Development of a dietary supplement with iron oxide nanoparticles and study of its chronic toxicity and biological effects DOI Creative Commons
A.S. Dydykin, E. R. Vasilevskaya, М.А. Асланова

и другие.

Food systems, Год журнала: 2025, Номер 8(1), С. 114 - 123

Опубликована: Апрель 25, 2025

Anemia is a global public health problem, the main cause of which iron deficiency in body. The difficulty enriching diet with explained by oxidative nature iron, leads to undesirable sensory changes and decrease quality shelf life food. work devoted selection bioavailable forms which, when added food an appropriate amount, are not rejected aim was study experiments on laboratory rats chronic toxicity effectiveness developed dietary supplement “PoliFerVit” comparison commercial preparations oxides E172 (Fe 2 O 3 + FeO) sulfate (FeSO 4 × 7H O). objects were (II) heptahydrate O), mixture FeO), for use as source (FeO, Fe O3, ), vitamin C, dihydroquercetin. In process work, biologically active additive (dietary supplement) developed, content 136% daily requirement. A biological activity showed that all studied objects, administered animals 32 days, did affect body weight their physiological state, also indicators general blood test, particular, leukocyte formula. revealed dynamics towards increase serum using (up 17%) 22%) indicates similar bioavailability, bioavailability higher, probably due nanoscale size particles combined composition additive. An important advantage less pronounced negative effect antioxidant system, expressed superoxide dismutase index 44%.

Язык: Английский

Development of a dietary supplement with iron oxide nanoparticles and study of its chronic toxicity and biological effects DOI Creative Commons
A.S. Dydykin, E. R. Vasilevskaya, М.А. Асланова

и другие.

Food systems, Год журнала: 2025, Номер 8(1), С. 114 - 123

Опубликована: Апрель 25, 2025

Anemia is a global public health problem, the main cause of which iron deficiency in body. The difficulty enriching diet with explained by oxidative nature iron, leads to undesirable sensory changes and decrease quality shelf life food. work devoted selection bioavailable forms which, when added food an appropriate amount, are not rejected aim was study experiments on laboratory rats chronic toxicity effectiveness developed dietary supplement “PoliFerVit” comparison commercial preparations oxides E172 (Fe 2 O 3 + FeO) sulfate (FeSO 4 × 7H O). objects were (II) heptahydrate O), mixture FeO), for use as source (FeO, Fe O3, ), vitamin C, dihydroquercetin. In process work, biologically active additive (dietary supplement) developed, content 136% daily requirement. A biological activity showed that all studied objects, administered animals 32 days, did affect body weight their physiological state, also indicators general blood test, particular, leukocyte formula. revealed dynamics towards increase serum using (up 17%) 22%) indicates similar bioavailability, bioavailability higher, probably due nanoscale size particles combined composition additive. An important advantage less pronounced negative effect antioxidant system, expressed superoxide dismutase index 44%.

Язык: Английский

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