A-to-I-edited miR-1251-5p restrains tumor growth and metastasis in lung adenocarcinoma through regulating TCF7-mediated Wnt signaling pathway DOI Creative Commons

Shuhua Xu,

Zhou Guoping,

Qiyu He

и другие.

Discover Oncology, Год журнала: 2024, Номер 15(1)

Опубликована: Окт. 24, 2024

RNA editing from A (adenine nucleotide) to I (hypoxanthine mediated by ADARs has attracted more and attention as an important post-transcriptional processing method. This research investigates the regulatory mechanism of A-to-I-edited miR-1251-5p in lung adenocarcinoma (LUAD).

Язык: Английский

Artificial intelligence in lung cancer: current applications, future perspectives, and challenges DOI Creative Commons
Dongdong Huang,

Zifang Li,

Tao Jiang

и другие.

Frontiers in Oncology, Год журнала: 2024, Номер 14

Опубликована: Дек. 23, 2024

Artificial intelligence (AI) has significantly impacted various fields, including oncology. This comprehensive review examines the current applications and future prospects of AI in lung cancer research treatment. We critically analyze latest technologies their across multiple domains, genomics, transcriptomics, proteomics, metabolomics, immunomics, microbiomics, radiomics, pathomics research. The elucidates AI’s transformative role enhancing early detection, personalizing treatment strategies, accelerating therapeutic innovations. explore impact on precision medicine cancer, encompassing diagnosis, planning, monitoring, drug discovery. potential analyzing complex datasets, genetic profiles, imaging data, clinical records, is discussed, highlighting its capacity to provide more accurate diagnoses tailored plans. Additionally, we examine predicting patient responses immunotherapy forecasting survival rates, particularly non-small cell (NSCLC). addresses technical challenges facing implementation care, data quality quantity issues, model interpretability, ethical considerations, while discussing solutions emphasizing importance rigorous validation. By providing a analysis for researchers clinicians, this underscores indispensable combating usher new era medical breakthroughs, ultimately aiming improve outcomes life.

Язык: Английский

Процитировано

1

A-to-I-edited miR-1251-5p restrains tumor growth and metastasis in lung adenocarcinoma through regulating TCF7-mediated Wnt signaling pathway DOI Creative Commons

Shuhua Xu,

Zhou Guoping,

Qiyu He

и другие.

Discover Oncology, Год журнала: 2024, Номер 15(1)

Опубликована: Окт. 24, 2024

RNA editing from A (adenine nucleotide) to I (hypoxanthine mediated by ADARs has attracted more and attention as an important post-transcriptional processing method. This research investigates the regulatory mechanism of A-to-I-edited miR-1251-5p in lung adenocarcinoma (LUAD).

Язык: Английский

Процитировано

0