Unraveling the role of muscle mass and strength in predicting type 2 diabetes risk: a systematic review
Acta Diabetologica,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 6, 2025
Язык: Английский
Unraveling the dual threat: sarcopenia and insufficient physical activity in diabetes risk
Frontiers in Endocrinology,
Год журнала:
2025,
Номер
15
Опубликована: Янв. 8, 2025
This
study
aimed
to
investigate
the
alterations
in
diabetes
risk
associated
with
sarcopenia
and
insufficient
physical
activity,
as
well
demographic
shifts
within
diabetic
population.
Utilizing
pertinent
data
from
National
Health
Nutrition
Examination
Survey
(NHANES)
database
spanning
2011
2018,
criteria
for
were
established
by
Foundation
Institutes
of
Health.
These
calculated
using
lean
body
mass
conjunction
index
data.
Physical
activity
levels
assessed
PAQ
questionnaire
NHANES
database.
The
presence
was
determined
through
DIQ
laboratory
examination
analysis
performed
multivariable
logistic
regression.
prevalence
both
population
188%
greater
than
non-diabetic
Sarcopenia
positively
correlated
an
increased
onset,
demonstrating
a
1.45-fold
heightened
when
conditions
present
(OR=2.45,95%CI,1.35-4.44,P<0.05).
combined
effect
significantly
alone
(OR=1.84,95%CI,1.09-3.11,P<0.05)
or
(OR=1.55,95%CI,1.11-2.15,P<0.05).
A
synergistic
relationship
exists
between
resulting
markedly
elevated
are
concurrently.
Therefore,
comprehensive
management
strategies
should
prioritize
populations
exhibiting
activity.
Язык: Английский
Regional adipose distribution and metabolically unhealthy phenotype in Chinese adults: evidence from China National Health Survey
Environmental Health and Preventive Medicine,
Год журнала:
2025,
Номер
30(0), С. 5 - 5
Опубликована: Янв. 1, 2025
The
mechanisms
distinguishing
metabolically
healthy
from
unhealthy
phenotypes
within
the
same
BMI
categories
remain
unclear.
This
study
aimed
to
investigate
associations
between
regional
fat
distribution
and
in
Chinese
adults
across
different
categories.
cross-sectional
involving
11833
aged
20
years
older.
Covariance
analysis,
adjusted
for
age,
compared
percentage
of
(trunk,
leg,
or
arm
divided
by
whole-body
fat)
participants.
Trends
with
number
metabolic
abnormalities
were
assessed
Jonckheere-Terpstra
test.
Odds
ratios
(ORs)
their
95%
confidence
intervals
(CIs)
estimated
logistic
regression
models.
All
analyses
performed
separately
sex.
In
non-obese
individuals,
participants
exhibited
higher
percent
trunk
lower
leg
Additionally,
increased
decreased
abnormalities.
After
adjustment
demographic
lifestyle
factors,
as
well
BMI,
was
associated
odds
being
[highest
vs.
lowest
quartile:
ORs
(95%CI)
1.64
(1.35,
2.00)
men
2.00
(1.63,
2.46)
women].
Conversely,
quartile,
phenotype
highest
quartile
0.64
(0.53,
0.78)
0.60
(0.49,
0.74)
men,
0.72
(0.56,
0.93)
0.46
(0.36,
0.59)
women,
respectively.
Significant
interactions
observed
both
sexes,
stronger
found
individuals
normal
weight
overweight.
Trunk
is
a
risk
phenotype,
while
are
protective
factors.
Regional
assessments
crucial
identifying
phenotypes,
particularly
individuals.
Язык: Английский
Crosstalk between microRNA and inflammation; critical regulator of diabetes
Experimental Cell Research,
Год журнала:
2025,
Номер
447(1), С. 114507 - 114507
Опубликована: Март 7, 2025
Язык: Английский
The effect of sarcopenic obesity on glycaemic status based on fasting plasma glucose and glycated haemoglobin: A prospective cohort study
Diabetes Obesity and Metabolism,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 21, 2024
Abstract
Aim
To
investigate
the
effect
of
sarcopenic
obesity
on
progression
glycaemic
status
in
middle‐aged
and
older
adults
without
diabetes.
Materials
Methods
This
research
involved
4637
participants
diabetes
from
China
Health
Retirement
Longitudinal
Study
2011–2015.
Sarcopenic
at
baseline
was
evaluated
based
Asian
Working
Group
for
Sarcopenia
2019
criteria.
According
to
American
Diabetes
Association
criteria,
we
used
fasting
plasma
glucose
glycated
haemoglobin
define
status.
Cox
proportional
hazard
models
were
applied
obtain
adjusted
ratios
(HRs)
95%
confidence
intervals
(CIs).
Results
The
mean
age
included
58.98
±
8.82
years,
45.35%
men.
During
18,497
person‐years
follow‐up,
1743
(37.59%)
cases
with
identified.
Compared
sarcopenia
obesity,
but
not
only
or
only,
exhibited
a
higher
risk
normoglycaemia
(HR
=
2.11;
CI:
1.10–4.04).
Moreover,
1.65;
1.04–2.63),
1.78;
1.11–2.86),
2.00;
1.29–3.12)
had
increased
prediabetes
Conclusions
may
be
more
pronounced
than
that
only.
Язык: Английский