Recent Advances in Separation and Analysis of Chiral Compounds

Analytical Chemistry, Год журнала: 2023, Номер 95(1), С. 304 - 318

Опубликована: Янв. 10, 2023

ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTRecent Advances in Separation and Analysis of Chiral CompoundsHai-Long QianHai-Long QianState Key Laboratory Food Science Technology, Jiangnan University, Wuxi 214122, ChinaInternational Joint on Safety, ChinaInstitute Analytical School ChinaMore by Hai-Long QianView Biographyhttps://orcid.org/0000-0001-7554-4115, Shu-Ting XuShu-Ting XuState XuView Biography, Xiu-Ping Yan*Xiu-Ping YanState ChinaKey Synthetic Biological Colloids, Ministry Education, Chemical Material Engineering, China*[email protected]More YanView Biographyhttps://orcid.org/0000-0001-9953-7681Cite this: Anal. Chem. 2023, 95, 1, 304–318Publication Date (Web):January 10, 2023Publication History Received4 October 2022Published online10 January 2023Published inissue 10 2023https://pubs.acs.org/doi/10.1021/acs.analchem.2c04371https://doi.org/10.1021/acs.analchem.2c04371review-articleACS PublicationsCopyright © 2023 American SocietyRequest reuse permissionsArticle Views3966Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum full text article downloads since November 2008 (both PDF HTML) across all institutions individuals. These metrics regularly updated to reflect usage leading up last few days.Citations number other articles citing this article, calculated Crossref daily. Find more information about citation counts.The Altmetric Attention Score is a quantitative measure attention that research has received online. Clicking donut icon will load page at altmetric.com with additional details score social media presence for given article. how calculated. Share Add toView InAdd Full Text ReferenceAdd Description ExportRISCitationCitation abstractCitation referencesMore Options onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Chromatography,Covalent organic frameworks,High-performance liquid chromatography,Membranes,Molecular structure Get e-Alerts

Язык: Английский

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A Look at the Importance of Chirality in Drug Activity: Some Significative Examples

Applied Sciences, Год журнала: 2022, Номер 12(21), С. 10909 - 10909

Опубликована: Окт. 27, 2022

Chirality plays an important role in the development of many pharmaceuticals, being a general property ‘handedness’; nevertheless, large number pharmaceuticals are still marketed and administered as racemates. is all around even within us; indeed, receptors enzymes chiral entities interact specific manner with drugs. Consequently, controlling enantiomeric purity isolating enantiomers from drugs remains crucial subject for analytical, clinical, regulatory purposes, thus, improving drug safety profile. The classical examples spontaneous enantiomerization severe toxicity related to chirality represented by ibuprofen thalidomide, respectively, but numerous other cases have been reported literature. This review intends offer brief overview on most common used therapy treatment various diseases.

Язык: Английский

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Chiral Materials: Progress, Applications, and Prospects

Small, Год журнала: 2023, Номер 19(38)

Опубликована: Май 22, 2023

Abstract Chirality is a universal phenomenon in molecular and biological systems, denoting an asymmetric configurational property where object cannot be superimposed onto its mirror image by any kind of translation or rotation, which ubiquitous on the scale from neutrinos to spiral galaxies. plays very important role life system. Many molecules body show chirality, such as “codebook” earth's diversity‐DNA, nucleic acid, etc. Intriguingly, living organisms hierarchically consist homochiral building blocks, for example, l ‐amino acids d ‐sugars with unknown reason. When chirality interact these chiral factors, only one conformation favors positive development life, that is, host environment can selectively conformations. The differences interactions are often manifested recognition, mutual matching, molecules, means stereoselectivity produce changes pharmacodynamics pathology. Here, latest investigations summarized including construction applications materials based natural small source, biomacromolecules sources, material synthesized design source.

Язык: Английский

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Recent progress of membrane technology for chiral separation: A comprehensive review

Separation and Purification Technology, Год журнала: 2023, Номер 309, С. 123077 - 123077

Опубликована: Янв. 2, 2023

Язык: Английский

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Advances in membrane-based chiral separation

Coordination Chemistry Reviews, Год журнала: 2023, Номер 495, С. 215392 - 215392

Опубликована: Авг. 21, 2023

Язык: Английский

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Molecularly Imprinted Nanomaterials with Stimuli Responsiveness for Applications in Biomedicine

Molecules, Год журнала: 2023, Номер 28(3), С. 918 - 918

Опубликована: Янв. 17, 2023

The review aims to summarize recent reports of stimuli-responsive nanomaterials based on molecularly imprinted polymers (MIPs) and discuss their applications in biomedicine. In the past few decades, MIPs have been proven show widespread as new molecular recognition materials. development has successfully endowed with not only affinity properties comparable those natural antibodies but also ability respond external stimuli (stimuli-responsive MIPs). this review, we will synthesis MIPs, classification MIP (MIP-NMs), dynamic mechanisms, biomedicine, including bioanalysis diagnosis, biological imaging, drug delivery, disease intervention, others. This mainly focuses studies smart MIP-NMs biomedical perspectives after 2015. We believe that be helpful for further exploration contribute expanding practical especially biomedicine near future.

Язык: Английский

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Chiral Ni-Al LDH nanoparticle embedded electrospun nanofibrous membrane with high and stable permeance for enantioseparation of ketoprofen

Separation and Purification Technology, Год журнала: 2025, Номер unknown, С. 131443 - 131443

Опубликована: Янв. 1, 2025

Язык: Английский

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Surface molecular imprinted membranes as a “gate” for selective transdermal release of chiral drug amlodipine

Journal of Membrane Science, Год журнала: 2022, Номер 664, С. 121059 - 121059

Опубликована: Окт. 5, 2022

Язык: Английский

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Chiral separation by capillary electrokinetic chromatography with hydrophobic deep eutectic solvents as pseudo-stationary phases

Talanta, Год журнала: 2023, Номер 260, С. 124556 - 124556

Опубликована: Апрель 18, 2023

Язык: Английский

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Preparation and application of a chiral Am7CD-modified COF composite membrane by interfacial polymerization

Separation and Purification Technology, Год журнала: 2023, Номер 323, С. 124406 - 124406

Опубликована: Июнь 22, 2023

Язык: Английский

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