Advancing genetic improvement in the omics era: status and priorities for United States aquaculture
BMC Genomics,
Год журнала:
2025,
Номер
26(1)
Опубликована: Фев. 17, 2025
The
innovations
of
the
"Omics
Era"
have
ushered
in
significant
advancements
genetic
improvement
agriculturally
important
animal
species
through
transforming
genetics,
genomics
and
breeding
strategies.
These
were
often
coordinated,
part,
by
support
provided
over
30
years
1993-2023
National
Research
Support
Project
8
(NRSP8,
Animal
Genome
Program,
NAGRP)
affiliate
projects
focused
on
enabling
genomic
discoveries
livestock,
poultry,
aquaculture
species.
parallel
advances
demand
strategic
planning
future
research
priorities.
This
paper,
as
an
output
from
May
2023
Aquaculture
Genomics,
Genetics,
Breeding
Workshop,
provides
updated
status
resources
for
United
States
species,
highlighting
major
achievements
emerging
Finfish
shellfish
genome
omics
enhance
our
understanding
architecture
heritability
performance
production
traits.
Workshop
identified
present
aims
genomics/omics
to
build
this
progress:
(1)
advancing
reference
assembly
quality;
(2)
integrating
multi-omics
data
analysis
traits;
(3)
developing
collection
integration
phenomics
data;
(4)
creating
pathways
applying
information
across
industries;
(5)
providing
training,
extension,
outreach
application
phenome.
focuses
should
emphasize
collection,
artificial
intelligence,
identifying
causative
relationships
between
genotypes
phenotypes,
establishing
apply
tools
industries,
expansion
training
programs
next-generation
workforce
facilitate
sciences
into
operations
productivity,
competitiveness,
sustainability.
collective
vision
with
focus
highlighted
priorities
is
intended
continued
advancement
genomics,
genetics
community
industries.
Critical
challenges
ahead
include
practical
analytical
frameworks
beyond
academic
communities
that
require
collaborative
partnerships
academia,
government,
industry.
scope
review
encompasses
use
applications
study
aquatic
animals
cultivated
human
consumption
settings
throughout
their
life-cycle.
Язык: Английский
CRISPR-Based Genetic Improvement of Aquaculture Species
Fishes,
Год журнала:
2025,
Номер
10(2), С. 84 - 84
Опубликована: Фев. 18, 2025
The
clustered
regularly
interspaced
short
palindromic
repeat-associated
protein
(CRISPR-Cas)
system
is
considered
a
potential
game-changer
in
the
aquaculture
sector.
CRISPR-Cas9
derived
from
an
adaptive
mechanism
of
immune
some
prokaryotes.
CRISPR/Cas9
potentially
accelerates
rate
sustained
genetic
gain
for
and
seafood
production
sectors.
Unlike
conventional
genome-editing
techniques,
more
cost-effective,
user-friendly,
extremely
precise.
It
enables
overcoming
large-scale
challenges
aquaculture.
Traits
such
as
high
fertility,
external
fertilization,
shorter
generation
time,
well-established
breeding
methods,
ability
to
raise
larvae
offer
benefits
applying
genome
editing
most
aquacultural
species.
use
precise
where
desired
modifications
are
made
target
gene.
There
likelihood
that
intended
alterations
will
be
achieved,
resulting
transmission
trait
next
generation.
In
this
paper,
we
review
how
CRISPR
evolved,
its
basic
categories
different
Cas
systems,
well
molecular
CRISPR/Cas.
We
also
highlight
discuss
applications
CRISPR/Cas
industry.
Moreover,
using
technology
briefly
discussed.
This
pathway
charts
course
future
which
has
enable
fulfill
world
food
requirements
with
public
ecological
safety.
Язык: Английский
Genome Manipulation Advances in Selected Aquaculture Organisms
Reviews in Aquaculture,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 15, 2024
ABSTRACT
With
the
rising
global
demand
for
seafood
and
challenges
posed
by
overfishing
climate
change,
aquaculture
sector
has
become
increasingly
important
in
providing
high‐quality
protein
human
consumption.
Although
traditional
selection
breeding
programs
have
made
great
strides
genetic
improvement
of
species
over
past
decades,
faster
more
precise
tools,
such
as
genome
manipulation,
are
needed
performance
enhancement
stock.
This
review
presents
a
comprehensive
overview
current
status
three
major
manipulation
including
RNA
interference
(RNAi),
gene
transfer,
editing
species,
discusses
advances
made,
faced,
potential
future
directions
this
fast‐developing
field.
Taking
catfish
an
example,
paper
reviews
specific
applications
these
techniques
to
improve
traits
growth,
disease
resistance,
reproduction,
nutritional
profiles
various
commercially
fishes
crustaceans,
highlighting
successful
ongoing
research
efforts.
We
also
propose
CRISPR/Cas9‐mediated
multiplex
knockout
or
replacement
multiple
genes
parallel
fish.
Collectively,
provides
insights
into
evolving
landscape
sheds
light
on
its
implications
sustainable
practices
responsible
innovation.
Язык: Английский
Implementación de la tecnología CRISPR-Cas para el tratamiento de enfermedades en la acuicultura de peces. Revisión sistemática
Mighelangelo Santiago Arcila Quintero,
Sánchez Polo
Hechos Microbiológicos,
Год журнала:
2024,
Номер
15(1)
Опубликована: Янв. 1, 2024
Introducción:
Aproximadamente
el
50%
de
la
pérdida
en
producción
acuícola
destinada
al
consumo
humano
se
debe
a
enfermedades
causadas
por
patógenos.
Muchos
tratamientos
tradicionales
para
estas
están
prohibidos
debido
sus
efectos
negativos
medio
ambiente,
salud
del
consumidor
o
crecimiento
los
peces.
La
modificación
genética,
particular
mediante
tecnología
CRISPR-Cas,
ofrece
una
solución
prometedora.
Esta
permite
realizar
modificaciones
genéticas
y
detectar
secuencias
específicas
con
precisión
superior
otros
métodos.
Objetivo:
Describir
las
aplicaciones
CRISPR-Cas
tratamiento
peces
industria
acuicultura.
Metodología:
Se
realizó
búsqueda
bibliográfica
implementando
términos
aquaculture,
CRISPR,
Systems,
diseases,
fish
disease,
treatment,
treatments,
control
únicamente
artículos
originales
publicados
entre
2014
2024
inglés,
ScienceDirect,
Scopus
Google
Scholar.
Resultados:
Los
resultados
muestran
que
China
Estados
Unidos
son
líderes
este
campo.
patógenos
más
frecuentes
estudios
virales,
estudiados
Ictalurus
punctatus
Salmo
salar.
aplicación
relevante
es
diagnóstico
virales
bacterianas
fluorescencia.
está
consolidando
como
herramienta
crucial
temprano
Su
uso
expansión
abordar
tanto
dificultad
su
control.
Conclusiones:
requieren
investigaciones
confirmar
efectividad
sostenibilidad
alternativa
viable