Phenotypic drug discovery DOI
Sonja Sievers, Herbert Waldmann, Slava Ziegler

и другие.

Elsevier eBooks, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Язык: Английский

The Effect of Reprocessing and Moisture on Polyamide Recycling: A Focus on Neat, Composites, and Blends DOI

Johanna K. Morales,

Denis Rodrigue

Macromolecular Materials and Engineering, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 30, 2024

Abstract Polyamides (PA), commercially known as Nylon, are versatile engineering thermoplastics extensively used in different industries due to their thermal, and chemical resistance excellent mechanical properties. Although polyamide recycling has received significant attention increasing demand for sustainable practices, it is important understand the effect of factors involved this polymer. The initial part review presents an overview PA industry, its classification, properties, applications. Following this, effects reprocessing cycles examined, concluding with impact moisture before after polyamides. This not only focuses on 6 66 but also includes other grades, such 11 12. Additionally, covers blends composites.

Язык: Английский

Процитировано

4

Recent Advances in Cellulose Nanofiber Modification and Characterization and Cellulose Nanofiber-Based Films for Eco-Friendly Active Food Packaging DOI Creative Commons

Jiaojiao Sun,

Xi Yang, Yifan Bai

и другие.

Foods, Год журнала: 2024, Номер 13(24), С. 3999 - 3999

Опубликована: Дек. 11, 2024

There is growing interest in the use of bio-based materials as viable alternatives to petrochemical-based packaging. However, practical application films often hampered by their poor barrier and mechanical properties. In this context, cellulose nanofibers (CNFs) have attracted considerable attention owing exceptional biodegradability, high aspect ratio, large surface area. The extraction CNFs from agricultural waste or non-food biomass represents a sustainable approach that can effectively balance cost environmental impacts. functionalization improves economics raw production processes while expanding applications. This paper reviews recent advances nanofibers, including sources, modification, characterization techniques. Furthermore, we systematically discuss interactions with different composites development functional food films. Finally, highlight nanofiber preservation. Due environmentally friendly properties, are promising alternative petroleum-based plastics. aim present latest discoveries exploring future prospects for edible films, thereby encouraging further research field active

Язык: Английский

Процитировано

4

Research Progress in Reproductive Toxicity of Micro- and Nanoplastics on Males and Its Mechanisms DOI Creative Commons

昱 谭

Hans Journal of Food and Nutrition Science, Год журнала: 2025, Номер 14(01), С. 23 - 29

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0

Deciphering the phenotypic, inflammatory, and endocrine disrupting impacts of e-waste plastic-associated chemicals DOI Creative Commons
Andi Alijagić,

Fredric Seilitz,

Anna Bredberg

и другие.

Environmental Research, Год журнала: 2025, Номер unknown, С. 120929 - 120929

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0

Recent Advances in the Chemical Recycling of Polyamide for a Sustainable Circular Economy DOI
Yirong Feng, Xiangchun Quan, Qingya Wang

и другие.

Industrial & Engineering Chemistry Research, Год журнала: 2025, Номер unknown

Опубликована: Янв. 27, 2025

Язык: Английский

Процитировано

0

Exploring NLRP3-related phenotypic fingerprints in human macrophages using Cell Painting assay DOI Creative Commons
Matthew Herring, Eva Särndahl, Oleksandr Kotlyar

и другие.

iScience, Год журнала: 2025, Номер 28(3), С. 111961 - 111961

Опубликована: Фев. 6, 2025

Existing research has proven difficult to understand the interplay between upstream signaling events during NLRP3 inflammasome activation. Additionally, downstream of complex formation such as cytokine release and pyroptosis can exhibit variation, further complicating matters. Cell Painting emerged a prominent tool for unbiased evaluation effect perturbations on cell morphological phenotypes. Using this technique, phenotypic fingerprints be generated that reveal connections phenotypes possible modes action. To best our knowledge, was first study utilized human THP-1 macrophages generate in response different endogenous exogenous triggers identify features specific formation. Our results demonstrated not only are trigger-specific but it also cellular associated with

Язык: Английский

Процитировано

0

The impact of microplastics on antibiotic resistance genes, metal resistance genes, and bacterial community in aquaculture environment DOI

Haochang Su,

Wujie Xu, Xiaojuan Hu

и другие.

Journal of Hazardous Materials, Год журнала: 2025, Номер 489, С. 137704 - 137704

Опубликована: Фев. 20, 2025

Язык: Английский

Процитировано

0

Microplastic contamination in threatened wild felids of India: Understanding environmental uptake, feeding implications, and associated risks DOI

Shrayan Bhattacharjee,

Pradipta Kumar Ghosh,

Shambadeb Basu

и другие.

Environmental Research, Год журнала: 2025, Номер unknown, С. 121218 - 121218

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

0

Biological Effects of Micro-/Nano-Plastics in Macrophages DOI Creative Commons
Massimiliano G. Bianchi, Lavinia Casati,

Giulia Sauro

и другие.

Nanomaterials, Год журнала: 2025, Номер 15(5), С. 394 - 394

Опубликована: Март 4, 2025

The environmental impact of plastics is worsened by their inadequate end-of-life disposal, leading to the ubiquitous presence micro- (MPs) and nanosized (NPs) plastic particles. MPs NPs are thus widely present in water air inevitably enter food chain, with inhalation ingestion as main exposure routes for humans. Many recent studies have demonstrated that gain access several body compartments, where they taken up cells, increase production reactive oxygen species, lead inflammatory changes. In most tissues, resident macrophages engage first approach foreign materials, this interaction largely affects subsequent fate material possible pathological outcomes. On other hand, organizers controllers both responses tissue repair. Here, we aim summarize available information on NPs. Particular attention will be devoted consequences macrophage viability functions, well implications pathology.

Язык: Английский

Процитировано

0

In vitro cell-transforming capacity of micro- and nanoplastics derived from 3D-printing waste DOI Creative Commons

Adriana Rodríguez-Garraus,

Mari Venäläinen,

Jussi Lyyränen

и другие.

Ecotoxicology and Environmental Safety, Год журнала: 2025, Номер 293, С. 118007 - 118007

Опубликована: Март 1, 2025

The increasing use of plastic polymers in 3D printing applications may lead to human exposure micro- and nanoplastics (MNPLs), raising concerns regarding adverse health consequences such as cancer induction. Little attention has been given MNPLs originated at the end life cycle 3D-printed objects because mechanical environmental degradation waste. This study assessed carcinogenic potential secondary generated through cryomilling using validated vitro Bhas 42 cell transformation assay (CTA). Three-dimensional were printed four types polycarbonate (PC)- polypropylene (PP)-modified thermoplastic filaments, undoped doped with single-walled carbon nanotubes (PC-CNT) silver nanoparticles (PP-Ag), respectively. (< 5 µm) following a three-step top-down process thoroughly characterized. cells treated once (initiation assay) or repeatedly (promotion several concentrations (3.125-100 µg/mL) mimicking realistic conditions, transformed foci formation was evaluated after 21 days. Furthermore, cellular internalization mRNA expression seven genes previously recognized part predictive early signature also evaluated. Despite being internalized, none particles able initiate promote transformation, regardless doping nanomaterials. Alternatively, all significantly increased decreased Prl2c3 Timp4, respectively, under promotion indicating changes that occur before foci. These findings suggest test could have tumorigenic despite not showing morphological cells.

Язык: Английский

Процитировано

0