Recent advances in wearable electrochemical sensors for in situ detection of biochemical markers

Science China Materials, Год журнала: 2025, Номер unknown

Опубликована: Фев. 14, 2025

Язык: Английский

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Novel Tapentadol Screen-Printed Carbon Sensor Integrated Copper Oxide Nanostructure

ACS Omega, Год журнала: 2025, Номер unknown

Опубликована: Янв. 15, 2025

The present study described the fabrication and electroanalytical performance of planar screen-printed disposable sensors based on copper oxide nanoparticles (CuONPs/SPEs) for voltammetric determination tapentadol (TAP) in its marketed pharmaceutical products biological fluids. CuONPs exhibited electrochemical activity against electrooxidation TAP with an anodic peak at 0.84 V BR buffer pH 5. investigations molecular orbital calculations pointed out oxidation tertiary amine group within moiety transfer two electrons protons during molecule CuONPs/SPEs surface. Linear calibration graphs were constructed covering concentration ranging from 0.83 to 738 ng mL-1 a limit detection (LOD) value up 0.24 mL-1. printed sensor offered high measurement reproducibility prolonged lifetime 6 months. Improved toward was recorded without noticeable interference degradation products, additives, excipients, uric acid, ascorbic acid. Moreover, paracetamol (PC) can be simultaneously quantified. applied monitoring residues vitro dissolution studies commercial formulations.

Язык: Английский

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Green Solid‐State Potentiometric Platform for Vonoprazan Fumarate Determination in Pharmaceutical Dosage Form and Spiked Human Plasma

Electroanalysis, Год журнала: 2025, Номер 37(2)

Опубликована: Фев. 1, 2025

Vonoprazan fumarate (VPZ), a potent potassium‐competitive acid blocker, has gained prominence recently for its efficacy in acid‐related disorders, surpassing traditional proton pump inhibitors suppression. Combining molecular modeling simulations with electrochemical sensors represents cutting‐edge approach analytical chemistry. Molecular docking guided the selection of calix[8]arene as optimal ionophore due to superior affinity VPZ, supported by robust scores and hydrophobic interactions. The final sensor configuration, incorporating calix[8]arene, sodium tetraphenylborate, dioctyl phthalate, exhibited outstanding electroanalytical characteristics, including improved slope, enhanced potential stability, rapid response times. Notably, developed solid‐contact demonstrated Nernstian slope 58.587 over concentration range 1 × 10 −8 –1 −2 M, achieving an impressive low detection limit 3.09 −9 M. method offers cost‐effective environmentally sustainable solution precise monitoring promising significant advancements pharmaceutical quality control.

Язык: Английский

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Innovative polymer-based, miniaturized solid-state reference electrode: A sustainable solution for potentiometric and electrochemical power sources

Journal of Power Sources, Год журнала: 2025, Номер 642, С. 236945 - 236945

Опубликована: Апрель 8, 2025

Язык: Английский

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β-cyclodextrin cross-linked metal organic frameworks as a new sensing candidate for donepezil hydrochloride potentiometric sensors

BMC Chemistry, Год журнала: 2025, Номер 19(1)

Опубликована: Май 29, 2025

Abstract Screen-printing is a well-established promising technology for large scale production of planner disposable electrochemical sensors. The present study aims to fabricate novel donepezil hydrochloride (DPH) screen-printed sensor integrated with the cross-linked β-cyclodextrin-functionalized aluminum metal organic framework-multiwall carbon nanotubes nanocomposites (β-CD/MOF/MWCNTs) as sensing element. fabricated sensors exhibit theoretical Nernstian compliance value 60.7 ± 1.5 mV decade −1 within linear dynamic concentration range from 10 –6 –2 mol L and limit detection 7.0 × −7 molL . DPH show high potential stability prolonged operational lifetime fast response time 6 s. presented represent an efficient analytical tool sensitive assay residues in marketed pharmaceutical tablets biological samples acceptable average recoveries under direct potentiometric measurements, flow injection analysis (FIA), titration. Moreover, dissolution degradation studies can be monitored by

Язык: Английский

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Critical assessment of different ion-to-electron transducers in modified screen-printed electrodes for potentiometric lithium sensing

Microchemical Journal, Год журнала: 2025, Номер unknown, С. 114195 - 114195

Опубликована: Июнь 1, 2025

Язык: Английский

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Acrylic molecularly imprinted polymer-based electrochemical sensor for precise nanomolar quantification of daclatasvir dihydrochloride in Daclavirdin®, Serum, and Urine

Microchemical Journal, Год журнала: 2024, Номер unknown, С. 112389 - 112389

Опубликована: Дек. 1, 2024

Язык: Английский

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