Background:
Exposure
to
adversity
in
childhood
is
a
risk
factor
for
lifetime
mental
health
problems.
Altered
pace
of
biological
ageing,
as
measured
through
pubertal
timing,
one
potential
explanatory
mechanism
this
risk.
This
study
examined
whether
timing
mediated
the
association
between
(threat
and
deprivation)
adolescent
problems
(internalizing
externalizing),
was
moderated
by
sex.
Methods:
Aims
were
using
Adolescent
Brain
Cognitive
Development
Study,
large
population
representative
sample
from
United
States.
Data
used
three
timepoints
across
ages
9-
14-
years.
Latent
scores
confirmatory
analysis
operationalized
exposure
threat
deprivation.
Bayesian
mixed-effects
regression
models
tested
early
adolescence
effects
on
later
internalizing
externalizing
Sex
moderator
pathway.
Results:
Both
deprivation
associated
with
symptoms.
Threat,
but
not
deprivation,
earlier
which
differences
only
observed
direct
problems,
no
such
present
mediating
pathways.
Conclusions:
Adversity
had
similar
ageing
(as
indexed
timing)
males
females.
However,
impact
appears
depend
dimension
experienced,
increasing
timing.
Journal of Child Psychology and Psychiatry,
Год журнала:
2024,
Номер
65(4), С. 459 - 480
Опубликована: Фев. 23, 2024
Anhedonia,
or
diminished
pleasure
and
motivation,
is
a
symptom
of
severe
mental
illness
(e.g.,
depressive
disorder,
bipolar
schizophrenia)
that
emerges
during
adolescence.
Anhedonia
pernicious
related
to
social
impairments,
treatment
resistance,
suicide.
As
the
mechanisms
anhedonia
are
postulated
include
frontostriatal
circuitry
dopamine
neuromodulatory
system,
development
plasticity
these
systems
vulnerable
period
adolescence,
as
well
their
sensitivity
pubertal
hormones,
suggest
maturation
could
play
role
in
anhedonia.
This
review
takes
developmental
perspective,
considering
possibility
context
adolescent
development,
with
childhood
adversity
chronic
inflammation
influencing
neural
reward
accelerate
anhedonia's
progression.
Here,
we
relevant
extant
literature
on
components
this
model
directions
for
future
research.
Journal of Social and Personal Relationships,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 12, 2025
Peer
victimization
and
dating
violence
are
associated
with
poor
psychosocial
adjustment.
However,
possible
gender
differences
in
victimized
adolescents
both
contexts
have
not
been
explored.
This
study
aims
to
analyze
how
types
of
related
five
indicators
adjustment
(depressed
mood,
life
satisfaction,
psychological
distress,
social
network
evaluation
loneliness),
considering
differences.
From
an
initial
sample
1078
adolescents,
672
(51.64%
girls)
aged
between
12–19
(
M
=
14.45;
SD
1.62)
participated.
The
results
showed
that
relational
(peers
partner)
had
poorer
than
those
only
one
context,
this
difference
being
greater
for
girls
boys.
In
addition,
some
were
obtained
the
each
type
victimization.
Depressed
loneliness
significant
positive
predictors
peer
boys
girls.
Nevertheless,
predicted
boys,
but
girls,
while
satisfaction
a
predictive
capacity
These
findings
highlight
existence
should
be
considered
design
intervention
programs
effectiveness.
Scientific Reports,
Год журнала:
2025,
Номер
15(1)
Опубликована: Май 21, 2025
Abstract
Black
and
Latinx
youth
experience
earlier
pubertal
timing
relative
to
their
non-stigmatized
peers.
Research
on
determinants
of
this
increased
risk
has
largely
focused
aspects
individuals
(e.g.,
body
mass
index)
or
proximal
environment
socioeconomic
status),
the
exclusion
broader
macro-social
factors.
Using
2
years
Adolescent
Brain
Cognitive
Development
Study
®
data,
we
examined
whether
structural
stigma
state-level
policies,
aggregated
prejudicial
attitudes)
was
associated
with
hormonal
physical
markers
development.
Baseline
results
documented
among
girls
(hormones)
boys
(youth
and/or
caregiver
report)
in
states
higher
(vs.
lower)
levels
racism
xenophobia,
respectively.
Observed
associations
were
comparable
effect
size
a
well-established
correlate
development,
index,
remained
1
year
later
these
stigmatized
non-stigmatized)
groups.
Findings
suggest
need
broaden
study
development
include
Journal of Child Psychology and Psychiatry,
Год журнала:
2023,
Номер
65(8), С. 1037 - 1046
Опубликована: Дек. 29, 2023
Background
Exposure
to
adversity
early
in
life
(ELA)
has
been
associated
with
elevated
risk
for
depression
during
adolescence,
particularly
females;
the
mechanisms
underlying
this
association,
however,
are
poorly
understood.
One
potential
mechanism
linking
ELA
and
sex
differences
depressive
symptoms
is
sleep
disturbances,
which
increase
adolescence
more
common
females.
Here,
we
examined
whether
disturbances
mediate
association
between
increases
mediation
differs
by
sex.
Methods
224
(
N
=
132
females)
youth
were
recruited
at
age
9–13
years
assessed
every
2
across
three
timepoints.
