Electrochemical Technology for the Detection of Tau Proteins as a Biomarker of Alzheimer’s Disease in Blood

Biosensors, Год журнала: 2025, Номер 15(2), С. 85 - 85

Опубликована: Фев. 4, 2025

Alzheimer’s disease (AD) is a prevalent neurodegenerative disorder and significant cause of dementia in elderly individuals, with growing prevalence our aging population. Extracellular amyloid-β peptides (Aβ), intracellular tau proteins, their phosphorylated forms have gained prominence as critical biomarkers for early precise diagnosis AD, correlating progression response to therapy. The high costs invasiveness conventional diagnostic methods, such positron emission tomography (PET) magnetic resonance imaging (MRI), limit suitability large-scale or routine screening. However, electrochemical (EC) analysis methods made progress detection due sensitivity, excellent specificity, portability, cost-effectiveness. This article reviews the EC biosensing technologies, focusing on protein blood (a low-invasive, accessible medium). then discusses various sensing platforms, including fabrication processes, (LOD), clinical potential show role these sensors transformers changing face AD diagnostics.

Язык: Английский

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Automated synthesis and processing of functional nanomaterials: Advances and perspectives

Coordination Chemistry Reviews, Год журнала: 2024, Номер 523, С. 216249 - 216249

Опубликована: Окт. 11, 2024

Язык: Английский

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Phosphorothioated oligonucleotides on gold-coated electrospun polymeric fibers for electrochemical genosensors

Electrochimica Acta, Год журнала: 2025, Номер unknown, С. 146006 - 146006

Опубликована: Март 1, 2025

Язык: Английский

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Review of Recent Advances in Aptasensor for the Detection of Pathogenic Escherichia coli O157: H7

Journal of Food Safety, Год журнала: 2025, Номер 45(3)

Опубликована: Апрель 30, 2025

ABSTRACT Escherichia coli ( E. ) O157: H7 is a critical pathogen due to its association with severe conditions like hemorrhagic colitis and hemolytic uremic syndrome. The prevalence of this underscores the urgent need for effective food environmental safety measures. Among emerging innovations, aptamer‐based biosensors (aptasensors) offer increased sensitivity reduced detection times compared traditional methods identifying H7. Aptamers, short single‐stranded DNA (ssDNA) or RNA molecules, act as bio‐recognition elements, exhibiting high specificity affinity foodborne pathogens. This scoping review examines recent advancements in aptasensor technology over past 5 years, focusing on platforms targeting detection. Key elements such targets, sample types, transducers, sensing mechanisms, fabrication methods, limits were analyzed identify strengths limitations current platforms. findings indicate that most optical aptasensors, particularly fluorescence‐based ones, have been developed detecting water, food, milk samples. Currently developing aptasensors show promise, offering reliable alternatives improved capabilities. Nonetheless, further studies are still needed validate their facilitate broader applications. explores latest developments across diverse including electrochemical, optical, magnetic approaches, working principles, advantages, limitations. It highlights potential practical applications agricultural samples, emphasizing role advancing monitoring systems.

Язык: Английский

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Engineering Signal Interfaces for Enhanced Electrochemical Biosensing

TrAC Trends in Analytical Chemistry, Год журнала: 2025, Номер unknown, С. 118310 - 118310

Опубликована: Май 1, 2025

Язык: Английский

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Biosensors based on DNA aptamers for detection of bacterial pathogens in food

Advances in food and nutrition research, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Язык: Английский

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Rapid visual detection of tobacco mosaic virus using a portable paper-based molecularly imprinted sensor

Sensors and Actuators B Chemical, Год журнала: 2024, Номер 424, С. 136909 - 136909

Опубликована: Ноя. 7, 2024

Язык: Английский

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