THE EFFECT OF NANOPLASTICS AND MICROPLASTICS ON LUNG MORPHOLOGY AND PHYSIOLOGY: A SYSTEMATIC REVIEW DOI Creative Commons

Y.V. Rybalchenko

The Medical and Ecological Problems, Год журнала: 2024, Номер 28(3), С. 42 - 60

Опубликована: Дек. 30, 2024

Airborne microplastic (NP) and nanoplastic (MP) pollution has emerged as a pressing environmental concern with significant implications for human health. While MPs are present both indoors outdoors, indoor concentrations generally higher due to the abrasion of household materials, furniture, other domestic sources. NPs, when inhaled, accumulate in various lung regions, exerting toxic effects potentially leading respiratory diseases. This systematic review, conducted according PRISMA guidelines, evaluates recent experimental studies on pathogenic impact nanomicroplastics (NMPs) tissues using vivo vitro models. The review included 10 analyzing MP accumulation 90 examining pathogenetic mechanisms exposure. Research data indicates predominance polymeric fibers such polypropylene, polyethylene terephthalate, polytetrafluoroethylene, accounting nearly half structures. NMPs exhibit size- composition-dependent accumulation, smaller positively charged particles showing translocation potential systemic circulation organs. highlights synergistic heavy metals pollutants, interaction pulmonary surfactant, role exacerbating Current analysis underscores growing interest NMP-related health risks identifies knowledge gaps, including need standardization NMP toxicity testing further exploration biological systems. findings emphasize importance mitigating exposure safeguard pave way future research long-term impacts airborne

Язык: Английский

The histopathological and functional consequences of microplastic exposure DOI Creative Commons

Yujeong Lee,

Min Kyung Sung, Soo‐Eun Sung

и другие.

Deleted Journal, Год журнала: 2025, Номер 7(1)

Опубликована: Янв. 11, 2025

As the production, usage, and disposal of plastics increase, microplastics generated—plastic particles smaller than 5 mm—increases, exacerbating environmental pollution. In turn, various organisms become increasingly exposed to contaminated environments, potentially affecting humans through food chain. Crucial findings from in vivo experiments indicate histopathological changes caused by impact morphology physiological function organisms. This study describes induced across circulatory, nervous, digestive, respiratory, reproductive systems explains associated functional alterations. Except nervous system, main morphological involve degenerative throughout body, such as apoptosis, inflammation, fibrosis. Most were inflammatory responses microplastics, leading fibrosis subsequent impairments. Various studies confirm that stimulate cells, increased reactive oxygen species cell death. Consequently, these impair related systemic functions. review highlights fundamental organs cells due discusses limitations involving showing no changes.

Язык: Английский

Процитировано

2

A review on advancements in atmospheric microplastics research: The pivotal role of machine learning DOI

Jiaer Yang,

Zezhi Peng,

Jian Sun

и другие.

The Science of The Total Environment, Год журнала: 2024, Номер 945, С. 173966 - 173966

Опубликована: Июнь 17, 2024

Язык: Английский

Процитировано

9

Ecological and Health Risk Mediated by Micro(nano)plastics Aging Process: Perspectives and Challenges DOI
Kyuseok Song, Shu-Hong Gao,

Yu-Sheng Pan

и другие.

Environmental Science & Technology, Год журнала: 2025, Номер unknown

Опубликована: Март 19, 2025

Aged micro(nano)plastics (MNPs) are normally the ultimate state of plastics in environment after aging. The changes physical and chemical characteristics aged MNPs significantly influence their environmental behavior by releasing additives, forming byproducts, adsorbing contaminants. However, a systematic review is lacking on effects ecological human health regarding increasing but scattered studies results. This Review first summarizes unique methods for quantifying aging degree. Then we focused potential impacts organisms, ecosystems, health, including "Trojan horse" under real conditions. Through combining meta-analysis analytic hierarchy process (AHP) model, demonstrated that, compared to virgin MNPs, would result biomass decrease oxidative stress increase organisms lead total N/P greenhouse gas emissions ecosystems while causing cell apoptosis, antioxidant system reaction, inflammation health. Within framework risk assessment, used quotient (RQ) physiologically based pharmacokinetic (PBK) models as examples illustrate importance considering degree data acquisition, model building, formula evaluation. Given risks our urgent call more understand hazards real-world environments.

Язык: Английский

Процитировано

1

Aggregation kinetics of diesel soot nanoparticles in lung fluids: Effects of exposure conditions, fluid properties, and pulmonary surfactant lipids DOI
Jiawei Dong, Shijie Luo,

Xiaolin Huang

и другие.

