Study on the inhibition of non-small cell lung cancer mediated by chitosan-based gene carrier delivering STAT3-shRNA DOI Creative Commons
Wangwang Zhang, Liqiang Song,

Yi Zhou

и другие.

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 284, С. 138211 - 138211

Опубликована: Ноя. 29, 2024

Язык: Английский

Advancing Cancer Therapy with Quantum Dots and Other Nanostructures: A Review of Drug Delivery Innovations, Applications, and Challenges DOI Open Access
Ashutosh Pareek,

Deepanjali Kumar,

Aaushi Pareek

и другие.

Cancers, Год журнала: 2025, Номер 17(5), С. 878 - 878

Опубликована: Март 4, 2025

Nanotechnology, particularly quantum dots (QDs), has ushered in a transformative era the pharmaceutical and medical industries, offering notable opportunities for nanoscale advancements. These particles, known their exceptional optical properties confinement, have emerged as indispensable tools cancer drug delivery bioimaging. This review delves into various conjugation techniques with QDs, including covalent linking, non-covalent conjugation, click chemistry, disulfide linkage, pH-sensitive linkage. Each method provides distinct advantages, such enhanced stability, reversibility, specificity, controlled release. Moreover, QDs demonstrated significant promise oncology by efficiently delivering drugs to cancerous tissues while minimising systemic toxicity. Investigations applications different cancers, blood, brain, cervical, breast etc., reveal efficacy targeted delivery, real-time imaging, improved therapeutic outcomes. However, challenges potential toxicity, pharmacokinetics, targeting specificity must be addressed fully harness benefits of therapy. Future research should focus on developing biocompatible optimising techniques, elucidating safety profiles long-term effects biological systems. Overall, represent promising frontier treatment, multifaceted capabilities that hold outcomes reduced side across cancers.

Язык: Английский

Процитировано

6
Tannic acid cross-linked polyethylenimine quantum dot nanoclusters for efficient DNA release DOI
Mingjie Wang,

Yuqiu Zheng,

Guowei Qi

и другие.

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 143055 - 143055

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0
Synthesis of low molecular weight polyethylene imine-polyamidoamine hybrid and its modified derivatives as efficient nanocarriers for pDNA and CRISPR/Cas9 delivery DOI
Mohammad Sadegh Amiri, Akbar Shojaei, Shohreh Mashayekhan

и другие.

International Journal of Pharmaceutics, Год журнала: 2025, Номер 680, С. 125778 - 125778

Опубликована: Май 26, 2025

Язык: Английский

Процитировано

0
Integrated cell membrane encapsulated PQDs-TK quantum dot nanoclusters with ROS-responsive triggering for efficient and visualized DNA delivery DOI
Tiange Wang,

Yanlin Sun,

Dong Zeng

и другие.

Journal of Colloid and Interface Science, Год журнала: 2024, Номер 683, С. 393 - 410

Опубликована: Дек. 25, 2024

Язык: Английский

Процитировано

1
Study on the inhibition of non-small cell lung cancer mediated by chitosan-based gene carrier delivering STAT3-shRNA DOI Creative Commons
Wangwang Zhang, Liqiang Song,

Yi Zhou

и другие.

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 284, С. 138211 - 138211

Опубликована: Ноя. 29, 2024

Язык: Английский

Процитировано

0