Advances in green sample preparation methods for bioanalytical laboratories focusing on drug analysis

Bioanalysis, Год журнала: 2025, Номер unknown, С. 1 - 20

Опубликована: Март 24, 2025

Bioanalytical laboratories face significant challenges in sample preparation due to the complexity of biological matrices and low concentrations target analytes. This review focuses on advances green (GSP) techniques tailored meet these while promoting sustainability. Innovations sorbents, including metal-organic frameworks (MOFs), magnetic nanoparticles (MNPs), sol-gel-based materials, molecularly imprinted polymers (MIPs), carbon-based natural sorbents like cellulose kapok fiber, have enhanced extraction efficiency selectivity. Green solvents such as deep eutectic (DES), ionic liquids (ILs), supramolecular (SUPRAs), switchable hydrophilicity (SHSs) further reduce environmental impact by minimizing toxic solvent use. highlights their use drug analysis, emphasizing roles enhancing efficiency, selectivity, Recent applications demonstrate integration into bioanalytical workflows, significantly improving analytical performance adhering Analytical Chemistry (GAC) principles. It is anticipated that this comprehensive will aid scholars formulation selective, rapid, environmentally friendly, straightforward, sensitive, precise methodologies for bioanalysis, thereby innovation sustainability within analysis protocols.

Язык: Английский

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Carbon fiber felt as a novel sorbent for the easy detection of environmental pollutants: Application to the analysis of polycyclic aromatic hydrocarbons

Journal of Food Composition and Analysis, Год журнала: 2025, Номер unknown, С. 107416 - 107416

Опубликована: Фев. 1, 2025

Язык: Английский

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Sorbent-Based Microextraction Combined with GC-MS: A Valuable Tool in Bioanalysis

Chemosensors, Год журнала: 2025, Номер 13(2), С. 71 - 71

Опубликована: Фев. 16, 2025

Sample preparation is broadly recognized as the most critical, time-consuming, and error-prone step of a bioanalytical workflow. Over years, development pretreatment methods aimed at isolation preconcentration target analytes from sample matrices has been an ongoing effort. Recent innovations have miniaturizing to streamline laboratory processes enhance analytical performance. Sorbent-based microextraction techniques, including solid-phase microextraction, by packed sorbent, bar adsorptive capsule phase etc., recently gained attention effective tools prior gas chromatography-mass spectrometric analysis. This article provides overview GC-MS applications sorbent-based techniques published in last decade (2014–2024) that enable efficient sensitive determination various compounds biological samples.

Язык: Английский

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Forensic analysis towards green analytical chemistry: Developments and perspectives in sample preparation

Comprehensive analytical chemistry, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Язык: Английский

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Determination of tramadol and its main metabolite in pericardial fluid by dispersive liquid–liquid microextraction combined with gas chromatography–mass spectrometry

Microchemical Journal, Год журнала: 2025, Номер unknown, С. 114138 - 114138

Опубликована: Май 1, 2025

Язык: Английский

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Nanosensing for tramadol detection: Innovative opioid analysis

Clinica Chimica Acta, Год журнала: 2025, Номер 576, С. 120414 - 120414

Опубликована: Июнь 2, 2025

Язык: Английский

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