International Journal of Sport Nutrition and Exercise Metabolism, Год журнала: 2025, Номер unknown, С. 1 - 18
Опубликована: Янв. 1, 2025
Objective : This study aims to investigate the potential effects of carotenoid supplementation on mitigating exercise-induced oxidative stress and provide guidance for future research. Methods We conducted a systematic review meta-analysis using Preferred Reporting Items Systematic Reviews Meta-Analyses guidelines. searched multiple databases from inception August 2024 randomized clinical trials investigating biomarkers stress, inflammatory markers, antioxidant levels, metabolic parameters in context stress. The search terms included “carotenoids,” “supplementation,” “exercise,” “oxidative stress,” “inflammation,” “antioxidants,” “metabolic parameters,” their synonyms. Two reviewers independently extracted data, with disagreements resolved by third reviewer. Quality was assessed Cochrane risk-of-bias method. Random fixed models were used analysis standard mean differences (SMD) or weighted (MDs) 95% confidence intervals (CI). Results A total 12 studies final analysis. Carotenoid led significant assessing induced exercise (overall stress: SMD = −0.55, CI [−1.04, −0.06]; malondialdehyde: MD −0.05, [−0.09,−0.02]; capacity: 0.03, [0.02, 0.03]; 8-isoprostane: −35.70, [−59.32, −12.09]; lipid peroxide: −1.07, [−1.94, −0.20]; nitric oxide: −8.07, [−12.54,−3.59]), markers (inflammatory levels: 1.63, [0.81, 2.46]; interleukin 1.54, [0.69, 2.40]; C-reactive protein: 4.56, [0.97, 8.14]), levels (SMD 0.84, [0.14, 1.53]), (energy expenditure: −0.52, [−0.78, −0.26]; p < .05). Conclusion appears attenuate response improve capabilities. However, these results may be influenced participant variability methodological differences. Further research larger sample sizes, longer periods, higher doses, bioavailability is needed confirm findings.
Язык: Английский