Restoring functional integrity of the global production ecosystem through biological control

Journal of Environmental Management, Год журнала: 2024, Номер 370, С. 122446 - 122446

Опубликована: Сен. 13, 2024

Язык: Английский

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A Comparative Analysis of the Antioxidant Profiles Generated by the RoXstaTM System for Diverse Biological Fluids Highlights the Powerful Protective Role of Human Seminal Plasma

Antioxidants, Год журнала: 2025, Номер 14(1), С. 90 - 90

Опубликована: Янв. 14, 2025

(1) Background: The RoXstaTM system has been developed as a rapid, effective means of profiling different types antioxidant activity. purpose this study was to examine its performance utilizing diverse array biological fluids including semen, blood plasma, serum, urine, saliva, follicular fluid and plant extracts. (2) Methods: used assess the ability suppress free radical formation well scavenge variety toxic oxygen metabolites radicals both hydrogen organic peroxides. (3) Results: Human semen shown have significantly (p < 0.001) more peroxide scavenging power than any other tested (10–14 mM vitamin C equivalent compared with 1–2 for serum or plasma), while urine particularly in preventing 0.001). powerful properties human were reside within seminal plasma (SP) fraction, rather spermatozoa, be resistant snap freezing liquid nitrogen. Moreover, comparative studies demonstrated that SP exhibited higher levels potential species examined (stallion, bull, dog) intense activity reflected relative vulnerability spermatozoa attack. (4) Conclusions: provides valuable information on profile complex fluids, supporting diagnostic role conditions associated oxidative stress. Based results secured study, is identified rich source antioxidants capable peroxides, keeping high susceptibility peroxide-mediated damage.

Язык: Английский

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Urinary glyphosate, selenium status, and their impact on mortality: Evidence from NHANES 2013–2018

Ecotoxicology and Environmental Safety, Год журнала: 2025, Номер 292, С. 117989 - 117989

Опубликована: Март 1, 2025

Glyphosate and glyphosate-based herbicides (GBHs), extensively used worldwide, have been associated with various health concerns, including an elevated risk of mortality. Experimental studies suggest that these may disrupt selenium homeostasis by hindering its uptake or promoting oxidative stress. However, the interplay between glyphosate exposure status remains poorly understood in epidemiological studies, particularly regarding selenium's role modulating mortality nationally representative populations. In this study, we analyzed data from 2013-2018 National Health Nutrition Examination Survey (NHANES), which included 6410 participants aged 3 years older. This dataset was linked to information Center for Statistics (NCHS) individuals 18 older, follow-up through 2019. The primary aim investigate relationships urinary levels, whole blood selenium, intake, influence on glyphosate-related all-cause risk. A significant negative correlation observed natural logarithm (ln) levels ln complex multiple linear regression models, a ß coefficient -0.010 (SE = 0.003, P 0.003). no association found intake. Furthermore, prominent among females, non-Hispanic whites, lower When examining relationship exposure, mortality, higher ln-urinary were significantly increased (Hazard Ratio [HR] 1.43; 95 % CI: 1.00-2.09). especially pronounced concentrations at above 50th percentile. Additionally, ln-whole protective effect against (HR 0.01; 0.00-0.18), strongest below comprehensive analysis NHANES data, our study identifies potentially harmful levels. Notably, excessively high not only reduce effects but could also increase suggesting U-shaped These findings highlight need further research into interaction status, emphasizing potential public implications.

Язык: Английский

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Re-Evaluating the Use of Glyphosate-based Herbicides: Implications on Fertility

Reproductive Sciences, Год журнала: 2025, Номер unknown

Опубликована: Март 12, 2025

Язык: Английский

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Removal of Glyphosate in Agricultural Runoff Using Subsurface Constructed Wetlands in Monocultures and Polycultures of Tropical Plants

Processes, Год журнала: 2025, Номер 13(3), С. 860 - 860

Опубликована: Март 14, 2025

Glyphosate (GLY) is the most widely used herbicide in agriculture worldwide, posing a significant contamination risk to rivers, lakes, wetlands, and soils. Its ultimate fate represents potential threat health of both terrestrial aquatic ecosystems. This study evaluated removal efficiency glyphosate conventional pollutants mesocosm-scale horizontal subsurface flow-constructed wetlands planted with Canna indica, Heliconia psittacorum, Alpinia purpurata runoff water contaminated glyphosate. Additionally, examined performances these species monoculture polyculture settings tropical ornamental plants. indica exhibited highest growth (up 160 cm) conditions, as well efficiencies for total nitrogen (TN), phosphorus (TP), phosphate (PO43⁻), achieving 91%, 93%, 98% removal, respectively. Polyculture systems demonstrated superior ammonium efficiency, reaching 94%. (>5 ppm after 40 days) psittacorum 200 were effective removal. can be effectively removed from environments through constructed species, offering sustainable approach mitigating bodies.

