Recent Advances in the Development and Efficacy of Anti-Cancer Vaccines—A Narrative Review

Vaccines, Год журнала: 2025, Номер 13(3), С. 237 - 237

Опубликована: Фев. 25, 2025

Immunotherapy is an established and efficient treatment strategy for a variety of malignancies. It aims to boost the anticancer properties one’s own immune system. Several immunotherapeutic options are available, but checkpoint blockers represent most widely known investigated. Anticancer vaccines evolving area immunotherapy that stimulate antigen-presenting cells, cytotoxic responses CD8+ T presence memory among others. Over years, different approaches have been studied, such as mRNA DNA vaccines, together with dendritic cell- viral vector-based vaccines. Recently, accumulating number clinical studies performed analyze safety potential efficacy these agents. The aim this review summarize recent advances regarding types therapeutic Furthermore, it will discuss how in preclinical models can enhance outcomes.

Язык: Английский

Suppression of LIF in tumor-associated macrophages contributing to the PD-1/PD-L1 blockade in hepatocellular carcinoma

Journal of Pharmaceutical Analysis, Год журнала: 2025, Номер unknown, С. 101286 - 101286

Опубликована: Март 1, 2025

Язык: Английский