Medicine, Год журнала: 2025, Номер 104(5), С. e41393 - e41393

Опубликована: Янв. 31, 2025

Cancer immune evasion is one of the important mechanisms for cancer development, which essential to developing novel immunotherapeutic strategies. The SOX (SRY-related HMG-box) family transcription factors plays a crucial role in normal physiology as well variety human diseases especially cancer. It has been shown that involved processes. This mini-review aimed summarize how members induce by regulating antigen presentation, shaping tumor immunosuppressive milieu, and controlling regulatory checkpoint inhibitors like programmed death ligand 1. Thorough exploration will help uncover mechanism evasion, provide new ideas targets development immunotherapy

Язык: Английский