Lateral frontoparietal functional connectivity based on individual sulcal morphology DOI Creative Commons
Suvi Häkkinen, Willa I. Voorhies, Ethan H. Willbrand

и другие.

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Апрель 18, 2024

Abstract A salient neuroanatomical feature of the human brain is its pronounced cortical folding, and there mounting evidence that sulcal morphology relevant to functional architecture cognition. However, our understanding relationships between anatomy, activity, behavior still in infancy. We previously found depth three small, shallow sulci lateral prefrontal cortex (LPFC) was linked reasoning performance childhood adolescence (Voorhies et al., 2021). These findings beg question: what linking mechanism cognition? To shed light on this question, we investigated connectivity among LPFC parietal (LPC). leveraged manual parcellations (21 sulci/hemisphere, total 1806) magnetic resonance (fMRI) data from a task 43 participants aged 7–18 years (20 female). conducted clustering classification analyses individual- level sulci. Broadly, 1) patterns individual could be differentiated – more accurately than rotated labels equated for size shape; 2) did not consistently correspond with probabilistic or large-scale networks; 3) clustered together into groups similar patterns, dictated by spatial proximity; 4) across individuals, greater associated higher network centrality several under investigation. results highlight can meaningfully anchored demonstrate vary as function depth. Significance Statement salient, behaviorally relevant, folding. links anatomy are poorly understood particularly shallow, individually variable association cortices. Here, focusing defined regions, offer novel, anatomically informed approach defining connectomes. Further, demonstrate, first time, link morphology.

Язык: Английский

Hubs and interaction: the brain’s meta-loop DOI Creative Commons
Cornelius Weiller, Marco Reisert, Pierre LeVan

и другие.

Cerebral Cortex, Год журнала: 2025, Номер 35(3)

Опубликована: Март 1, 2025

We must reconcile the needs of internal world and demands external to make decisions relevant homeostasis, well-being, flexible behavior. Engagement with (eg interoceptive) is linked medial brain systems, whereas extrapersonal space exteroceptive) associated lateral systems. Using Human Connectome Project data, we found three association tracts connecting action-related frontal lobe perception-related posterior lobes. A dorsal tract a interact independently ventral at hubs. The two hubs are interconnected, forming meta-loop that integrates four anatomical correspond common nodes intrinsic cognitive networks such as default mode network. These functional depend on integration both realms. Thus, positioning can be understood intersection long tracts. strength structural connectivity within systems correlates performance behavioral tests assessing theory mind. provides an framework associate neurological psychiatric symptoms changes.

Язык: Английский

Процитировано

0
Topography of cognition: Evolution of parallel distributed association networks in primates DOI
Randy L. Buckner

Elsevier eBooks, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0
Lateral frontoparietal functional connectivity based on individual sulcal morphology DOI Creative Commons
Suvi Häkkinen, Willa I. Voorhies, Ethan H. Willbrand

и другие.

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Апрель 18, 2024

Abstract A salient neuroanatomical feature of the human brain is its pronounced cortical folding, and there mounting evidence that sulcal morphology relevant to functional architecture cognition. However, our understanding relationships between anatomy, activity, behavior still in infancy. We previously found depth three small, shallow sulci lateral prefrontal cortex (LPFC) was linked reasoning performance childhood adolescence (Voorhies et al., 2021). These findings beg question: what linking mechanism cognition? To shed light on this question, we investigated connectivity among LPFC parietal (LPC). leveraged manual parcellations (21 sulci/hemisphere, total 1806) magnetic resonance (fMRI) data from a task 43 participants aged 7–18 years (20 female). conducted clustering classification analyses individual- level sulci. Broadly, 1) patterns individual could be differentiated – more accurately than rotated labels equated for size shape; 2) did not consistently correspond with probabilistic or large-scale networks; 3) clustered together into groups similar patterns, dictated by spatial proximity; 4) across individuals, greater associated higher network centrality several under investigation. results highlight can meaningfully anchored demonstrate vary as function depth. Significance Statement salient, behaviorally relevant, folding. links anatomy are poorly understood particularly shallow, individually variable association cortices. Here, focusing defined regions, offer novel, anatomically informed approach defining connectomes. Further, demonstrate, first time, link morphology.

Язык: Английский

Процитировано

0