Vagus nerve stimulation for the treatment of narcolepsy DOI Creative Commons
Yaroslav Winter, Katharina Sandner, Claudio L. Bassetti

и другие.

Brain stimulation, Год журнала: 2024, Номер 17(1), С. 83 - 88

Опубликована: Янв. 1, 2024

No study on neurostimulation in narcolepsy is available until now. Arousal- and wake-promoting effects of vagus nerve stimulation (VNS) have been demonstrated animal experiments are well-known as side VNS therapy epilepsy depression. The objective was to evaluate the therapeutic effect daily sleepiness cataplexies narcolepsy. In our open-label prospective comparative study, we included patients who were treated with because depression or compared them controls without for (18 each group, aged 31.5 ± 8.2 years). We evaluated (Epworth Sleepiness Scale, ESS) number per week before implantation at three six month follow-ups. Compared baseline (ESS: 15.9 2.5) showed a significant improvement ESS after months (11.2 3.3, p < 0.05) (9.6 2.8, 0.001) trend reduction cataplexies. ESS-improvement observed (14.9 3.9, 13.6 3.7, 13.2 3.5, = 0.2 baseline, months, correspondingly). Side did not differ between groups. this first evaluation narcolepsy, found due type neurostimulation. could be promising non-medical treatment

Язык: Английский

Vagus Nerve Stimulation in Ischemic Stroke DOI
Sasan Andalib, Afshin A. Divani, Cenk Ayata

и другие.

Current Neurology and Neuroscience Reports, Год журнала: 2023, Номер 23(12), С. 947 - 962

Опубликована: Ноя. 27, 2023

Язык: Английский

Процитировано

18
Do the therapeutic effects of psilocybin involve actions in the gut? DOI

Felicia Reed,

Claire J. Foldi

Trends in Pharmacological Sciences, Год журнала: 2024, Номер 45(2), С. 107 - 117

Опубликована: Янв. 11, 2024

Язык: Английский

Процитировано

8
Transcutaneous auricular vagus nerve stimulation improves anxiety symptoms and cortical activity during verbal fluency task in Parkinson's disease with anxiety DOI
Heng Zhang,

Aidi Shan,

Chenhui Wan

и другие.

Journal of Affective Disorders, Год журнала: 2024, Номер 361, С. 556 - 563

Опубликована: Июнь 24, 2024

Язык: Английский

Процитировано

7
Current challenges in reliably targeting the noradrenergic locus coeruleus using transcutaneous auricular vagus nerve stimulation (taVNS) DOI
Mareike Ludwig, Christian Wienke, Matthew J. Betts

и другие.

Autonomic Neuroscience, Год журнала: 2021, Номер 236, С. 102900 - 102900

Опубликована: Окт. 29, 2021

Язык: Английский

Процитировано

33
Vagus nerve stimulation for the treatment of narcolepsy DOI Creative Commons
Yaroslav Winter, Katharina Sandner, Claudio L. Bassetti

и другие.

Brain stimulation, Год журнала: 2024, Номер 17(1), С. 83 - 88

Опубликована: Янв. 1, 2024

No study on neurostimulation in narcolepsy is available until now. Arousal- and wake-promoting effects of vagus nerve stimulation (VNS) have been demonstrated animal experiments are well-known as side VNS therapy epilepsy depression. The objective was to evaluate the therapeutic effect daily sleepiness cataplexies narcolepsy. In our open-label prospective comparative study, we included patients who were treated with because depression or compared them controls without for (18 each group, aged 31.5 ± 8.2 years). We evaluated (Epworth Sleepiness Scale, ESS) number per week before implantation at three six month follow-ups. Compared baseline (ESS: 15.9 2.5) showed a significant improvement ESS after months (11.2 3.3, p < 0.05) (9.6 2.8, 0.001) trend reduction cataplexies. ESS-improvement observed (14.9 3.9, 13.6 3.7, 13.2 3.5, = 0.2 baseline, months, correspondingly). Side did not differ between groups. this first evaluation narcolepsy, found due type neurostimulation. could be promising non-medical treatment

Язык: Английский

Процитировано

5