Mental health: The REM sleep paradox in depression DOI
Emi Hasegawa, Michael Lazarus

Current Biology, Год журнала: 2024, Номер 34(15), С. R739 - R741

Опубликована: Авг. 1, 2024

Язык: Английский

A small population of stress-responsive neurons in the hypothalamus-habenula circuit mediates development of depression-like behavior in mice DOI
Zhi-Wei Zheng,

Yiqin Liu,

Ruiqi Mu

и другие.

Neuron, Год журнала: 2024, Номер unknown

Опубликована: Окт. 1, 2024

Язык: Английский

Процитировано

5
The Role of Sleep Quality in Mediating the Relationship Between Habenula Volume and Resilience DOI
Qi Dai, Yusuke Kyuragi, Halwa Zakia

и другие.

Psychiatry Research, Год журнала: 2025, Номер 344, С. 116358 - 116358

Опубликована: Янв. 9, 2025

Язык: Английский

Процитировано

0
Slumber under pressure: REM sleep and stress response DOI
Bernhard Schaefke,

Jingfei Li,

Binghao Zhao

и другие.

Progress in Neurobiology, Год журнала: 2025, Номер unknown, С. 102771 - 102771

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0
Potassium Release From the Habenular Astrocytes Induces Depressive‐Like Behaviors in Mice DOI Creative Commons
Hidenori Aizawa,

Miho Matsumata,

Laura Ayaka Noguera Oishi

и другие.

Glia, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 29, 2024

ABSTRACT The habenula has been implicated in psychiatric disorders such as depression, primarily because of its role the modulation dopaminergic and serotonergic systems, which play a pathophysiology these disorders. Despite growing evidence supporting behavioral regulation, process by neural cells develop remains elusive. Since habenular anlage is found prosomere 2 domain expressing transcription factor Dbx1 mouse embryos, we hypothesized that Dbx1‐expressing source astrocytes modulate neuronal activity habenula. To address this, examined cell lineage generated from male mice using tamoxifen‐inducible Cre recombinase under control promoter. Perinatal induction labeled migrating radially ventricular zone to pial side anlage, eventually showed astrocyte‐like morphology with expression marker protein, S100β, for mature adult mouse. Photostimulation ChR2 released potassium ions into extracellular space, turn excited neurons an increased firing rate lateral Finally, photostimulation exacerbated depression‐like phenotypes reduced locomotor activity, exaggerated despair behavior impaired sucrose preference open‐field, tail suspension tests, respectively. These results indicated perinatal modulated via regulation levels.

Язык: Английский

Процитировано

1
Mental health: The REM sleep paradox in depression DOI
Emi Hasegawa, Michael Lazarus

Current Biology, Год журнала: 2024, Номер 34(15), С. R739 - R741

Опубликована: Авг. 1, 2024

Язык: Английский

Процитировано

0