Two-dimensional nanomaterials-based optical biosensors empowered by machine learning for intelligent diagnosis

TrAC Trends in Analytical Chemistry, Год журнала: 2025, Номер unknown, С. 118162 - 118162

Опубликована: Фев. 1, 2025

Язык: Английский

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The potentials of advanced materials for the chemo- and bio-sensing of gluten and its derivatives in food samples

Trends in Food Science & Technology, Год журнала: 2025, Номер unknown, С. 104958 - 104958

Опубликована: Март 1, 2025

Язык: Английский

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Aptamer Paper-Based Fluorescent Sensor for Determination of SARS-CoV-2 Spike Protein

Sensors, Год журнала: 2025, Номер 25(6), С. 1637 - 1637

Опубликована: Март 7, 2025

Point-of-care (POC) antigen detection plays a crucial role in curbing the spread of viruses. Paper-based fluorescence aptasensors are expected to offer low-cost tool meet needs decentralized POC diagnosis. Herein, we report on fluorescent paper-based sensing system for detecting SARS-CoV-2 spike protein. The was constructed by loading multi-layer Nb2C MXene nano-quenchers and carbon-dot-labeled aptamer (G-CDs@Apt) probes onto mixed cellulose ester (MCE) paper substrate. On MXene/G-CDs@Apt paper, abundant G-CDs@Apt were attached multilayer kept fluorescence-off state, while recognition target detached formed nano--quenchers, resulting recovery paper. developed sensor performed well one-step S1 protein with limit 0.067 ng/mL (0.335 pg/test). assay exhibited good selectivity anti-interference artificial saliva. Moreover, aptasensor successfully used detect actual environmental samples recoveries 90.87–100.55% relative standard deviations 1.52–3.41%. proposed technology provides cost-effective alternative traditional antibody test strips wide range diagnostic applications.

Язык: Английский

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Exploring Green Practices: a Review of Carbon Dot-Based Sustainable Sensing Approaches

Journal of Fluorescence, Год журнала: 2025, Номер unknown

Опубликована: Март 17, 2025

Язык: Английский

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