reduce their volatility leaching potential. Additionally, reduced genotoxicity PRO PYR root tip cells Vicia faba acute toxicity zebrafish. commonly used successfully prepared by technology effectively physicochemical properties. Carrier-free strategy multiple components enhance control effect lower negative impacts associated non-target organisms for integrated pest management. © 2025 Society Chemical Industry.

Язык: Английский

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