The application progress of cell membrane biomimetic nanoparticles in cancer diagnosis and treatment1

Progress in Biophysics and Molecular Biology, Год журнала: 2025, Номер unknown

Опубликована: Июнь 1, 2025

Язык: Английский

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Successful in vitro therapy of triple-negative breast cancer cells with cetuximab-encapsulated liposomes embedded in macrophage membrane

Particulate Science And Technology, Год журнала: 2025, Номер unknown, С. 1 - 11

Опубликована: Июнь 3, 2025

Язык: Английский

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Construction of biomimetic camouflaged neutrophil membrane nanoparticles for precise delivery and augmented glioma cancer treatment

Process Biochemistry, Год журнала: 2024, Номер 145, С. 229 - 242

Опубликована: Июнь 18, 2024

Язык: Английский

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Potential targets and applications of nanodrug targeting myeloid cells in osteosarcoma for the enhancement of immunotherapy

Frontiers in Pharmacology, Год журнала: 2023, Номер 14

Опубликована: Сен. 21, 2023

Targeted immunotherapies have emerged as a transformative approach in cancer treatment, offering enhanced specificity to tumor cells, and minimizing damage healthy tissues. The targeted treatment of the immune system has become clinically applicable, demonstrating significant anti-tumor activity both early late-stage malignancies, subsequently enhancing long-term survival rates. most frequent therapies for are executed through utilization checkpoint inhibitor antibodies chimeric antigen receptor T cell treatment. However, when using immunotherapeutic drugs or combined treatments solid tumors like osteosarcoma, challenges arise due limited efficacy induction severe cytotoxicity. Utilizing nanoparticle drug delivery systems target tumor-associated macrophages bone marrow-derived suppressor cells is promising attractive approach. This because these marrow often exert immunosuppressive effects microenvironment, promoting progression, metastasis, development resistance. Moreover, given propensity myeloid engulf nanoparticles microparticles, they logical therapeutic targets. Therefore, we discussed mechanisms nanomedicine-based enhancement therapy targeting how related strategies well adapt immunotherapy from perspectives such immunogenic death with nanoparticles, regulating proportion various cellular subgroups macrophages, interaction ligands, activating immunostimulatory signaling pathways, altering epigenetics, modulating intensity immunostimulation. We also explored clinical implementations grounded on nanomedicine.

Язык: Английский

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Preparation and characterization of edible pullulan/pectin nanofiber substrates and their digestion in simulated gastric and intestinal fluids

Industrial Crops and Products, Год журнала: 2023, Номер 206, С. 117745 - 117745

Опубликована: Ноя. 3, 2023

Язык: Английский

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