Trends in Parasitology, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
Язык: Английский
Nature Communications, Год журнала: 2024, Номер 15(1)
Опубликована: Фев. 8, 2024
Abstract West Nile virus (WNV) is an emerging mosquito-borne pathogen in Europe where it represents a new public health threat. While climate change has been cited as potential driver of its spatial expansion on the continent, formal evaluation this causal relationship lacking. Here, we investigate extent to which WNV can be attributed while accounting for other direct human influences such land-use and population changes. To end, trained ecological niche models predict risk local circulation leading cases then unravel isolated effect by comparing factual simulations counterfactual based same environmental changes but long-term trends have removed. Our findings demonstrate notable increase area ecologically suitable during period 1901–2019, whereas remains largely unchanged no-climate-change counterfactual. We show that drastic at exposure partly due historical density, also critical behind heightened Europe.
Язык: Английский
Процитировано
39
One Health, Год журнала: 2023, Номер 16, С. 100490 - 100490
Опубликована: Янв. 20, 2023
Mosquitoes are vectors for emerging and re-emerging infectious viral diseases of humans, livestock other animals. In addition to these arthropod-borne (arbo)viruses, mosquitoes host an array insect-specific viruses, collectively referred as the mosquito virome. Mapping virome understanding if how its composition modulates arbovirus transmission is critical understand arboviral disease emergence outbreak dynamics. recent years, next-generation sequencing well PCR culture-based methods have been extensively used identify mosquito-associated providing insights into virus ecology evolution. Until now, large amount data, specifically those acquired by metagenomic sequencing, has not comprehensively integrated. We constructed a searchable database viruses associated with vector from 175 studies, published between October 2000 February 2022. most frequently detected widespread Culex, Aedes Anopheles genera report their global distribution. addition, we highlight challenges extracting integrating data propose that standardized reporting format will facilitate interpretation re-use scientists. expect our comprehensive database, summarizing collected over 20 be useful resource future studies.
Язык: Английский
Процитировано
32
Parasites & Vectors, Год журнала: 2023, Номер 16(1)
Опубликована: Авг. 17, 2023
Biological invasions have increased significantly with the tremendous growth of international trade and transport. Hematophagous arthropods can be vectors infectious potentially lethal pathogens parasites, thus constituting a growing threat to humans-especially when associated biological invasions. Today, several major vector-borne diseases, currently described as emerging or re-emerging, are expanding in world dominated by climate change, land-use change intensive transportation humans goods. In this review, we retrace historical trajectory these better understand their ecological, physiological genetic drivers impacts on ecosystems human health. We also discuss arthropod management strategies mitigate future risks harnessing ecology, public health, economics social-ethnological considerations. Trade transport goods materials, including vertebrate introductions worn tires, historically been important introduction pathways for most prominent invasive hematophagous arthropods, but sources likely diversify globalization. Burgeoning urbanization, urban heat island effect interact favor diseases they vector. To novel disease outbreaks, stronger preventative monitoring transboundary surveillance measures urgently required. Proactive approaches, such use engagement citizen science, would reduce epidemiological ecological could save millions lives billions dollars spent control management. Last, our capacities manage sustainable way worldwide improved promoting interactions among experts health sector, stakeholders environmental issues policymakers (e.g. One Health approach) while considering wider social perceptions.
Язык: Английский
Процитировано
31
Parasites & Vectors, Год журнала: 2024, Номер 17(1)
Опубликована: Фев. 29, 2024
Abstract Background Culex pipiens sensu stricto (s.s.) is considered the primary vector of Usutu virus and West Nile virus, consists two morphologically identical but behaviourally distinct biotypes ( Cx. biotype molestus) their hybrids. Both are expected to differ in feeding behaviour, pipiens/molestus hybrids presumed display intermediate behaviour. However, evidence for patterns scarce, date no studies have related differences host abundance. Methods Mosquitoes were collected using CO 2 -baited traps. We blood-engorged pipiens/torrentium specimens from 12 contrasting urban sites, namely six city parks residential areas. Blood engorged mosquitoes identified species biotype/hybrid level via real-time polymerase chain reaction (PCR). performed blood meal analysis PCR Sanger sequencing. Additionally, avian communities surveyed vocal sounds and/or visual observation. Results selected 64 which we successfully determined origin 55 specimens. Of these, 38 belonged , 14 identity three could not be determined. No molestus or torrentium collected. observed between across different habitats. Avian community composition differed areas, whereas overall abundance did habitat types. Conclusions Our results show following: (1) s.s. regardless whether individuals as (2) detected availability (3) that both types, fed on mammalian hosts. This underscores potential role arbovirus transmission Graphical
Язык: Английский
Процитировано
13
bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2025, Номер unknown
Опубликована: Янв. 28, 2025
Abstract Understanding how life is adapting to urban environments represents an important challenge in evolutionary biology. Here we investigate a widely cited example of adaptation, Culex pipiens form molestus , also known as the London Underground Mosquito. Population genomic analysis ∼350 contemporary and historical samples counter popular hypothesis that originated belowground less than 200 years ago. Instead, show first adapted human aboveground Middle East over course >1000 years, likely concert with rise agricultural civilizations. Our results highlight role early society priming taxa for evolution have implications understanding arbovirus transmission.
