Decatungstate/Cobalt Dual Catalyzed Dehydrogenation of Ketones Enabled by Polarity-Matched Site-Selective Activation

ACS Catalysis, Год журнала: 2024, Номер 14(14), С. 11138 - 11146

Опубликована: Июль 11, 2024

Язык: Английский

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Targeting Nrf2 by bioactive peptides alleviate inflammation: expanding the role of gut microbiota and metabolites

Critical Reviews in Food Science and Nutrition, Год журнала: 2024, Номер unknown, С. 1 - 20

Опубликована: Июнь 17, 2024

Inflammation is a complex process that usually refers to the general response of body harmful stimuli various pathogens, tissue damage, or exogenous pollutants. Nuclear factor erythroid 2-related 2 (Nrf2) transcription regulates cellular defense against oxidative damage and toxicity by expressing genes related stress drug detoxification. In addition its antioxidant properties, Nrf2 involved in many other important physiological processes, including inflammation metabolism. can bind promoters upregulates their expressions, which alleviate oxidation-induced inflammation. has been shown upregulate heme oxygenase-1 expression, promotes NF-κB activation closely with Nrf2, as key response, expressions pro-inflammatory factors, pathway cell Bioactive peptides come from wide range sources have biological functions. Increasing evidence indicates bioactive potential anti-inflammatory activities. This article summarized sources, absorption utilization role alleviating via pathway. also regulate gut microbiota alter metabolites, through novel supplement mechanisms peptides. review provides reference for further study on effect development functional foods.

Язык: Английский

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Scaffolds of Chitosan-metallic hybrids as antimicrobial wound dressing

Journal of Molecular Liquids, Год журнала: 2024, Номер unknown, С. 126541 - 126541

Опубликована: Ноя. 1, 2024

Язык: Английский

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Recent research on the bioactivity of polyphenols derived from edible fungi and their potential in chronic disease prevention

Journal of Functional Foods, Год журнала: 2024, Номер 124, С. 106627 - 106627

Опубликована: Дек. 12, 2024

Язык: Английский

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Microencapsulated Phytochemicals from Coriandrum sativum Enhance Ovarian Function and Modulate Gene Expression in Testosterone-Induced PCOS

Food Bioscience, Год журнала: 2025, Номер unknown, С. 105862 - 105862

Опубликована: Янв. 1, 2025

Язык: Английский

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Cianidanol from Sea Buckthorn Exert Anti-Inflammatory Effects by the Inhibiting JAK2/STAT3 Signaling Pathway via an Integrative Pharmacology Strategy

Plant Foods for Human Nutrition, Год журнала: 2025, Номер 80(1)

Опубликована: Янв. 20, 2025

Язык: Английский

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Scutellaria barbata ameliorates acute respiratory distress syndrome by inhibiting neutrophil-mediated inflammatory responses

Journal of Ethnopharmacology, Год журнала: 2025, Номер unknown, С. 119653 - 119653

Опубликована: Март 1, 2025

Язык: Английский

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Semisynthesis and biological evaluation of 17-hydroxybrevianamide N derivatives as anti-inflammatory agents by mediating NF-κB and MAPK signaling pathways

European Journal of Medicinal Chemistry, Год журнала: 2025, Номер unknown, С. 117541 - 117541

Опубликована: Март 1, 2025

Язык: Английский

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Antioxidants in cancer therapy mitigating lipid peroxidation without compromising treatment through nanotechnology

Discover Nano, Год журнала: 2025, Номер 20(1)

Опубликована: Апрель 24, 2025

Cancer treatments often exploit oxidative stress to selectively kill tumour cells by disrupting their lipid peroxidation membranes and inhibiting antioxidant enzymes. However, plays a dual role in cancer progression, acting as both promoter suppressor. Balancing through therapy remains challenge, excessive activity may compromise the efficacy of chemotherapy radiotherapy. This review explores antioxidants mitigating while maintaining treatment efficacy. It highlights recent advancements nanotechnology-based targeted delivery optimize therapeutic outcomes. A comprehensive literature was conducted using reputable databases, including PubMed, Scopus, Web Science, ScienceDirect. The search focused on publications from past five years (2020-2025), supplemented relevant studies earlier years. Keywords such "antioxidants," "lipid peroxidation," "nanotechnology therapy," "oxidative stress" were utilized. Relevant articles critically analysed, graphical illustrations created. Emerging evidence suggests that nanoparticles, liposomes, polymeric metal-organic frameworks, others, can effectively encapsulate control release minimizing systemic toxicity. Stimuli-responsive carriers with tumour-specific targeting mechanisms further enhance delivery. Studies indicate these strategies help preserve normal cells, mitigate stress-related damage, improve challenges bioavailability, stability, potential interactions standard therapies remain. Integrating nanotechnology antioxidant-based interventions presents promising approach for optimizing therapy. Future research should focus refining modulation strategies, assessing profiles during treatment, employing biomarkers determine optimal dosing. balanced use adverse effects.

Язык: Английский

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Advances of functional nanomaterials as either therapeutic agents or delivery systems in the treatment of periodontitis

Biomaterials Advances, Год журнала: 2025, Номер 175, С. 214326 - 214326

Опубликована: Апрель 27, 2025

Язык: Английский

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