MICRONEEDLES: REVOLUTIONIZING TRANSDERMAL DRUG DELIVERY SYSTEMS DOI Open Access

B Deepika,

A. Sajeli Begum,

Naga Raju Kandukoori

и другие.

International Journal of Applied Pharmaceutics, Год журнала: 2025, Номер unknown, С. 119 - 126

Опубликована: Май 7, 2025

Microneedles (MNDs) have emerged as a transformative technology in transdermal drug delivery, offering minimally invasive alternative to traditional hypodermic needles. These microscale devices allow the direct delivery of medication into dermal layers by creating tiny punctures skin. This article looks in-depth at various types MNDs, including hollow, hydrogel-forming, coated, dissolvable, and solid along with associated manufacturing techniques. are used many medical disciplines reduce side effects, increase patient compliance, enhance efficacy. Examples these specialties include pain treatment, hormone administration, vaccine cosmetic surgeries. Despite their promising advantages, problems education, regulatory obstacles, scalability need be fixed. describes current status MNDs technology, discusses potential changes suggests future directions for study development.

Язык: Английский

Emerging Technological Advancement for Chronic Wound Treatment and Their Role in Accelerating Wound Healing DOI
Rupita Ghosh, Prerna Singh, Ashiq Hussain Pandit

и другие.

ACS Applied Bio Materials, Год журнала: 2024, Номер 7(11), С. 7101 - 7132

Опубликована: Окт. 28, 2024

Chronic wounds are a major healthcare burden and may severely affect the social, mental, economic status of patients. Any impairment in wound healing stages due to underlying factors leads prolonged time subsequently chronic wounds. Traditional approaches for treatment include dressing free local therapy, tissue engineering based scaffold therapies. However, traditional therapies need improvisation have been advanced through breakthrough technologies. The present review spans further gives an extensive account advancements Cutting edge technologies, such as 3D printing, which includes inkjet fused deposition modeling, digital light processing, extrusion-based microneedle array-based therapies, gene microRNAs (miRNAs) smart dressings real monitoring conditions assessment pH, temperature, oxygen, moisture, metabolites, their use planning better strategies discussed detail. future direction treatments that will aid lowering caused

Язык: Английский

Процитировано

5
Nanoengineered Microneedles: A Versatile Targeted Delivery System for Theragnostic Applications DOI Creative Commons
Mansi Singh, Rahul Shukla

IntechOpen eBooks, Год журнала: 2025, Номер unknown

Опубликована: Фев. 27, 2025

Microneedles (MNs) have been used as active drug delivery carriers by precisely delivering drugs to the targeted site along with minimal tissue destruction. Earlier, MNs were for of transdermal site; now they are solid tumor site, mucosal, ophthalmic, and other organ site-specific delivery. considered a boon trans-barrier because routes, such systemic parenteral, face challenges limiting optimum amount reaching skin or barrier-containing organs. Hence, MN-mediated enhances permeation improves brain ciliary nasal clearance crossing barrier. The current book chapter mainly focuses on recent advancements in area MN-based into various parts body, their theragnostic applications, organs containing barriers, encounters has discussed. Also, comprehensive overview MN types, fabrication polymers, mechanisms release, effectiveness, advantages over conventional systems summarized.

Язык: Английский

Процитировано

0
MICRONEEDLES: REVOLUTIONIZING TRANSDERMAL DRUG DELIVERY SYSTEMS DOI Open Access

B Deepika,

A. Sajeli Begum,

Naga Raju Kandukoori

и другие.

International Journal of Applied Pharmaceutics, Год журнала: 2025, Номер unknown, С. 119 - 126

Опубликована: Май 7, 2025

Microneedles (MNDs) have emerged as a transformative technology in transdermal drug delivery, offering minimally invasive alternative to traditional hypodermic needles. These microscale devices allow the direct delivery of medication into dermal layers by creating tiny punctures skin. This article looks in-depth at various types MNDs, including hollow, hydrogel-forming, coated, dissolvable, and solid along with associated manufacturing techniques. are used many medical disciplines reduce side effects, increase patient compliance, enhance efficacy. Examples these specialties include pain treatment, hormone administration, vaccine cosmetic surgeries. Despite their promising advantages, problems education, regulatory obstacles, scalability need be fixed. describes current status MNDs technology, discusses potential changes suggests future directions for study development.

Язык: Английский

Процитировано

0