Journal of Hazardous Materials, Год журнала: 2025, Номер unknown, С. 138079 - 138079

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0

The Hidden Health Crisis: Microplastics and Their Medical Consequences DOI Creative Commons
Jakub Roman, Daniel Gondko,

Patrycja Dębiec

и другие.

Journal of Education Health and Sport, Год журнала: 2024, Номер 72, С. 51690 - 51690

Опубликована: Май 31, 2024

Introduction and Purpose: Microplastics, ubiquitous environmental contaminants, are increasingly recognized for their potential to impact human health. This review aims consolidate existing knowledge on the pathways through which microplastics interact with biological systems elucidate health implications. State of Knowledge: Microplastics pervasive in various environments, from aquatic terrestrial ecosystems, they eventually enter body via ingestion, inhalation, or dermal absorption. Studies have suggested that carry toxic substances, such as heavy metals organic pollutants, known endocrine disruptors carcinogens. Additionally, physical presence has been linked inflammation other negative outcomes. Research this field is complex interdisciplinary, involving toxicology, science, public disciplines. Summary: The concerning, there a clear need further research understand extent risks associated chronic exposure. Public strategies should include both reducing microplastic pollution strengthening regulations plastic waste. Meanwhile, medical professionals consider exposure when diagnosing treating conditions. Future aim clarify mechanisms toxicity establish safe levels exposure, multidisciplinary approach being essential comprehensive understanding effective intervention.

Язык: Английский

Процитировано

3

Exposure to O3 and NO2 on the interfacial chemistry of the pulmonary surfactant and the mechanism of lung oxidative damage DOI
Jie Li, Haoran Song, Tao Luo

и другие.

Chemosphere, Год журнала: 2024, Номер 362, С. 142669 - 142669

Опубликована: Июнь 19, 2024

Язык: Английский

Процитировано

2

Interaction of diesel exhaust particulate matter with mucins in simulated saliva fluids: Bioaccessibility of heavy metals and potential health risks DOI
Jiao Li,

Haorang Song,

Linfeng Zhang

и другие.

Journal of Hazardous Materials, Год журнала: 2024, Номер 480, С. 135811 - 135811

Опубликована: Сен. 10, 2024

Язык: Английский

Процитировано

2

Airborne micro- and nanoplastics: emerging causes of respiratory diseases DOI Creative Commons
Zixuan Gou, Haonan Wu, Shanyu Li

и другие.

Particle and Fibre Toxicology, Год журнала: 2024, Номер 21(1)

Опубликована: Дек. 4, 2024

Airborne micro- and nanoplastics (AMNPs) are ubiquitously present in human living environments pose significant threats to respiratory health. Currently, much research has been conducted on the relationship between (MNPs) cardiovascular gastrointestinal diseases, yet there is a clear lack of understanding regarding link AMNPs diseases. Therefore, it imperative explore two. Recent extensive studies by numerous scholars characteristics their with diseases have robustly demonstrated that from various sources significantly influence onset progression conditions. Thus, investigating intrinsic mechanisms involved finding necessary preventive therapeutic measures crucial. In this review, we primarily describe fundamental AMNPs, impact system, toxic facilitate disease development. It hoped article will provide new insights for further contribute advancement

Язык: Английский

Процитировано

2

Potential Impact Microplastic Polyethylene Terephthalate on Mice DOI Open Access
Marchel Putra Garfansa, Roy Hendroko Setyobudi, Iswahyudi Iswahyudi

и другие.

Sarhad Journal of Agriculture, Год журнала: 2024, Номер 39(s1)

Опубликована: Янв. 1, 2024

Microplastic (MPs) pollution is an increasing global problem, creating deep concerns regarding its potential impact on human health.Numerous experiments have been conducted living organisms to investigate the dispersion patterns of MPs.Furthermore, extent distribution and research MPs about mice still needs be improved.This study aimed determine PET (polyethylene terephthalate) mice's weight, feces, appetite.Four feed experiments, P0 (pellet BR1), P1 (potato from Pujon Farm), P2 mixed 300 µg PET), P3 600 were investigated in this research.PET at a dose had worst compared others.There changes eating performance, body feces treatment due contained them.Another consequence anticipated: A reduction microbial diversity intestines mice, resulting fall both weight mice.

Язык: Английский

Процитировано

1

Decoding green food safety information dependency in the digital era: An intelligent validation using SEM-ANN framework DOI
Tong Zhao, Qiumei Shi, X.S. Zhang

и другие.

Journal of Retailing and Consumer Services, Год журнала: 2024, Номер 79, С. 103886 - 103886

Опубликована: Май 6, 2024

Язык: Английский

Процитировано

0