Prevalence of synthetic phenolic antioxidants in food contact materials from China and their implications for human dietary exposure through take-away food

Journal of Hazardous Materials, Год журнала: 2024, Номер 473, С. 134599 - 134599

Опубликована: Май 13, 2024

Язык: Английский

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The benefits of removing toxic chemicals from plastics

Proceedings of the National Academy of Sciences, Год журнала: 2024, Номер 121(52)

Опубликована: Дек. 16, 2024

More than 16,000 chemicals are incorporated into plastics to impart properties such as color, flexibility, and durability. These may leach from plastics, resulting in widespread human exposure during everyday use. Two plastic-associated chemicals—bisphenol A (BPA) di(2-ethylhexyl) phthalate (DEHP)—and a class of chemicals—brominated flame retardants [polybrominated diphenyl ethers (PBDEs)]—are credibly linked adverse health cognitive impacts. BPA exposures associated with ischemic heart disease (IHD) stroke, DEHP increased all-cause mortality among persons 55 64 y old, prenatal PBDE mothers IQ losses their children. We estimate BPA, DEHP, 38 countries containing one-third the world’s population. find that 2015, 5.4 million cases IHD 346,000 stroke were exposure; approximately 164,000 deaths 55-to-64 olds; 11.7 points lost due maternal exposure. costs these impacts be $1.5 trillion 2015 purchasing power parity dollars. If United States had been at levels since 2003, 515,000 fewer would have attributed between 2003 2015. 2005, over 42 saved 2005

Язык: Английский

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Metabolic and molecular Characterization, following dietary exposure to DINCH, Reveals new Implications for its role as a Metabolism-Disrupting chemical

Environment International, Год журнала: 2025, Номер unknown, С. 109306 - 109306

Опубликована: Янв. 1, 2025

Язык: Английский

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Chemical Migration of Polycyclic Aromatic Hydrocarbons and Other Compounds from Plastic Food Packaging: Assessment of Food Safety Risks and Health Impacts

Foods, Год журнала: 2025, Номер 14(6), С. 1013 - 1013

Опубликована: Март 17, 2025

The potential migration of chemical compounds from plastic food packaging poses significant health risks, necessitating continuous monitoring and enhanced safety protocols. This study aimed to investigate the nine groups, including alanine, acetic acid, cyano derivatives, urea, amines, amides, benzene nitrites, non-specified compounds, across different categories. A total 195 packaged samples eleven categories were analyzed using Headspace Gas Chromatography-Mass Spectrometry (GC-MS) identify quantify migrants. Statistical analysis revealed differences in levels among (p < 0.05). Cheese, candies, chips exhibited highest concentrations alanine (65.95 ± 0.6384 mg/kg), acid (57.80 0.6383 derivatives (59.96 1.844 respectively, while frozen raw meat seafood showed lowest for most compounds. High nitrite certain raised particular concern due their carcinogenic toxicological effects. Regression confirmed that matrix type is a strong predictor several findings emphasize urgent need stricter regulation, improved analytical techniques, development safer materials reduce risks protect public health.

Язык: Английский

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In Vitro Hazard Characterization of Contaminants Migrating from Recycled Paper Food Contact Materials

Regulatory Toxicology and Pharmacology, Год журнала: 2025, Номер unknown, С. 105816 - 105816

Опубликована: Март 1, 2025

Язык: Английский

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Plastic chemicals disrupt molecular circadian rhythms via adenosine 1 receptor in vitro

Environment International, Год журнала: 2025, Номер unknown, С. 109422 - 109422

Опубликована: Март 1, 2025

The adenosine 1 receptor (A1R) is a G protein-coupled that transduces signals to regulate sleep-wake cycles and circadian rhythms. Plastic products contain thousands of chemicals, known disrupt physiological function. Recent research has demonstrated some these chemicals are also A1R agonists, however, the extent which such activation propagates downstream results in cellular alterations remains unknown. Thus, we investigate whether extracted from polyurethane (PUR) polyvinyl chloride (PVC) plastics rhythms via agonism A1R. We confirm plastic both activate inhibit intracellular cAMP U2OS cells. Notably, this inhibition comparable induced by highly specific agonist 2'-MeCCPA. To assess disruption, quantify temporal expression patterns clock genes PER2 CRY2 at 4-h intervals over 48 h. Here, exposure shifts phase oscillatory 9-17 min. Importantly, effects dose-dependent reversible when inhibited pharmacological antagonist. This demonstrates can processes interfering with signaling suggests novel mechanism other may contribute non-communicable diseases.

Язык: Английский

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Environmental and littering impacts of disposable cups made of polypropylene and polylactic acid in Germany

Sustainable Production and Consumption, Год журнала: 2025, Номер unknown

Опубликована: Апрель 1, 2025

Язык: Английский

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Migration of chemical substances from packaging materials to food

Food Chemistry, Год журнала: 2025, Номер 485, С. 144544 - 144544

Опубликована: Апрель 26, 2025

Язык: Английский

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Diabetes from plastics: role of endocrine disruptors in β-cell physiology

Annales d Endocrinologie, Год журнала: 2025, Номер 86(3), С. 101780 - 101780

Опубликована: Май 6, 2025

Язык: Английский

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Health impacts of exposure to synthetic chemicals in food

Nature Medicine, Год журнала: 2025, Номер 31(5), С. 1431 - 1443

Опубликована: Май 1, 2025

Язык: Английский

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