APPLICATION OF ANTIMICROBIAL PEPTIDES IN THE POULTRY INDUSTRY DOI
Letícia Ferreira Lima, Kamila Botelho Sampaio de Oliveira,

Karen Ofuji Osiro

и другие.

Veterinary Microbiology, Год журнала: 2024, Номер 298, С. 110267 - 110267

Опубликована: Сен. 27, 2024

Язык: Английский

Classical Simulations on Quantum Computers: Interface-Driven Peptide Folding on Simulated Membrane Surfaces DOI Creative Commons
Daniel Conde-Torres,

Mariamo Mussa-Juane,

Daniel Faílde

и другие.

Computers in Biology and Medicine, Год журнала: 2024, Номер 182, С. 109157 - 109157

Опубликована: Сен. 24, 2024

Язык: Английский

Процитировано

1
Hydrogel-antimicrobial peptide association: A novel and promising strategy to combat resistant infections DOI
Marcelo Guerrero,

David Filho,

Nicolás Ayala A

и другие.

Colloids and Surfaces B Biointerfaces, Год журнала: 2024, Номер 247, С. 114451 - 114451

Опубликована: Дек. 11, 2024

Язык: Английский

Процитировано

1
Green algae-produced multimer cathelicidin-RC1 disrupts membrane integrity for inhibiting bacterial growth DOI
Shengnan Sun, Aipo Diao, Zhen‐Chuan Fan

и другие.

Process Biochemistry, Год журнала: 2024, Номер 146, С. 1 - 12

Опубликована: Июль 3, 2024

Язык: Английский

Процитировано

0
Evaluation of the Antibacterial Potential of Two Short Linear Peptides YI12 and FK13 against Multidrug-Resistant Bacteria DOI Creative Commons
Jingyi Sun,

Pan Kong,

Jingru Shi

и другие.

Pathogens, Год журнала: 2024, Номер 13(9), С. 797 - 797

Опубликована: Сен. 14, 2024

The accelerating spread of antibiotic resistance has significantly weakened the clinical efficacy existing antibiotics, posing a severe threat to public health. There is an urgent need develop novel antimicrobial alternatives that can bypass mechanisms and effectively kill multidrug-resistant (MDR) pathogens. Antimicrobial peptides (AMPs) are one most promising candidates treat MDR pathogenic infections since they display broad-spectrum activities less prone achieve drug resistance. In this study, we investigated antibacterial capability two machine learning-driven linear peptide compounds termed YI12 FK13. We reveal FK13 exhibit properties against clinically significant bacterial pathogens, inducing no or minimal hemolysis in mammalian red blood cells. further ascertain resilient heat acid-base conditions, susceptibility hydrolytic enzymes divalent cations under physiological conditions. Initial mechanistic investigations compromise membrane integrity, leading potential dissipation excessive reactive oxygen species (ROS) generation. Collectively, our findings highlight prospective utility these cationic amphiphilic as agents.

Язык: Английский

Процитировано

0
APPLICATION OF ANTIMICROBIAL PEPTIDES IN THE POULTRY INDUSTRY DOI
Letícia Ferreira Lima, Kamila Botelho Sampaio de Oliveira,

Karen Ofuji Osiro

и другие.

Veterinary Microbiology, Год журнала: 2024, Номер 298, С. 110267 - 110267

Опубликована: Сен. 27, 2024

Язык: Английский

Процитировано

0