Sequential in situ self-assembly/dis-assembly of methylated quinoline silicon(Ⅳ) phthalocyanines: a lysosome two-photon probe and type I/II photodynamic synergistic photothermal therapeutic sensitizer

Sensors and Actuators B Chemical, Год журнала: 2025, Номер unknown, С. 137517 - 137517

Опубликована: Фев. 1, 2025

Язык: Английский

---

Detecting Changes in Singlet Oxygen and Viscosity during Apoptosis-Ferroptosis Mediated Photodynamic Therapy and Establishing Visual Imaging of Fatty Liver

ACS Sensors, Год журнала: 2025, Номер unknown

Опубликована: Март 11, 2025

Cancer is a serious global health threat, and photodynamic therapy (PDT) an effective treatment method for cancer. This works by generating large amount of singlet oxygen (1O2) under the influence light, which induces apoptosis in tumor cells, leading to their destruction. However, resistance cells limits development PDT, thus combination ferroptosis provides new perspective PDT. During PDT ferroptosis, levels 1O2 microenvironment (viscosity) within often change. To address this, this study developed novel fluorescent probe, NI–QM-OH, based on TICT–ICT effect, capable monitoring changes viscosity during The probe exhibits excellent selectivity, high sensitivity, low LOD (0.38 μM), has been successfully applied bioimaging HepG2, HeLa, MCF-7 as well zebrafish. Most importantly, NI–QM–OH also enables visualization diagnosis fatty liver disease (both alcoholic nonalcoholic).

Язык: Английский

---

Mitochondrial Activation via Calcium Peroxide/Carrageenan/Soybean Lecithin-Derived Polypyrrole Phototherapeutic Microparticles

Colloids and Surfaces B Biointerfaces, Год журнала: 2025, Номер unknown, С. 114787 - 114787

Опубликована: Май 1, 2025

Язык: Английский

---

Injectable Nanosuspension based on Orthoester for Synergistic Chemo-Photothermal/Gas Therapy in Localized Cancer Treatment

Colloids and Surfaces B Biointerfaces, Год журнала: 2025, Номер 254, С. 114841 - 114841

Опубликована: Июнь 1, 2025

Язык: Английский

---