Organoids in Dynamic Culture: Microfluidics and 3D Printing Technologies DOI
Xin Su, Mingqi Wang,

Ruqiang Yuan

и другие.

ACS Biomaterials Science & Engineering, Год журнала: 2025, Номер unknown

Опубликована: Апрель 18, 2025

With the rapid advancement of biomaterials and tissue engineering technologies, organoid research its applications have made significant strides. Organoids are increasingly utilized in pharmacology, regenerative medicine, precision clinical medicine. Current trends moving toward multifunctional composite three-dimensional cultivation dynamic strategies. Key technologies driving this evolution, including 3D printing microfluidics, continue to impact new areas discovery relevance. This review provides a systematic overview these emerging trends, discussing strengths limitations critical offering insight directions for professionals working field.

Язык: Английский

ID-CRISPR: A CRISPR/Cas12a Platform for Label-Free and Sensitive Detection of Rare Mutant Alleles Using Self-Interference DNA Hydrogel Reporter DOI
Anni Deng, Zeyin Mao, Xiangyu Jin

и другие.

Biosensors and Bioelectronics, Год журнала: 2025, Номер 278, С. 117309 - 117309

Опубликована: Фев. 24, 2025

Язык: Английский

Процитировано

0
Microfluidic Innovations for Enhanced Extracellular Vesicle Isolation and Analysis: A Comprehensive Review DOI
Lin Zhu, Jingjing Du, Xiaohui Cheng

и другие.

Analytical Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Фев. 28, 2025

Язык: Английский

Процитировано

0
Automated Electroosmotic Digital Optofluidics for Rapid and Label-Free Protein Detection DOI
Yang Fan, Rongxin Fu, Yitong Liu

и другие.

Nano Letters, Год журнала: 2025, Номер unknown

Опубликована: Март 16, 2025

Rapid protein detection is crucial for medical diagnosis, clinical trials, and drug development but often faces challenges in balancing sensitivity with multiplex detection, low reagent consumption, a short time. In this work, we developed an automated sensitive electroosmotic digital optofluidics (e-DOF) platform rapid label-free biomarker quantification microliter blood samples. The hyperspectral computation reveals nanoscale morphology changes caused by target capture, eliminating multifarious enzyme-linked labeling. Electroosmosis-driven molecular circulation accelerates the immuno-hybridization, enhancing (with limit of 0.21 nM) reducing time to 15 min, compared 2–3 h traditional immunosorbent assay. hepatitis A E IgM 17 samples, results were completely consistent trial outcomes. This e-DOF system presents automated, rapid, highlighting potential applications diagnosis immunoassay research.

Язык: Английский

Процитировано

0
Organoids in Dynamic Culture: Microfluidics and 3D Printing Technologies DOI
Xin Su, Mingqi Wang,

Ruqiang Yuan

и другие.

ACS Biomaterials Science & Engineering, Год журнала: 2025, Номер unknown

Опубликована: Апрель 18, 2025

With the rapid advancement of biomaterials and tissue engineering technologies, organoid research its applications have made significant strides. Organoids are increasingly utilized in pharmacology, regenerative medicine, precision clinical medicine. Current trends moving toward multifunctional composite three-dimensional cultivation dynamic strategies. Key technologies driving this evolution, including 3D printing microfluidics, continue to impact new areas discovery relevance. This review provides a systematic overview these emerging trends, discussing strengths limitations critical offering insight directions for professionals working field.

Язык: Английский

Процитировано

0