Язык: Английский
Процитировано
1
PLOS Climate, Год журнала: 2023, Номер 2(5), С. e0000129 - e0000129
Опубликована: Май 1, 2023
West Nile virus (WNV) is an arbovirus with a wide geographical distribution. It maintained in enzootic bird-mosquito cycle and exhibits regular zoonotic transmission to humans, whom it can cause fever neuroinvasive disease. Over the last decades, WNV has emerged as serious health threat profound impacts on animal human health. broadly accepted that climate change of through multiple pathways via its vectors, pathogen, hosts, environment. Although some clarity been established, outcomes these climate-driven processes are yet be better understood before they fully benefit tailored prevention control measures. This review focuses eco-epidemiology how impacted by integrative lens. We discuss role eco-epidemiological modeling knowledge generation highlight importance adopting interdisciplinary transdisciplinary One Health approach for improved surveillance, data collection, modeling, translation into actionable policy control.
Язык: Английский
Процитировано
23
Proceedings of the Royal Society B Biological Sciences, Год журнала: 2024, Номер 291(2018)
Опубликована: Март 13, 2024
Mathematical models within the Ross–Macdonald framework increasingly play a role in our understanding of vector-borne disease dynamics and as tools for assessing scenarios to respond emerging threats. These threats are typically characterized by high degree heterogeneity, introducing range possible complexities challenges maintain link with empirical evidence. We systematically identified analysed total 77 published papers presenting compartmental West Nile virus (WNV) that use parameter values derived from studies. Using set 15 criteria, we measured dissimilarity compared framework. also retrieved purpose type traced sources their parameters. Our review highlights increasing refinements WNV models. Models prediction included highest number refinements. found uneven distributions evidence values. several parametrizing such complex For parameters common most models, synthesize ranges. The study potential improve quality applicability policy establishing closer collaboration between mathematical modelling work.
Язык: Английский
Процитировано
8
Parasites & Vectors, Год журнала: 2024, Номер 17(1)
Опубликована: Фев. 19, 2024
Abstract Background Mosquitoes of the Culex pipiens complex are widely distributed vectors for several arboviruses affecting humans. Consequently, their populations have long been controlled using insecticides, in response to which different resistance mechanisms selected. Moreover, ecological preferences and broad adaptability allow C. mosquitoes breed highly polluted water bodies where they exposed many residuals from anthropogenic activities. It has observed mosquito species that anthropization (in particular urbanization agricultural lands) can lead increased exposure insecticides thus resistance. The main objective present study was investigate whether how and/or lands had a similar impact on Morocco. Methods Breeding sites were sampled along transects four regions around major Moroccan cities, following gradients decreasing anthropization. imprint activities evaluated each site as percentage areas classified three categories: urban, natural. We then assessed frequencies known alleles these samples followed dynamics five urban breeding over 4 years. Results distribution revealed strong anthropization, both urbanized lands, although between mutations regions; we did not find any clear trend during survey. Conclusions Our provides further evidence role anthropic selection maintenance selected mosquitoes. consequences worrying this could decrease vector control capacities result epizootic epidemic outbreaks. concerted integrated disease strategies must be designed include better management regarding our Graphical
Язык: Английский
Процитировано
7
Viruses, Год журнала: 2023, Номер 15(2), С. 366 - 366
Опубликована: Янв. 27, 2023
Viral infections caused by viruses from the family Flaviviridae such as Zika (ZIKV), Dengue (DENV), yellow fever (YFV), tick-borne encephalitis (TBEV), West Nile (WNV), and Usutu (USUV) are some of most challenging diseases for recognition in clinical diagnostics epidemiological tracking thanks to their short viremia, non-specific symptoms, high cross-reactivity observed laboratory techniques. In Central Europe, relevant endemic flaviviruses mosquito-borne WNV USUV, TBEV. All three have been recognised be responsible human neuroinvasive diseases. Moreover, they interrupting blood transplantation safety processes, when great efforts made save a patient’s life could defeated acquired infection donors. Due trend changing distribution abundance vectors influenced global change, co-circulation WNV, TBEV can same area. this perspective, we discuss problems flavivirus epidemiology monitoring Slovakia model area where zone has recently detected. This new situation presents multiple challenges not only or surveillance but particularly also organ safety. We conclude that current routinely used donor screening applied European Union (EU) regulations out date novel methods which become available recent years, e.g., next-gene sequencing urine should implemented immediately.
Язык: Английский
Процитировано
14
Trends in Parasitology, Год журнала: 2024, Номер 40(8), С. 744 - 762
Опубликована: Июль 16, 2024
The nudiviruses (family: Nudiviridae) are large double-stranded DNA (dsDNA) viruses that infect insects and crustaceans, have most recently been identified from ectoparasitic members (fleas lice). This virus family was created in 2014 has since expanded via the discovery of multiple novel viral candidates or accepted members, sparking need for a new taxonomic evolutionary overview. Using current information (including data public databases), we construct comprehensive phylogeny, encompassing 49 different nudiviruses. We use this phylogeny to propose structure Nudiviridae by suggesting two genera (Zetanudivirus Etanudivirus), lice. detail emerging relationships between their hosts, considering history ecological role.
Язык: Английский
Процитировано
6