Effects of Carotenoid Supplementation on Exercise-Induced Oxidative Stress: A Systematic Review and Meta-Analysis of Randomized Clinical Trials DOI
Xing Ye, Yanchun Li

International Journal of Sport Nutrition and Exercise Metabolism, Год журнала: 2025, Номер unknown, С. 1 - 18

Опубликована: Янв. 1, 2025

Objective : This study aims to investigate the potential effects of carotenoid supplementation on mitigating exercise-induced oxidative stress and provide guidance for future research. Methods We conducted a systematic review meta-analysis using Preferred Reporting Items Systematic Reviews Meta-Analyses guidelines. searched multiple databases from inception August 2024 randomized clinical trials investigating biomarkers stress, inflammatory markers, antioxidant levels, metabolic parameters in context stress. The search terms included “carotenoids,” “supplementation,” “exercise,” “oxidative stress,” “inflammation,” “antioxidants,” “metabolic parameters,” their synonyms. Two reviewers independently extracted data, with disagreements resolved by third reviewer. Quality was assessed Cochrane risk-of-bias method. Random fixed models were used analysis standard mean differences (SMD) or weighted (MDs) 95% confidence intervals (CI). Results A total 12 studies final analysis. Carotenoid led significant assessing induced exercise (overall stress: SMD = −0.55, CI [−1.04, −0.06]; malondialdehyde: MD −0.05, [−0.09,−0.02]; capacity: 0.03, [0.02, 0.03]; 8-isoprostane: −35.70, [−59.32, −12.09]; lipid peroxide: −1.07, [−1.94, −0.20]; nitric oxide: −8.07, [−12.54,−3.59]), markers (inflammatory levels: 1.63, [0.81, 2.46]; interleukin 1.54, [0.69, 2.40]; C-reactive protein: 4.56, [0.97, 8.14]), levels (SMD 0.84, [0.14, 1.53]), (energy expenditure: −0.52, [−0.78, −0.26]; p < .05). Conclusion appears attenuate response improve capabilities. However, these results may be influenced participant variability methodological differences. Further research larger sample sizes, longer periods, higher doses, bioavailability is needed confirm findings.

Язык: Английский

Diversity of Bioactive Compounds in Microalgae: Key Classes and Functional Applications DOI Creative Commons
Maslin Osathanunkul,

Suebsuya Thanaporn,

Lefkothea Karapetsi

и другие.

Marine Drugs, Год журнала: 2025, Номер 23(6), С. 222 - 222

Опубликована: Май 22, 2025

Microalgae offer a sustainable and versatile source of bioactive compounds. Their rapid growth, efficient CO2 utilization, adaptability make them promising alternative to traditional production methods. Key compounds, such as proteins, polyunsaturated fatty acids (PUFAs), polyphenols, phytosterols, pigments, mycosporine-like amino (MAAs), hold significant commercial value are widely utilized in food, nutraceuticals, cosmetics, pharmaceuticals, driving innovation across multiple industries. antiviral enzyme-producing capabilities further enhance industrial medical applications. Additionally, microalgae-based biostimulants plant elicitor peptides (PEPs) contribute agriculture by enhancing growth resilience environmental stressors. The GRAS status several species facilitates market integration, but challenges scaling cost reduction remain. Advances biotechnology metabolic engineering will optimize production, the global microalgae industry. With increasing consumer demand for natural, eco-friendly products, play vital role health, food security, sustainability.

Язык: Английский

Процитировано

0
Effects of Carotenoid Supplementation on Exercise-Induced Oxidative Stress: A Systematic Review and Meta-Analysis of Randomized Clinical Trials DOI
Xing Ye, Yanchun Li

International Journal of Sport Nutrition and Exercise Metabolism, Год журнала: 2025, Номер unknown, С. 1 - 18

Опубликована: Янв. 1, 2025

Objective : This study aims to investigate the potential effects of carotenoid supplementation on mitigating exercise-induced oxidative stress and provide guidance for future research. Methods We conducted a systematic review meta-analysis using Preferred Reporting Items Systematic Reviews Meta-Analyses guidelines. searched multiple databases from inception August 2024 randomized clinical trials investigating biomarkers stress, inflammatory markers, antioxidant levels, metabolic parameters in context stress. The search terms included “carotenoids,” “supplementation,” “exercise,” “oxidative stress,” “inflammation,” “antioxidants,” “metabolic parameters,” their synonyms. Two reviewers independently extracted data, with disagreements resolved by third reviewer. Quality was assessed Cochrane risk-of-bias method. Random fixed models were used analysis standard mean differences (SMD) or weighted (MDs) 95% confidence intervals (CI). Results A total 12 studies final analysis. Carotenoid led significant assessing induced exercise (overall stress: SMD = −0.55, CI [−1.04, −0.06]; malondialdehyde: MD −0.05, [−0.09,−0.02]; capacity: 0.03, [0.02, 0.03]; 8-isoprostane: −35.70, [−59.32, −12.09]; lipid peroxide: −1.07, [−1.94, −0.20]; nitric oxide: −8.07, [−12.54,−3.59]), markers (inflammatory levels: 1.63, [0.81, 2.46]; interleukin 1.54, [0.69, 2.40]; C-reactive protein: 4.56, [0.97, 8.14]), levels (SMD 0.84, [0.14, 1.53]), (energy expenditure: −0.52, [−0.78, −0.26]; p < .05). Conclusion appears attenuate response improve capabilities. However, these results may be influenced participant variability methodological differences. Further research larger sample sizes, longer periods, higher doses, bioavailability is needed confirm findings.

Язык: Английский

Процитировано

0