TrAC Trends in Analytical Chemistry, Год журнала: 2024, Номер 181, С. 118040 - 118040
Опубликована: Ноя. 8, 2024
Язык: Английский
TrAC Trends in Analytical Chemistry, Год журнала: 2024, Номер 181, С. 118040 - 118040
Опубликована: Ноя. 8, 2024
Язык: Английский
Microchemical Journal, Год журнала: 2024, Номер unknown, С. 111667 - 111667
Опубликована: Сен. 1, 2024
Язык: Английский
Процитировано
10Sensing and Bio-Sensing Research, Год журнала: 2025, Номер unknown, С. 100771 - 100771
Опубликована: Фев. 1, 2025
Язык: Английский
Процитировано
1Scientific Reports, Год журнала: 2025, Номер 15(1)
Опубликована: Май 15, 2025
Electrochemical surface plasmon resonance (ESPR) based biosensors play significant role in cancer detection due to its ability for real-time analysis and rapid detection. Herein, ESPR biosensor was designed employing three different coupling strategies the of biomarker α-fetoprotein (AFP), a liver biomarker. AFP antibody immobilized on gold coated glass sensor disk using viz. (i) 1-Ethyl-3-[3-dimethylaminopropyl] carbodiimide / N-hydroxy succinamide (EDC/NHS), (ii) ethylene diamine/ glutaraldehyde (EDA/GA) (iii) polyaniline/glutaraldehyde (PANI/GA) strategies. Among strategies, immobilization via EDA/GA strategy afforded highest sensitivity (28°/(ng/ml)) with reasonable linear range (0.5-3 ng/ml) whereas EDC/NHS wide (5-70 (2.12°/(ng/ml). Immobilization efficiency interaction steps involved construction were investigated by electrochemical impedance spectroscopy. The constructed validated quantifying human blood serum samples, where results are consistent values determined ELISA. This fundamental study can help researcher choose relevant achieving desired characteristics clinical biomarkers.
Язык: Английский
Процитировано
0TrAC Trends in Analytical Chemistry, Год журнала: 2024, Номер 181, С. 118040 - 118040
Опубликована: Ноя. 8, 2024
Язык: Английский
Процитировано
2