Neuroscience: Reliable and refined motion computations in the retina

Current Biology, Год журнала: 2022, Номер 32(10), С. R474 - R476

Опубликована: Май 1, 2022

Язык: Английский

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Robust and efficient representations of dynamic stimuli in hierarchical neural networks via temporal smoothing

Frontiers in Computational Neuroscience, Год журнала: 2023, Номер 17

Опубликована: Июнь 15, 2023

Introduction Efficient coding that minimizes informational redundancy of neural representations is a widely accepted principle. Despite the benefit, maximizing efficiency in can make representation vulnerable to random noise. One way achieve robustness against noise smoothening responses. However, it not clear whether smoothness responses hold robust when dynamic stimuli are processed through hierarchical brain structure, which only but also systematic error due temporal lag be induced. Methods In present study, we showed via spatio-temporally efficient both and by effectively dealing with delay visual hierarchy processing stimuli. Results The simulation results demonstrated network whose bidirectional synaptic connections were learned natural scenes could elicit moving bars similar those static identical position orientation, indicating erroneous information. It implies preserves structure environments locally structures. Discussion suggest importance balance between for across

Язык: Английский

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Asymmetric retinal direction tuning predicts optokinetic eye movements across stimulus conditions

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2022, Номер unknown

Опубликована: Июнь 13, 2022

ABSTRACT Across species, the optokinetic reflex (OKR) stabilizes vision during self-motion. OKR occurs when ON direction-selective retinal ganglion cells (oDSGCs) detect slow, global image motion on retina. How oDSGC activity is integrated centrally to generate behavior remains unknown. Here, we discover mechanisms that contribute encoding in vertically-tuned oDSGCs, and leverage these findings empirically define signal transformation between output vertical behavior. We demonstrate oDSGCs contrast-sensitive asymmetric for types prefer opposite directions. These phenomena arise from interplay spike threshold nonlinearities differences synaptic input weights, including shifts balance of excitation inhibition. In behaving mice, neurophysiological observations, along with a central subtraction outputs, accurately predict trajectories across stimulus conditions. Thus, tuning competing sensory channels can critically shape

Язык: Английский

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