Co-microencapsulation of Lactobacillus paracasei and Inonotus obliquus polysaccharide in alginate system: physicochemical and functional properties
Food Hydrocolloids,
Год журнала:
2025,
Номер
unknown, С. 111344 - 111344
Опубликована: Март 1, 2025
Язык: Английский
Positive nutritional selection of adults with healthy lifestyle and high daily fiber consumption for the isolation of beneficial intestinal bacteria: the iTARGET cohort study protocol.
A. Caillé,
Chloé Connan,
Noelle Lyon Belgy
и другие.
MethodsX,
Год журнала:
2025,
Номер
unknown, С. 103268 - 103268
Опубликована: Март 1, 2025
Recent
advances
in
the
study
of
gut
microbiota
has
pointed
to
its
under-utilized
source
potentially
beneficial
bacteria,
known
as
next
generation
probiotics,
offering
a
promising
avenue
restore
or
compensate
impaired
toward
healthy
state.
Aside
from
difficulties
achieve
in-lab
adequate
culture
conditions,
use
bacterial
isolates
is
also
limited
by
their
bioavailability
donor
itself.
In
iTARGET
study,
we
positively
selected
donors
based
on
diet
enriched
fiber,
that
been
shown
increase
prevalence
species
associated
with
health.
The
monocenter,
prospective,
observational
adults
lifestyle
and
high
daily
fiber
consumption.
We
aim
recruit
individuals
two
phases,
first
one
for
all
will
permit
identification
carriers
bacteria
interest
second
phase
subset
allow
isolation
previously
identified
bacteria.
Our
primary
outcome
at
least
isolate.
secondary
outcomes
comprised
throughput
metagenomic
profiles
intestinal
characterization
cultured
isolates.
was
approved
French
Research
Ethics
Committees
(Comité
de
Protection
des
Personnes
Sud-Est
I)
under
National
reference
ID
2023-A01677-38.
Study
findings
results
be
published
peer-reviewed
Open
Access
journals.
(Trial
registration
number
ClinicalTrials.gov:
NCT06166810).
Язык: Английский
Editorial overview: Pioneering innovations in food biotechnology
Current Opinion in Biotechnology,
Год журнала:
2025,
Номер
93, С. 103300 - 103300
Опубликована: Март 27, 2025
Язык: Английский
Next-Generation Probiotics and Chronic Diseases: A Review of Current Research and Future Directions
Journal of Agricultural and Food Chemistry,
Год журнала:
2024,
Номер
72(50), С. 27679 - 27700
Опубликована: Ноя. 26, 2024
The
burgeoning
field
of
microbiome
research
has
profoundly
reshaped
our
comprehension
human
health,
particularly
highlighting
the
potential
probiotics
and
fecal
microbiota
transplantation
(FMT)
as
therapeutic
interventions.
While
benefits
traditional
are
well-recognized,
efficacy
mechanisms
remain
ambiguous,
FMT's
long-term
effects
still
being
investigated.
Recent
advancements
in
high-throughput
sequencing
have
identified
gut
microbes
with
significant
health
benefits,
paving
way
for
next-generation
(NGPs).
These
NGPs,
engineered
through
synthetic
biology
bioinformatics,
designed
to
address
specific
disease
states
enhanced
stability
viability.
This
review
synthesizes
current
on
NGP
stability,
challenges
delivery,
their
applications
preventing
treating
chronic
diseases
such
diabetes,
obesity,
cardiovascular
diseases.
We
explore
physiological
characteristics,
safety
profiles,
action
various
strains
while
also
addressing
opportunities
presented
by
integration
into
clinical
practice.
NGPs
revolutionize
microbiome-based
therapies
improve
outcomes
is
immense,
underscoring
need
further
optimize
ensure
safety.
Язык: Английский