The global burden of metabolic disease: Data from 2000 to 2019

Cell Metabolism, Год журнала: 2023, Номер 35(3), С. 414 - 428.e3

Опубликована: Март 1, 2023

Язык: Английский

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Global epidemiology of cirrhosis — aetiology, trends and predictions

Nature Reviews Gastroenterology & Hepatology, Год журнала: 2023, Номер 20(6), С. 388 - 398

Опубликована: Март 28, 2023

Язык: Английский

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Global trends in hepatocellular carcinoma epidemiology: implications for screening, prevention and therapy

Nature Reviews Clinical Oncology, Год журнала: 2023, Номер 20(12), С. 864 - 884

Опубликована: Окт. 26, 2023

Язык: Английский

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Global incidence and prevalence of nonalcoholic fatty liver disease

Clinical and Molecular Hepatology, Год журнала: 2022, Номер 29(Suppl), С. S32 - S42

Опубликована: Дек. 15, 2022

Nonalcoholic fatty liver disease (NAFLD) is a leading cause of worldwide. The estimated global incidence NAFLD 47 cases per 1,000 population and higher among males than females. prevalence adults 32% (40%) compared to females (26%). has increased over time, from 26% in studies 2005 or earlier 38% 2016 beyond. varies substantially by world region, contributed differing rates obesity, genetic socioeconomic factors. exceeds 40% the Americas South-East Asia. projected increase significantly multiple regions 2030 if current trends are left unchecked. In this review, we discuss future projections.

Язык: Английский

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Changing epidemiology, global trends and implications for outcomes of NAFLD

Journal of Hepatology, Год журнала: 2023, Номер 79(3), С. 842 - 852

Опубликована: Май 10, 2023

Non-alcoholic fatty liver disease (NAFLD) has rapidly become the most common globally, currently estimated to affect 38% of global population. A minority patients with NAFLD will progress cirrhosis or hepatocellular carcinoma, but total number this vast population that risk such severe outcomes is increasing. Worryingly, persons are affected by at an earlier age, suggesting they have longer time develop complications. With considerable changes in diet composition and urbanization, obesity type 2 diabetes among population, particular developing countries, proportion projected be further Yet, there large geographical discrepancies prevalence rates its inflammatory component non-alcoholic steatohepatitis (NASH). Such differences partly related differing socio-economic milieus, also genetic predisposition.This narrative review discusses recent epidemiology NASH from regional perspectives, as well special populations. We discuss consequences these can on hepatic extra-hepatic events.

Язык: Английский

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Global epidemiology of alcohol-associated cirrhosis and HCC: trends, projections and risk factors

Nature Reviews Gastroenterology & Hepatology, Год журнала: 2022, Номер 20(1), С. 37 - 49

Опубликована: Окт. 18, 2022

Heavy alcohol consumption is a major cause of morbidity and mortality. Globally, per-capita rose from 5.5 litres in 2005 to 6.4 2016 projected increase further 7.6 2030. In 2019, an estimated 25% global cirrhosis deaths were associated with alcohol. The age-standardized death rate (ASDR) alcohol-associated was 4.5 per 100,000 population, the highest lowest ASDR Africa Western Pacific, respectively. annual incidence hepatocellular carcinoma (HCC) among patients ranged 0.9% 5.6%. Alcohol approximately one-fifth HCC-related 2019. Between 2012 2017, for declined, but liver cancer increased. Measures are required curb heavy reduce burden HCC. Degree intake, sex, older age, obesity, type 2 diabetes mellitus, gut microbial dysbiosis genetic variants key factors development this Review, we discuss epidemiology, projections risk

Язык: Английский

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Global burden of hepatitis B virus: current status, missed opportunities and a call for action

Nature Reviews Gastroenterology & Hepatology, Год журнала: 2023, Номер 20(8), С. 524 - 537

Опубликована: Апрель 6, 2023

Язык: Английский

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Current status and future trends of the global burden of MASLD

Trends in Endocrinology and Metabolism, Год журнала: 2024, Номер 35(8), С. 697 - 707

Опубликована: Фев. 29, 2024

Язык: Английский

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A prospective study on the prevalence of NAFLD, advanced fibrosis, cirrhosis and hepatocellular carcinoma in people with type 2 diabetes

Journal of Hepatology, Год журнала: 2022, Номер 78(3), С. 471 - 478

Опубликована: Ноя. 19, 2022

Язык: Английский

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The role of hepatokines in NAFLD

Cell Metabolism, Год журнала: 2023, Номер 35(2), С. 236 - 252

Опубликована: Фев. 1, 2023

Язык: Английский

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