Deleted Journal,
Год журнала:
2024,
Номер
3(2), С. 200123 - 200123
Опубликована: Март 22, 2024
With
the
rapid
development
of
additive
manufacturing
(AM),
scaffold
architectures
based
on
triply
periodic
minimal
surfaces
(TPMS)
have
attracted
increasing
interest
in
various
engineering
fields.
Nevertheless,
they
are
limited
because
complexity
design
process
when
adopted
different
research
and
In
this
work,
we
present
a
free
easy-to-use
software
package
called
TPMS_Scaffold_Generator,
which
is
coded
using
MATLAB
(Mathworks,
Inc.,
USA).
It
offers
three
function
tabs
homogeneous
tab,
heterogeneous
tab
multisymmetrical
respectively.
Variables
include
including
volume
fraction,
topology
type,
unit
cell
size,
length
architecture
X,
Y,
Z
direction,
accuracy,
style
gradient
so
forth.
TPMS_Scaffold_Generator
can
generate
TPMS
scaffolds,
especially
ultralight
scaffolds.
The
latest
version
freely
available
at:
https://github.com/LeveeLin/TPMS_Scaffold_Generator.git.
Heliyon,
Год журнала:
2024,
Номер
10(4), С. e26005 - e26005
Опубликована: Фев. 1, 2024
The
present
study
investigated
the
influence
of
pore
size
strut-based
Diamond
and
surface-based
Gyroid
structures
for
their
suitability
as
medical
implants.
Samples
were
made
additively
from
laser
powder
bed
fusion
process
with
a
relative
density
0.3
sizes
ranging
300
to
1300
μm.
They
subsequently
examined
manufacturability
mechanical
properties.
In
addition,
non-Newtonian
computational
fluid
dynamics
discrete
phase
models
conducted
assess
pressure
drop
cell
seeding
efficiency.
results
showed
that
both
had
higher
as-built
densities
smaller
sizes.
However,
demonstrated
better
its
was
closer
as-designed
one.
based
on
testing,
elastic
modulus
largely
unaffected
by
size,
but
post-yielding
behaviors
differed,
especially
in
Diamond.
High
sensitivity
could
be
explained
partly
Finite
Element
simulations,
which
revealed
stress
localization
more
uniform
distribution
Gyroid.
Furthermore,
we
defined
multiplication
product
normalized
specific
surface,
drop,
efficiency
indicator
an
optimal
this
factor
identified
approximately
500
μm
Besides,
such
criterion,
exhibited
greater
applicability
bone
scaffolds.
summary,
provides
comprehensive
assessment
effect
demonstrates
efficient
estimation
in-silico
framework
evaluating
lattice
implants,
applied
other
architectures.
Advanced Engineering Materials,
Год журнала:
2024,
Номер
26(3)
Опубликована: Янв. 11, 2024
Employing
3D
printing
bone
scaffolds
with
various
polymers
is
growing
due
to
their
biocompatibility,
biodegradability,
and
good
mechanical
properties.
However,
biological
properties
need
modification
have
fewer
difficulties
in
clinical
experiments.
Herein,
the
fused‐deposition
modeling
technique
used
design
triply‐periodic‐minimal‐surfaces
polylactic‐acid
evaluate
response
under
static
dynamic
cell
culture
conditions.
To
enhance
of
3D‐printed
scaffolds,
graphene‐oxide
(GO)
coated
on
surface
scaffolds.
Fourier‐transform
infrared
spectroscopy,
X‐ray
diffraction,
energy‐dispersion
analysis
are
conducted
check
GO
presence
its
effects.
Also,
computational
fluid
dynamics
implemented
investigate
shear
stress
scaffold,
which
a
critical
parameter
for
proliferation
Compression
tests
contact‐angle
measurements
performed
assess
effect
wettability,
respectively.
it
was
shown
that
surface‐treated
lower
higher
wettability
than
uncoated
A
perfusion
bioreactor
study
culture.
field‐emission‐scanning‐electron‐microscope
3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5
diphenyl‐tetrazolium‐bromide
(MTT)
assay
analyses
observe
viability
attachment.
An
increase
up
220%
achieved
Progress in Additive Manufacturing,
Год журнала:
2024,
Номер
unknown
Опубликована: Июль 17, 2024
Abstract
Bone
tissue
engineering
provided
the
innovative
solution
to
regenerate
bone
using
scaffolds
(porous)
structures.
This
research
investigates
optimization,
additive
manufacturing
methods
and
application
areas
of
triply
periodic
minimal
surface-based
(TPMS)
porous
structures
in
broad
field
through
literature
review.
