Novel desfluoroquinolone-sulfonamide hybrids as potential anti-MRSA agents: synthesis, drug-likeness, molecular docking, and molecular dynamics simulation study
New Journal of Chemistry,
Год журнала:
2025,
Номер
49(6), С. 2473 - 2483
Опубликована: Янв. 1, 2025
A
molecular
hybridization
strategy
was
used
to
combine
quinolone
and
sulfonamide
structures
synthesize
16
quinolone–sulfonamide
hybrids
as
antibacterial
agents
against
methicillin-resistant
Staphylococcus
aureus
.
Язык: Английский
Identification of Ch2-Linker Modified Desfluoroquinolone-Aminopyrimidine Hybrids to Combat Antibiotic-Resistant Gram-Positive Bacteria
Опубликована: Янв. 1, 2025
Язык: Английский
Identification of CH2-linker modified desfluoroquinolone-aminopyrimidine hybrids to combat antibiotic-resistant gram-positive bacteria
Bioorganic Chemistry,
Год журнала:
2025,
Номер
161, С. 108496 - 108496
Опубликована: Апрель 21, 2025
Язык: Английский
Novel Desfluoroquinolone-Sulfonamide Hybrids as Potential Anti-Mrsa Agents: Synthesis, Drug-Likeness, Molecular Docking, and Molecular Dynamics Simulation Study
Опубликована: Янв. 1, 2024
Язык: Английский