Biological sex-dependent differences in postural orthostatic tachycardia syndrome DOI
Marie‐Claire Seeley, Gemma Wilson,

Eric Ong

и другие.

European Journal of Cardiovascular Nursing, Год журнала: 2025, Номер unknown

Опубликована: Март 26, 2025

Abstract Aims This prospective, cross-sectional study aimed to identify sex-based differences in diagnostic and symptom experiences postural orthostatic tachycardia syndrome (POTS). Methods results Data from participants ≥ 16 years with physician-confirmed POTS enrolled the Australian registry between 1 May 2021 30 April 2024 were analysed. Health-related quality of life was assessed using EuroQol 5 Dimension tool. Composite autonomic score (COMPASS-31) burden. Self-reported sociodemographic journey data informed experiences. In total, 452 females (mean age 31.4 ± 11.4 years) 48 males 31.1 14.6 included. Females experienced worse burden (total COMPASS-31; 50.5 13.7 vs. 42.4 16.4 for men; P < 0.001). Both sexes interacted an equivocal number doctors (P = 0.763) emergency departments 0.830) before diagnosis. had significantly longer delays than men (7.0 8.6 3.8 5.4 years; 0.010) 1.2.7 times more likely experience ≥10 delay (95% CI; 1.1–6.6). Despite latency burden, reported similar, anxiety, depression, health-related (global health rating where ‘100’ full health; females, 46.2 20.4 males, 43.7 23.6; 0.485). Conclusion significant delay. These do not seem arise variations health-seeking behaviour or reporting but rather indicate influence clinician-dependent factors. Further research is needed explore how clinician attitudes may impact sex-dependent diagnosis treatment outcomes those POTS. Registration ANZCTR:12621001034820

Язык: Английский

Biological sex-dependent differences in postural orthostatic tachycardia syndrome DOI
Marie‐Claire Seeley, Gemma Wilson,

Eric Ong

и другие.

European Journal of Cardiovascular Nursing, Год журнала: 2025, Номер unknown

Опубликована: Март 26, 2025

Abstract Aims This prospective, cross-sectional study aimed to identify sex-based differences in diagnostic and symptom experiences postural orthostatic tachycardia syndrome (POTS). Methods results Data from participants ≥ 16 years with physician-confirmed POTS enrolled the Australian registry between 1 May 2021 30 April 2024 were analysed. Health-related quality of life was assessed using EuroQol 5 Dimension tool. Composite autonomic score (COMPASS-31) burden. Self-reported sociodemographic journey data informed experiences. In total, 452 females (mean age 31.4 ± 11.4 years) 48 males 31.1 14.6 included. Females experienced worse burden (total COMPASS-31; 50.5 13.7 vs. 42.4 16.4 for men; P < 0.001). Both sexes interacted an equivocal number doctors (P = 0.763) emergency departments 0.830) before diagnosis. had significantly longer delays than men (7.0 8.6 3.8 5.4 years; 0.010) 1.2.7 times more likely experience ≥10 delay (95% CI; 1.1–6.6). Despite latency burden, reported similar, anxiety, depression, health-related (global health rating where ‘100’ full health; females, 46.2 20.4 males, 43.7 23.6; 0.485). Conclusion significant delay. These do not seem arise variations health-seeking behaviour or reporting but rather indicate influence clinician-dependent factors. Further research is needed explore how clinician attitudes may impact sex-dependent diagnosis treatment outcomes those POTS. Registration ANZCTR:12621001034820

Язык: Английский

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