Prefrontal Cortex Neural Correlates of the Contraction Bias in Frequency Discrimination DOI Creative Commons

Luis Serrano-Fernández,

Manuel Beirán, Ranulfo Romo

и другие.

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2023, Номер unknown

Опубликована: Июль 28, 2023

Abstract Perception is influenced by sensory stimulation, prior knowledge, and contextual cues, which collectively contribute to the emergence of perceptual biases. However, precise neural mechanisms underlying these biases remain poorly understood. This study aims address this gap analyzing recordings from prefrontal cortex (PFC) monkeys performing a vibrotactile frequency discrimination task. Our findings provide empirical evidence supporting hypothesis that can be reflected in activity PFC. We found state-space trajectories PFC neuronal encoded warped representation first presented during Remarkably, distorted aligned with predictions its Bayesian estimator. The identification correlates expands our understanding basis highlights involvement shaping experiences. Similar analyses could employed other delayed comparison tasks various brain regions explore where how reflects different stages trial.

Язык: Английский

Contextual neural dynamics during time perception in the primate ventral premotor cortex DOI Creative Commons
Héctor Díaz,

Lucas Bayones,

M. Álvarez

и другие.

Proceedings of the National Academy of Sciences, Год журнала: 2025, Номер 122(6)

Опубликована: Фев. 6, 2025

Understanding how time perception adapts to cognitive demands remains a significant challenge. In some contexts, the brain encodes categorically (as “long” or “short”), while in others, it precise intervals on continuous scale. Although ventral premotor cortex (VPC) is known for its role complex temporal processes, such as speech, specific involvement estimation underexplored. this study, we investigated VPC processes information during interval comparison task (TICT) and categorization (TCT) primates. We found notable heterogeneity neuronal responses associated with across both tasks. While most neurons responded presentation, smaller subset retained working memory periods. Population-level analysis revealed distinct dynamics between tasks: TICT, population activity exhibited linear parametric relationship duration, whereas TCT, diverged into two corresponding categories. During delay periods, these categorical representations remained consistent within each context. This contextual shift underscores VPC’s adaptive highlights are modulated by demands.

Язык: Английский

Процитировано

1
Representation of a perceptual bias in the prefrontal cortex DOI Creative Commons

Luis Serrano-Fernández,

Manuel Beirán, Ranulfo Romo

и другие.

Proceedings of the National Academy of Sciences, Год журнала: 2024, Номер 121(50)

Опубликована: Дек. 5, 2024

Perception is influenced by sensory stimulation, prior knowledge, and contextual cues, which collectively contribute to the emergence of perceptual biases. However, precise neural mechanisms underlying these biases remain poorly understood. This study aims address this gap analyzing recordings from prefrontal cortex (PFC) monkeys performing a vibrotactile frequency discrimination task. Our findings provide empirical evidence supporting hypothesis that can be reflected in activity PFC. We found state-space trajectories PFC neuronal encoded warped representation first presented during Remarkably, distorted aligned with predictions its Bayesian estimator. The identification correlates expands our understanding basis highlights involvement shaping experiences. Similar analyses could employed other delayed comparison tasks various brain regions explore where how reflects different stages trial.

Язык: Английский

Процитировано

1
Prefrontal Cortex Neural Correlates of the Contraction Bias in Frequency Discrimination DOI Creative Commons

Luis Serrano-Fernández,

Manuel Beirán, Ranulfo Romo

и другие.

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2023, Номер unknown

Опубликована: Июль 28, 2023

Abstract Perception is influenced by sensory stimulation, prior knowledge, and contextual cues, which collectively contribute to the emergence of perceptual biases. However, precise neural mechanisms underlying these biases remain poorly understood. This study aims address this gap analyzing recordings from prefrontal cortex (PFC) monkeys performing a vibrotactile frequency discrimination task. Our findings provide empirical evidence supporting hypothesis that can be reflected in activity PFC. We found state-space trajectories PFC neuronal encoded warped representation first presented during Remarkably, distorted aligned with predictions its Bayesian estimator. The identification correlates expands our understanding basis highlights involvement shaping experiences. Similar analyses could employed other delayed comparison tasks various brain regions explore where how reflects different stages trial.

Язык: Английский

Процитировано

1