Unravelling the Antimicrobial, Antibiofilm, Suppressing Fibronectin Binding Protein A (fnba) and cna Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized Solanum lycopersicum Silver Nanoparticles

Medicina, Год журнала: 2024, Номер 60(3), С. 515 - 515

Опубликована: Март 21, 2024

Background and Objectives: Urinary tract infections [UTIs] are considered the third most known risk of infection in human health around world. There is increasing appreciation for pathogenicity Gram-positive Gram-negative strains UTIs, aside from fungal infection, as they have numerous virulence factors. Materials Methods: In this study, fifty urine samples were collected patients suffering UTI. Among isolates UTI microbes, six described MDR after an antibiotic susceptibility test carried out using ten different antibiotics. An alternative treatment microbial elimination involved use biosynthesized silver nanoparticles (AgNPs) derived Solanum lycopersicum [S. cumin]. Results: The sizes shapes AgNPs characterized through TEM imaging, which showed spherical particles a size range 35–80 nm, average was 53 nm. Additionally, demonstrated inhibitory activity against Staphylococcus aureus (OR648079), exhibiting 31 mm zone inhibition at minimum concentration (MIC) 4 mg/mL bactericidal (MBC) 8 mg/mL. This followed by Aspergillus niger (OR648075), 30 MIC 16 fungicidal (MFC) 32 Then, Enterococcus faecalis (OR648078), Klebsiella pneumoniae (OR648081), Acinetobacter baumannii (OR648080) each displayed 29 MBC least observed Candida auris (OR648076), with 25 MFC Furthermore, concentrations removed DPPH H2O2 IC50 value 13.54 μg/mL. Also, 3 remarkable DNA fragmentation all bacterial except faecalis. phytochemical analysis presence active organic components plant extract, concluded that rutin 88.3 mg/g, garlic acid 70.4 tannic 23.7 mg/g. Finally, 3–6 decreased expression two fundamental genes necessary biofilm formation within aureus, fnbA (6 folds), Cna (12.5 folds) when compared RecA gene, one-fold control sample. These submitted NCBI accession numbers [OR682119] [OR682118], respectively. Conclusions: findings study indicate exhibit promising antimicrobial antioxidant properties pathogens, including resistant to multiple suggests their potential effective UTIs. Further research warranted fully understand mechanisms action explore therapeutic applications these combating

Язык: Английский

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Wild edible mushrooms to achieve sustainable development goals: Novel sources for food security, health, and well-being

Food Bioscience, Год журнала: 2024, Номер 60, С. 104277 - 104277

Опубликована: Май 7, 2024

Язык: Английский

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Valorization of Mushroom Spent Mushroom Substrate: A Sustainable Approach to Remediation of Xenobiotic Compounds- A Comprehensive Review

Groundwater for Sustainable Development, Год журнала: 2024, Номер 26, С. 101290 - 101290

Опубликована: Июль 18, 2024

Язык: Английский

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Rationally designed molecular logic gates using sensing parameters of plasmon based core@shell nanostructure

Journal of Industrial and Engineering Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Март 1, 2025

Язык: Английский

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Red-Emitting LiAlSiO4:Eu3+ Nanophosphors: A Versatile Material for Lighting, Forensic and Anti-Counterfeiting Technologies

Journal of Luminescence, Год журнала: 2025, Номер unknown, С. 121240 - 121240

Опубликована: Апрель 1, 2025

Язык: Английский

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Characterization and Antibacterial Activity of Silver Nanoparticles Synthesized from Oxya chinensis sinuosa (Grasshopper) Extract

Microorganisms, Год журнала: 2024, Номер 12(10), С. 2089 - 2089

Опубликована: Окт. 18, 2024

In this study, silver nanoparticles (AgNPs) were synthesized using a green method from an extract of the edible insect Oxya chinensis sinuosa (O_extract). The formation AgNPs (O_AgNPs) was confirmed via UV–vis spectroscopy, and their stability assessed Turbiscan analysis. size morphology particles characterized transmission electron microscopy field-emission scanning microscopy. Dynamic light scattering zeta potential analyses further distribution dispersion particles. average particle 111.8 ± 1.5 nm, indicating relatively high stability. O_AgNPs X-ray photoelectron spectroscopy (XPS), high-resolution diffraction (HR-XRD), Fourier transform infrared (FTIR) spectroscopy. XPS analysis chemical composition O_AgNP surface, whereas HR-XRD its crystallinity. FTIR suggested that O_extract plays crucial role in synthesis process. antibacterial activity demonstrated disk diffusion assay, which revealed effective against common foodborne pathogens, including Salmonella Typhimurium, Escherichia coli, Staphylococcus aureus, Bacillus cereus. exhibited clear activity, with inhibition zones 15.08 0.45 mm for S. 15.03 0.15 E. 15.24 0.66 13.30 0.16 B. These findings suggest have use as agents bacteria.

Язык: Английский

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Sensitive Detection of Bisphenol a Based on Resonance Energy Transfer between Zinc Oxide Nanoparticles Enhanced Luminol Ecl and Silver Nanoparticles Decorated Tivc Mxene

Опубликована: Янв. 1, 2024

Язык: Английский

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Sensitive detection of bisphenol A based on resonance energy transfer between zinc oxide nanoparticles enhanced luminol ECL and silver nanoparticles decorated TiVC MXene

Microchemical Journal, Год журнала: 2024, Номер unknown, С. 111968 - 111968

Опубликована: Окт. 1, 2024

Язык: Английский

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