Piezoelectric Chemosensors and Biosensors in Medical Diagnostics

Biosensors, Год журнала: 2025, Номер 15(3), С. 197 - 197

Опубликована: Март 20, 2025

This article explores the development and application of innovative piezoelectric sensors in point-of-care diagnostics. It highlights significance bedside tests, such as lateral flow electrochemical providing rapid accurate results directly at patient’s location. paper delves into principles assays, emphasizing their ability to detect disease-related biomarkers through mechanical stress-induced electrical signals. Various applications chemosensors biosensors are discussed, including use detection cancer biomarkers, pathogens, other health-related analytes. also addresses integration materials with advanced sensing technologies improve diagnostic accuracy efficiency, offering a comprehensive overview current advances future directions medical

Язык: Английский

Development and Clinical Evaluation of a Mpox Antigen-detecting Rapid Diagnostic Test

Journal of Virological Methods, Год журнала: 2025, Номер unknown, С. 115164 - 115164

Опубликована: Май 1, 2025

To address the global emergence of mpox after 2022 epidemic, a rapid and accurate diagnostic tool is needed at point care to identify individuals infected with virus (MPXV) prevent control spread virus. We designed an antigen-detecting test that exclusively detects MPXV without cross-reacting vaccinia by developing monoclonal antibodies against nuclear capsid protein A5L (MPXV-A5L). The results indicated detection limits were established 0.5ng/mL for MPXV-A5L 4.4 × 102 ~ 2.1 103 pfu/mL culture fluid. Clinical samples collected from patients showed high sensitivity 87% qPCR cycle threshold 25 or lower, specificity 100% tested negative in qPCR. ideal supporting clinical decision-making people suspected having infection resource-poor settings.

Язык: Английский

Usefulness of Point-of-Care Testing for Respiratory Viruses in a Pediatric Emergency Department Setting

Journal of Clinical Medicine, Год журнала: 2024, Номер 13(23), С. 7368 - 7368

Опубликована: Дек. 3, 2024

: Respiratory tract infections (RTIs) are a leading cause of pediatric emergency department (PED) visits, especially in children under five. These primarily viral, complicating diagnosis and management. This study assesses the impact point-of-care (POC) rapid diagnostic tests for respiratory viruses on clinical economic outcomes PED setting.

Язык: Английский