Advanced Functional Materials,
Год журнала:
2023,
Номер
34(6)
Опубликована: Окт. 22, 2023
Abstract
Encapsulation
is
a
promising
technology
to
enhance
the
pharmacokinetic
properties
of
proteins
and
peptides,
particularly
addressing
their
short
half‐life.
Despite
its
potential,
this
method
has
limitations,
such
as
low
encapsulation
efficiency,
minimal
mass
fraction
therapeutic
agents,
potential
loss
biological
activity.
In
study,
pivotal
role
amphiphilic
polymers
in
achieving
efficient
protein
peptide
delved
into.
It
found
that
these
not
only
improve
solvation
cargo
nanoparticles
but
also
form
robust
3D
polymer
layer
at
oil/water
interface.
This
interfacial
barrier
effectively
minimizes
escape
peptides
during
process,
an
impressive
efficiency
up
99.8%
for
agents.
Remarkably,
agents
resultant
microparticles
exceed
59.9
wt.%.
The
prolonged
payload
release
30
days
both
vitro
vivo,
leading
heightened
efficacy
type
2
diabetic
rats.
Furthermore,
required
amount
administration
reduced
by
factor
47.5,
substantially
mitigating
inflammatory
response
injection
site.
conclusion,
findings
highlight
transformative
using
accumulation
encapsulate
peptides.
Scientific Reports,
Год журнала:
2023,
Номер
13(1)
Опубликована: Окт. 10, 2023
Abstract
Corrosion
constitutes
a
significant
issue
in
industries
that
handle
metals.
inhibitors
with
low
impact
on
the
environment
provide
economic
benefit
various
engineering
applications.
In
this
work,
effectiveness
of
olive
leaves
extract
is
evaluated
as
cost-effective
and
environmentally-friendly
corrosion
inhibitor.
The
carbon
steel
different
concentrations
hydrochloric
acid
(0.1,
1.0,
2.0
M)
when
protected
by
an
aqueous
solution
leaf
ranging
from
10
to
60
ppm
investigated.
A
green
extraction
process
based
upon
water
used
ensure
minimum
environment.
Results
show
inhibition
efficiency
increased
concentration
increased.
An
analysis
variance
showed
effect
acidic
molarity,
temperature,
inhibitor
rate.
statistical
model
indicates
exhibits
higher
efficiencies
at
molarity.
SEM
EDX
also
demonstrated
protective
film
specimen
surface
plays
role
inhibition,
suggesting
molecules
are
adsorbed
interface
between
solution.
study
provides
insight
mechanism
highlights
potential
oil
eco-friendly
alternative
traditional
inhibitors.
Journal of Surfactants and Detergents,
Год журнала:
2024,
Номер
27(4), С. 483 - 496
Опубликована: Янв. 28, 2024
Abstract
In
the
current
study,
a
tetracationic
quaternary
ammonium
salt
(TCQAC)
was
synthesized
and
characterized
its
ability
to
suppress
corrosion
on
mild
steel
(MS)
in
0.5
M
H
2
SO
4
solution
examined.
Various
chemical,
electrochemical,
surface
characterization
techniques
were
utilized
study
inhibition
efficiency
of
TCQAC.
The
TCQAC
manifests
99.83%
at
20
ppm
concentration.
Out
all
examined
isotherm
models,
Langmuir
offered
best
fit
for
adsorption
MS
surface.
A
very
high
negative
value
Δ
G
ads
(−45.18
kJ
mol
−1
)
suggests
that
followed
chemisorption
mechanism.
Electrochemical
studies
indicate
increases
linear
charge
transfer
resistances
(LPR
R
ct
,
respectively).
slows
down
anodic
cathodic
Tafel
reactions;
however,
it
acts
as
an
anodic‐type
inhibitor
5,
10,
ppm.
appearance
extra
Cl
N
signals
energy
dispersive
x‐ray
(EDX)
spectrum
improvement
smoothness
scanning
electron
microscope
(SEM)
image
inhibited
sample
corroborated
method
inhibition.
X‐ray
photoelectron
spectroscopy
(XPS)
indicates
creates
preventive
layers
by
chemical
adsorption.
Frontier
molecular
orbitals
(FMOs),
highest
occupied
orbital
(HOMO)
lowest
unoccupied
(LUMO)
delocalized
around
central
part
comprises
two
benzyls,
four
allyls,
one
hydrocarbon
((CH
)
6
)
moieties
nitrogen
atoms.
outcomes
XPS
density
functional
theory
(DFT)
analyses
occurs
dπ–pπ
bonding
with
iron
π‐electrons
aryl
allyl
extensively
participate
bonding.
Tenside Surfactants Detergents,
Год журнала:
2024,
Номер
61(6), С. 599 - 610
Опубликована: Сен. 11, 2024
Abstract
In
view
of
the
simultaneous
demand
for
surfactants
and
corrosion
inhibitors
in
oilfield
production,
new
with
both
low
interfacial
tension
inhibition
function
were
successfully
prepared
this
work
by
amidation
carboxymethylation
using
fatty
acids
amines
as
raw
materials.
The
surfactant
was
investigated
a
rotational
tensiometer,
critical
micelle
concentration
determined.
properties
dual-functional
agents
measured
weight
loss
experiments,
electrochemical
tests,
scanning
electron
microscopy
(SEM).
results
showed
that
exhibited
10
−2
mN
m
−1
.
possessed
promising
effects.
Electrochemical
tests
SEM
analysis
an
adsorption
layer
preventing
formed
on
surface
A3
steel.
followed
Langmuir
isotherm.
experimental
data
also
supported
quantum
calculations.
Advanced Functional Materials,
Год журнала:
2023,
Номер
34(6)
Опубликована: Окт. 22, 2023
Abstract
Encapsulation
is
a
promising
technology
to
enhance
the
pharmacokinetic
properties
of
proteins
and
peptides,
particularly
addressing
their
short
half‐life.
Despite
its
potential,
this
method
has
limitations,
such
as
low
encapsulation
efficiency,
minimal
mass
fraction
therapeutic
agents,
potential
loss
biological
activity.
In
study,
pivotal
role
amphiphilic
polymers
in
achieving
efficient
protein
peptide
delved
into.
It
found
that
these
not
only
improve
solvation
cargo
nanoparticles
but
also
form
robust
3D
polymer
layer
at
oil/water
interface.
This
interfacial
barrier
effectively
minimizes
escape
peptides
during
process,
an
impressive
efficiency
up
99.8%
for
agents.
Remarkably,
agents
resultant
microparticles
exceed
59.9
wt.%.
The
prolonged
payload
release
30
days
both
vitro
vivo,
leading
heightened
efficacy
type
2
diabetic
rats.
Furthermore,
required
amount
administration
reduced
by
factor
47.5,
substantially
mitigating
inflammatory
response
injection
site.
conclusion,
findings
highlight
transformative
using
accumulation
encapsulate
peptides.
