Per- and polyfluoroalkyl substances (PFAS): Trends in mass spectrometric analysis for human biomonitoring and exposure patterns from recent global cohort studies

Environment International, Год журнала: 2024, Номер 194, С. 109117 - 109117

Опубликована: Ноя. 7, 2024

Per- and polyfluoroalkyl substances (PFAS) are widespread environmental contaminants that have been shown to contribute human exposure, thereby raising a range of health concerns. In this context, biomonitoring is essential for linking exposure levels PFAS with their potential risks. Mass spectrometry-based analytical techniques extensively adopted the evaluation across various cohorts. However, challenges arising from use biological samples (e.g., plasma, serum, urine, etc.) necessitate ongoing research refinement methodologies. This review provides an overview current trends in mass approaches PFAS, including sample collection preparation, instrumental techniques. We also explore strategies overcome obtaining PFAS-free blank matrices address risk background contamination. Moreover, examines differing patterns regions by analyzing recent international cohort studies, specifically those conducted US China over past five years. Accordingly, several key gaps studies need be addressed moving forward highlighted.

Язык: Английский

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Deep eutectic solvent-functionalized amorphous UiO-66 for efficient extraction and ultrasensitive analysis of perfluoroalkyl substances in infant milk powder

Food Chemistry X, Год журнала: 2024, Номер 23, С. 101555 - 101555

Опубликована: Июнь 13, 2024

In this study, a convenient and effective method for determination of perfluoroalkyl substances (PFASs) in infant formula was developed based on novel dispersive solid-phase extraction using deep eutectic solvent-functionalized amorphous UiO-66 (DES/aUiO-66) as sorbent. The synthesis materials could be achieved without the use complex environmentally unfriendly procedures. Parameters were systematically investigated to establish simple, fast, efficient green pretreatment method. demonstrated high sensitivity, good precision, detection limit 0.330–0.529 ng·kg−1, low matrix effects (< 12.8%). mechanism material elucidated by ab initio molecular dynamics (AIMD) simulations quantum chemistry calculations. presence massive pore structures collectively synergistic binding sites facilitated affinity adsorption toward PFASs. Finally, applied monitoring PFASs 10 actual milk powder samples. This groundbreaking approach opens new possibilities advancement analytical techniques food safety monitoring.

Язык: Английский

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Climate Actions, Persistent Pollutants, and Human Health: A Call for Integrated Assessments

Environmental Science & Technology, Год журнала: 2024, Номер 58(36), С. 15885 - 15887

Опубликована: Авг. 28, 2024

Язык: Английский

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Associations between in utero exposure of per- and polyfluoroalkyl substances (PFAS) mixture and anthropometry measures at birth

Environmental Pollution, Год журнала: 2025, Номер unknown, С. 126093 - 126093

Опубликована: Март 1, 2025

Язык: Английский

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