medRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 10, 2024
Abstract
Deep
learning
models
have
shown
substantial
promise
in
assisting
medical
diagnosis,
offering
the
potential
to
improve
patient
outcomes
and
reduce
clinician
workloads.
However,
widespread
adoption
of
these
clinical
practice
has
been
hindered
by
concerns
surrounding
their
trustworthiness,
transparency,
interpretability.
Addressing
challenges
requires
not
only
development
explainable
AI
(xAI)
techniques
but
also
quantitative
metrics
evaluate
effectiveness.
This
study
presents
a
comprehensive
framework
for
training,
explaining,
quantitatively
assessing
deep
skin
cancer
diagnosis.
Leveraging
HAM10000
dataset
seven
diagnostic
lesion
categories,
multiple
convolutional
neural
network
architectures—including
custom
CNNs,
DenseNet,
MobileNet,
ResNet—were
trained
optimized
using
augmentation,
oversampling,
hyperparameter
tuning.
Following
model
explainability
such
as
SHAP,
LIME,
Integrated
Gradients
were
deployed
generate
post
hoc
explanations.
Critically,
primary
contribution
this
work
is
evaluation
explanation
methods
related
faithfulness,
robustness,
complexity.
All
code,
models,
results
are
publicly
available,
providing
reproducible
pathway
toward
more
trustworthy,
tools.
Machine Learning and Knowledge Extraction,
Год журнала:
2024,
Номер
6(1), С. 699 - 736
Опубликована: Март 21, 2024
In
this
review,
we
compiled
convolutional
neural
network
(CNN)
methods
which
have
the
potential
to
automate
manual,
costly
and
error-prone
processing
of
medical
images.
We
attempted
provide
a
thorough
survey
improved
architectures,
popular
frameworks,
activation
functions,
ensemble
techniques,
hyperparameter
optimizations,
performance
metrics,
relevant
datasets
data
preprocessing
strategies
that
can
be
used
design
robust
CNN
models.
also
machine
learning
algorithms
for
statistical
modeling
current
literature
uncover
latent
topics,
method
gaps,
prevalent
themes
future
advancements.
The
results
indicate
temporal
shift
in
favor
designs,
such
as
from
use
architecture
CNN-transformer
hybrid.
insights
point
surge
practitioners
into
imaging
field,
partly
driven
by
COVID-19
challenge,
catalyzed
detecting
diagnosing
pathological
conditions.
This
phenomenon
likely
contributed
sharp
increase
number
publications
on
CNNs
imaging,
both
during
after
pandemic.
Overall,
existing
has
certain
gaps
scope
with
respect
optimization
architectures
specifically
imaging.
Additionally,
there
is
lack
post
hoc
explainability
models
slow
progress
adopting
low-resource
review
ends
list
open
research
questions
been
identified
through
recommendations
potentially
help
set
up
more
robust,
reproducible
experiments
Scientific Reports,
Год журнала:
2025,
Номер
15(1)
Опубликована: Янв. 7, 2025
In
the
present
scenario,
cancerous
tumours
are
common
in
humans
due
to
major
changes
nearby
environments.
Skin
cancer
is
a
considerable
disease
detected
among
people.
This
uncontrolled
evolution
of
atypical
skin
cells.
It
occurs
when
DNA
injury
cells,
or
genetic
defect,
leads
an
increase
quickly
and
establishes
malignant
tumors.
However,
rare
instances,
many
types
occur
from
tempted
by
infrared
light
affecting
worldwide
health
problem,
so
accurate
appropriate
diagnosis
needed
for
efficient
treatment.
Current
developments
medical
technology,
like
smart
recognition
analysis
utilizing
machine
learning
(ML)
deep
(DL)
techniques,
have
transformed
treatment
these
conditions.
These
approaches
will
be
highly
effective
biomedical
imaging.
study
develops
Multi-scale
Feature
Fusion
Deep
Convolutional
Neural
Networks
on
Cancerous
Tumor
Detection
Classification
(MFFDCNN-CTDC)
model.
The
main
aim
MFFDCNN-CTDC
model
detect
classify
using
To
eliminate
unwanted
noise,
method
initially
utilizes
sobel
filter
(SF)
image
preprocessing
stage.