Язык: Английский

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The impact of acute exposure to the glyphosate-based herbicide Templo® on yellowtail tetra fish Astyanax lacustris, both before and after treatment through a vertical flow constructed wetland system

Neotropical Ichthyology, Год журнала: 2025, Номер 23(1)

Опубликована: Янв. 1, 2025

Abstract Numerous studies have investigated the genotoxicity of agricultural pesticides and potential alternatives for treatment contaminated wastewater. This particular study aimed to evaluate cyto/genotoxic effects glyphosate-based commercial herbicide Templo® on fish species Astyanax lacustris, both before after with a vertical flow constructed wetland system (VFCW). The micronucleus test (MN), cellular morphological changes (CMC), comet assay were utilized assess herbicide’s effects. A. lacustris specimens exposed concentration 20 µg/L (control group without phytoremediation = GWTP), while another underwent through (treated by TGP) duration 96 hours at same concentration. results demonstrated that induced MN formation, DNA damage, various types CMC in all tested concentrations lacustris. Notably, analyses yielded significant (p < 0.05). VFCW effectively bioremediated herbicide, achieving 95% removal rate glyphosate concentration, as confirmed liquid chromatography-mass spectrometry (UPLC-MS/MS). Therefore, presents risk cytotoxicity aquatic organisms, has proven be efficient treating this herbicide.

Язык: Английский

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Protective effects of chlorogenic acid against glyphosate-induced organ and blood toxicity in Wistar rats

Archives of Industrial Hygiene and Toxicology, Год журнала: 2025, Номер 76(1), С. 44 - 52

Опубликована: Март 1, 2025

Glyphosate, a widely used herbicide against broadleaf weeds and grasses, has been associated with various harmful effects. Our study examines the efficacy of chlorogenic acid (CGA) in alleviating toxicity glyphosate-based (GBH) 42 Wistar rats across six groups seven animals receiving either no treatment (control), CGA alone (50 mg/kg), GBH (800 or their combinations varying three doses (12.5, 25, 50 mg/kg) (CGA12.5+GBH, CGA25+GBH, CGA50+GBH, respectively) by oral gavage over 49 days row. At end experiment, samples blood, brain, heart, liver, kidney tissues were collected analysed for oxidative stress indicators (MDA, GSH, SOD, CAT), DNA damage (8-OHdG), liver function markers (AST, ALT, ALP, urea, creatinine) as well histopathological changes. As expected, increased AST creatinine, 8-OHdG, MDA levels, lowered GSH levels SOD CAT activities, leaving changes tissues. dose-dependently improved biochemical parameters reversed GBH-treated albino rats. findings consistently confirm potential promising natural agent adverse health effects exposure to glyphosate. Future research should focus on long-term glyphosate using molecular methods signalling pathways stress.

Язык: Английский

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Association of urinary glyphosate levels with iron homeostasis among a representative sample of US adults: NHANES 2013–2018

Ecotoxicology and Environmental Safety, Год журнала: 2024, Номер 284, С. 116962 - 116962

Опубликована: Авг. 28, 2024

Glyphosate and glyphosate-based herbicides (GBH), widely used globally, were initially considered harmless to humans. Experimental studies have suggested that these substances can disrupt iron homeostasis by interfering with uptake or triggering inflammatory responses. However, their potential impact on human remains underexplored.

Язык: Английский

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Chronic dietary exposure to glyphosate-induced connexin 43 autophagic degradation contributes to blood-testis barrier disruption in roosters

The Science of The Total Environment, Год журнала: 2024, Номер 951, С. 175606 - 175606

Опубликована: Авг. 17, 2024

Язык: Английский

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Correlation of Urinary Glyphosate Levels with Whole Blood Selenium Levels among a Representative Sample of US Adults: NHANES 2013-2018

Research Square (Research Square), Год журнала: 2024, Номер unknown

Опубликована: Сен. 3, 2024

Purpose: Glyphosate and glyphosate-based herbicides (GBH), extensively utilized as worldwide, have been associated with numerous health issues. Previous experimental studies indicated their potential to disrupt selenium homeostasis by either interfering uptake or increasing oxidative stress. However, there is a significant research gap concerning the connection between glyphosate exposure status in epidemiological studies, particularly within nationally representative samples. Methods: In this study, we examined data from 2013-2018 National Health Nutrition Examination Survey (NHANES), involving 3011 participants aged 3 above. Our main objective was examine urinary levels, whole blood selenium, intake. Results: Our analysis did not uncover an association Nevertheless, observed negative correlation levels ß coefficient of -1.984, S.E. = 0.639, P 0.003 final model. We also reported notable decrease average concentrations tertiles increased, P-values for trend 0.033. Furthermore, prominent among females, non-Hispanic whites, individuals lower Conclusions: thorough examination NHANES data, our study uncovers possible detrimental levels. These findings underscore importance further investigation into consequences its influence on status, thereby raising awareness implications public health.

Язык: Английский

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