Synaptic logistics: Competing over shared resources DOI Creative Commons
Anne-Sophie Hafner, Jochen Triesch

Molecular and Cellular Neuroscience, Год журнала: 2023, Номер 125, С. 103858 - 103858

Опубликована: Май 10, 2023

High turnover rates of synaptic proteins imply that synapses constantly need to replace their constituent building blocks. This requires sophisticated supply chains and potentially exposes shortages as they compete for limited resources. Interestingly, competition in neurons has been observed at different scales. Whether it is receptors binding sites inside a single synapse or fighting resources grow. Here we review the implications such function plasticity. We identify multiple mechanisms use safeguard themselves against fundamental neurologistic trade-off governing sizes reserve pools essential

Язык: Английский

Synaptic logistics: Competing over shared resources DOI Creative Commons
Anne-Sophie Hafner, Jochen Triesch

Molecular and Cellular Neuroscience, Год журнала: 2023, Номер 125, С. 103858 - 103858

Опубликована: Май 10, 2023

High turnover rates of synaptic proteins imply that synapses constantly need to replace their constituent building blocks. This requires sophisticated supply chains and potentially exposes shortages as they compete for limited resources. Interestingly, competition in neurons has been observed at different scales. Whether it is receptors binding sites inside a single synapse or fighting resources grow. Here we review the implications such function plasticity. We identify multiple mechanisms use safeguard themselves against fundamental neurologistic trade-off governing sizes reserve pools essential

Язык: Английский

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