For
segmentation
process,
Unet3+
employed,
providing
precise
localization
tumour
regions.
Next,
incorporates
multi-scale
feature
fusion
combining
ResNet50
EfficientNet
architectures,
capitalizing
their
complementary
strengths
extraction
varying
depths
scales
input
images.
convolutional
autoencoder
(CAE)
utilized
classification
method.
Finally,
parameter
tuning
process
performed
through
hybrid
fireworks
whale
optimization
algorithm
(FWWOA)
enhance
performance
CAE
A
wide
range
experiments
authorize
approach.
experimental
validation
approach
exhibited
superior
accuracy
value
98.78%
99.02%
over
existing
techniques
under
ISIC
2017
HAM10000
datasets.
Medical Physics,
Год журнала:
2024,
Номер
51(8), С. 5270 - 5282
Опубликована: Май 31, 2024
Abstract
Background
Chronic
cerebral
hypoperfusion
(CCH)
is
a
frequently
encountered
clinical
condition
that
poses
diagnostic
challenge
due
to
its
nonspecific
symptoms.
Purpose
To
enhance
the
diagnosis
of
CCH
and
non‐CCH
through
Magnetic
Resonance
Imaging
(MRI),
offering
support
in
decision‐making
recommendations
ultimately
elevate
accuracy
optimize
patient
treatment
outcomes.
Methods
In
retrospective
research,
we
collected
204
routine
brain
magnetic
resonance
imaging
(MRI)
from
March
1
September
10
2022,
as
training
testing
cohorts.
And
validation
cohort
with
108
samples
was
November
14
2022
August
4
2023.
MRI
sequences
were
processed
obtain
T1‐weighted
(T1WI)
T2‐weighted
(T2WI)
sequence
images
for
each
patient.
We
propose
CCH‐Network
(CCHNet),
an
end‐to‐end
deep
learning
model,
integrating
convolution
Transformer
modules
capture
local
global
structural
information.
Our
novel
adversarial
method
improves
feature
knowledge
capture,
enhancing
both
generalization
ability
efficiency
predicting
risk.
assessed
classification
performance
proposed
model
CCHNet
by
comparing
it
existing
state‐of‐the‐art
algorithms,
including
ResNet34,
DenseNet121,
VGG16,
Convnext,
ViT,
Coat,
TransFG.
better
validate
performance,
compared
results
eight
neurologists
evaluate
their
consistency.
Results
achieved
AUC
91.6%
(95%
CI:
86.8–99.1),
(ACC)
85.0%
75.6–95.2).
It
demonstrated
sensitivity
(SE)
80.0%
71.6–95.6)
specificity
(SP)
90.0%
82.3–97.8)
cohort.
cohort,
86.0%
80.3–93.0),
ACC
84.2%
70.2–93.6),
SE
83.3%
68.3–95.5),
SP
84.7%
70.3–96.8).
Conclusions
The
improved
high
SP,
providing
promising
CCH.
ACM Transactions on Computing for Healthcare,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 4, 2025
This
paper
offers
an
extensive
survey
of
one
the
fundamental
aspects
trustworthiness
Artificial
Intelligence
(AI)
in
healthcare,
namely
uncertainty,
focusing
on
large
panoply
recent
studies
addressing
connection
between
AI,
and
healthcare.
The
concept
uncertainty
is
a
recurring
theme
across
multiple
disciplines,
with
varying
focuses
approaches.
Here,
we
focus
diverse
nature
medical
applications,
emphasizing
importance
quantifying
model
predictions
its
advantages
specific
clinical
settings.
Questions
that
emerge
this
context
range
from
guidelines
for
AI
integration
healthcare
domain
to
ethical
deliberations
their
compatibility
cutting-edge
research.
Together
description
main
works
context,
also
discuss
that,
as
medicine
evolves
introduces
novel
sources
there
need
more
versatile
quantification
methods
be
developed
collaboratively
by
researchers
professionals.
Finally,
acknowledge
limitations
current
different
facets
within
domain.
In
particular,
identify
relative
paucity
approaches
user’s
perception
accordingly
trustworthiness.