The
properties
TPMS
are
compared
with
more
classical
strut-based
Also,
information
on
how
can
be
formulated
they
designed
obtain
desired
presented.
Attention
is
dedicated
topological
optimization
process
it
applied
further
increase
their
biomechanical
improve
design
density,
heterogenization,
unit
cell
size
grading.
Common
numerical
algorithms
as
well
difference
between
gradient-based
non-gradient-based
proposed.
Efforts
also
include
description
main
technologies
that
utilized
manufacture
either
stochastic
or
scaffolds.
present
this
work
should
able
introduce
reader
use
engineering.
Results in Engineering,
Год журнала:
2024,
Номер
21, С. 101883 - 101883
Опубликована: Фев. 12, 2024
Triply
periodic
minimal
surface
(TPMS)
structures
have
proven
to
be
suitable
for
biomorphic
scaffold
designs
orientated
towards
bone
ingrowth
applications.
In
this
work,
different
types
of
gyroid
Ti-6Al-4V
scaffolds
(skeletal-TPMS-based
and
sheet-TMPS-based)
been
designed
fabricated
by
laser
powder
bed
fusion
the
purposes
analysing
them
clarifying
which
type
could
best
option
use
in
defect
repair.
The
compression
bending
tests
conducted
demonstrated
that
skeletal
were
flexible
enough
promote
healing.
On
other
hand,
sheet
tested
might
too
rigid
optimal
growth
inside
scaffold.
torsional
properties
acceptable
most
scaffolds.
values
Darcian
permeability
all
seemed
rather
than
cartilage
ingrowth.
Biofabrication,
Год журнала:
2024,
Номер
17(1), С. 012005 - 012005
Опубликована: Ноя. 8, 2024
Abstract
Artificial
bone
graft
stands
out
for
avoiding
limited
source
of
autograft
as
well
susceptibility
to
infection
allograft,
which
makes
it
a
current
research
hotspot
in
the
field
defect
repair.
However,
traditional
design
and
manufacturing
method
cannot
fabricate
scaffold
that
mimics
complicated
bone-like
shape
with
interconnected
porous
structure
multiple
properties
akin
human
natural
bone.
Additive
manufacturing,
can
achieve
implant’s
tailored
external
contour
controllable
fabrication
internal
microporous
structure,
is
able
form
almost
any
designed
via
layer-by-layer
process.
As
additive
promising
building
artificial
scaffold,
only
combining
excellent
structural
appropriate
process
produce
ideal
biological
mechanical
properties.
In
this
article,
we
sum
up
analyze
state
art
methods
realize
shape/properties
collaborative
intelligent
manufacturing.
Scaffold
be
mainly
classified
into
based
on
unit
cells
whole
while
basic
3D
bioprinting
are
recommended
suitable
fabrication.
The
challenges
future
perspectives
manufactured
also
discussed.
Engineered Regeneration,
Год журнала:
2021,
Номер
2, С. 163 - 170
Опубликована: Янв. 1, 2021
Wearable
biosensors
are
gaining
tremendous
interest
in
the
clinical
and
biological
medical
fields
for
their
potential
providing
patients
with
real-time
diagnostic
tools
time-sensitive
information,
non-invasive
measurements
of
biochemical
markers
distributed
body
fluids
throughout
body.
These
sensors
replace
part
equipment
that
can
only
be
installed
hospitals
become
a
new
choice
assessing
human
health.
Herein,
critical
perspectives
put
forward
regarding
wearable
future
digital
health
monitoring
industry.
Moreover,
materials
processing
technologies
involved
have
also
been
discussed
recent
years,
along
schemes
system-level
integration
technologies.
Finally,
probability
being
used
early
disease
detection
is
considerable.
Thus,
despite
challenges,
it
still
quite
promising
to
come
into
production.
Engineered Regeneration,
Год журнала:
2022,
Номер
3(2), С. 163 - 181
Опубликована: Май 4, 2022
Tooth
defect
and
loss
are
common
clinical
diseases
in
stomatology.
With
the
extension
of
life
expectancy,
there
is
an
increasing
demand
for
tooth
tissue
whole
regeneration.
Compared
with
traditional
oral
prosthetic
treatment,
regeneration
has
unique
advantages
become
one
hotspots
towards
biomedical
treatment.
In
this
review,
we
discussed
development
challenges
based
on
cells
materials,
including
enamel,
dentin,
dental
pulp,
cementum,
dentin-pulp
complex,
regeneration,
order
to
provide
a
comprehensive,
up-to-date,
illustrative
overview
issues.
The
mechanisms
were
also
summarized
discussed.
Moreover,
review
hints
future
perspective
research
direction
challenging
field
regenerative
dentistry.