At
first
timepoint,
conducted
extensive
interviews
about
stressful
events
participants
experienced;
provided
subjective
severity
ratings
of
objectively
scored
each
event.
Self‐reported
all
We
linear
mixed
models
estimate
both
initial
levels
changes
symptoms,
moderated
analyses
test
and/or
mediated
(objective
subjective)
mediations
differed
Results
While
higher
problems
uniquely
males
females,
they
related
differently
For
greater
(both
subjectively
rated)
was
problems,
turn
from
late
adolescence.
In
contrast,
males,
exposure
not
either
of,
or
in,
problems.
Conclusions
These
findings
highlight
role
transition
mediating
effects
on
symptoms.
Psychological Medicine,
Год журнала:
2024,
Номер
unknown, С. 1 - 9
Опубликована: Сен. 9, 2024
Abstract
Background
Fear
learning
is
a
core
component
of
conceptual
models
how
adverse
experiences
may
influence
psychopathology.
Specifically,
existing
theories
posit
that
childhood
involving
trauma
are
associated
with
altered
fear
processes,
while
deprivation
not.
Several
studies
have
found
acquisition
in
youth
exposed
to
trauma,
but
not
deprivation,
although
the
specific
patterns
varied
across
studies.
The
present
study
utilizes
longitudinal
sample
children
variability
adversity
examine
associations
among
learning,
and
psychopathology
youth.
Methods
includes
170
youths
aged
10–13
years
(
M
=
11.56,
s.d.
0.47,
48.24%
female).
Children
completed
conditioning
task
skin
conductance
responses
(SCR)
were
obtained,
which
included
both
extinction.
Childhood
severity
measured
using
parent
report.
Symptoms
anxiety,
externalizing
problems,
post-traumatic
stress
disorder
(PTSD)
assessed
at
baseline
again
two-years
later.
Results
Greater
trauma-related
greater
SCR
threat
cue
(CS+)
relative
safety
(CS−)
early
acquisition,
controlling
for
age,
sex.
Deprivation
was
unrelated
learning.
during
increased
PTSD
symptoms
over
time
mediated
relationship
between
prospective
changes
symptoms.
Conclusions
youth,
be
one
mechanism
linking
exposure
violence
emergence
adolescence.
Psychological Medicine,
Год журнала:
2023,
Номер
53(16), С. 7655 - 7665
Опубликована: Июнь 2, 2023
Abstract
Background
Undergoing
puberty
ahead
of
peers
(‘earlier
pubertal
timing’)
is
an
important
risk
factor
for
mental
health
problems
during
early
adolescence.
The
current
study
examined
pathways
between
timing
and
via
connectivity
neural
systems
implicated
in
emotional
reactivity
regulation
(specifically
corticolimbic
connections)
9-
to
14-year-olds.
Method
Research
questions
were
the
Adolescent
Brain
Cognitive
Development
(ABCD)
Study,
a
large
population
representative
sample
United
States.
Linear
mixed
models
associations
resting-state
connectivity.
Significant
connections
as
potential
mediators
relationship
(withdrawn
depressed
rule-breaking)
problems.
Exploratory
analyses
interrogated
whether
family
environment
moderated
patterns
those
undergoing
earlier
than
their
peers.
Results
Earlier
was
related
decreased
limbic
structures
(bilateral
amygdala
right
hippocampus)
cingulo-opercular
network,
left
somatomotor
(mouth)
well
hippocampus
ventral
attention
network
visual
network.
Corticolimbic
also
mediated
increased
withdrawn
(but
not
rule-breaking
problems).
Finally,
parental
acceptance
buffered
against
that
Conclusion
Findings
highlight
role
mediating
problems,
we
present
preliminary
evidence
may
buffer
these
Journal of Child Psychology and Psychiatry,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 31, 2024
Background
The
mechanisms
linking
early‐life
adversity
with
psychopathology
over
the
life‐course
are
complex.
In
this
prospective
study,
we
collectively
examined
cognitive,
affective,
and
developmental
mediators
previously
found
to
individually
link
childhood
threat
deprivation
experiences
adolescent
identify
most
potent
mechanisms.
Methods
Data
came
from
a
community
sample
of
227
children
(mean
child
age
11.5
±
0.5
years,
48.5%
female)
Seattle
metro
area
recruitment
designed
reflect
diversity
in
family
income.
Candidate
included
self‐rated
pubertal
development
task‐measured
attention
bias
threat,
emotion
regulation,
theory
mind,
fear
learning,
inhibitory
control,
language
ability,
reasoning,
reward
sensitivity.
Using
high‐dimensional
mediation
approach,
determined
which
mediating
pathways
persisted
after
controlling
for
all
candidate
associated
psychopathology.
Models
additionally
controlled
child's
age,
sex,
early‐childhood
emotional
behavioral
symptoms,
poverty,
maternal
depression.
Results
Blunted
sensitivity
mediated
relationship
between
internalizing
psychopathology,
explaining
17.25%
(95%
CI
1.08%,
69.96%)
association.
Advanced
was
increases
externalizing
symptoms
(standardized
associations
0.16
0.03,
0.29)
0.17
0.05,
0.29),
respectively),
but
not
adversity.
Although
strongly
related
no
were
empirically
identified.
Conclusions
well‐characterized
sample,
isolated
as
robust
mediator
association
Interventions
aimed
at
bolstering
may
mitigate
impact
on
problems.
