Fabrication of hierarchically porous trabecular bone replicas via 3D printing with high internal phase emulsions (HIPEs)

Biofabrication, Год журнала: 2024, Номер 17(1), С. 015012 - 015012

Опубликована: Окт. 25, 2024

Abstract Combining emulsion templating with additive manufacturing enables the production of inherently porous scaffolds multiscale porosity. This approach incorporates interconnected materials, providing a structure that supports cell ingrowth. However, 3D printing hierarchical structures combine semi-micropores and micropores remains challenging task. Previous studies have demonstrated using carefully adjusted combination light absorbers photoinitiators in resin can produce open surface porosity, sponge-like internal structures, resolution about 150 µ m. In this study, we explored how varying concentrations tartrazine (0, 0.02, 0.04, 0.08 wt%) as absorber affect acrylate-based polymerized medium phase emulsions fabricated via vat photopolymerization. Given importance for tissue engineering regenerative medicine, tested behavior on these 3D-printed disk samples MG-63 cells, examining metabolic activity, adhesion, morphology. The wt% tartrazine-containing sample (008 T) best proliferation adhesion. To show high (HIPE) be used to create complex biomedical applications, trabecular bone based microCT imaging. These were further evaluated migration, followed by analysis after 60 days culture. research demonstrates HIPEs print mimics manufacturing, which could developed lab-on-a-chip models healthy diseased bone.

Язык: Английский

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Optimizing mass transfer performance in triply periodic minimal surface porous scaffolds through isosurface offset

Thin-Walled Structures, Год журнала: 2024, Номер unknown, С. 112800 - 112800

Опубликована: Дек. 1, 2024

Язык: Английский

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Polydopamine-assisted loading of bioactive ions onto the multi-scale composite-structured surface of 3D-printed porous Ti-6Al-4V implant to enhance its osteogenic and antibacterial properties

Surfaces and Interfaces, Год журнала: 2025, Номер unknown, С. 106624 - 106624

Опубликована: Май 1, 2025

Язык: Английский

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High-fidelity computational fluid dynamics modeling to simulate perfusion through a bone-mimicking scaffold

Computers in Biology and Medicine, Год журнала: 2024, Номер 186, С. 109637 - 109637

Опубликована: Дек. 31, 2024

Язык: Английский

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