IEEE Access,
Год журнала:
2023,
Номер
12, С. 1434 - 1457
Опубликована: Дек. 15, 2023
Cancer
is
a
leading
global
cause
of
death.
Histopathology
image
analysis
widely
recognized
as
the
gold
standard
for
cancer
diagnosis,
playing
crucial
role
in
early
detection
and
reducing
mortality
rates.
However,
this
diagnostic
task
performed
manually
by
pathologists,
to
high
human
errors
variabilities
due
huge
number
images
screen
tissue
complexities.
With
emergence
deep
learning,
specifically
Convolutional
Neural
Network
(CNN),
computer-aided
there
growing
interest
from
medical
community
automate
labor-intensive
manual
screening.
Despite
its
promising
performance,
learning
models
still
encounter
challenges
when
it
comes
extracting
comprehensive
histopathological
features
optimal
results.
To
tackle
issue,
our
study
introduces
based
on
intra-domain
transfer
ensemble
learning.
We
evaluated
these
public
histopathology
datasets,
including
Gastric
Sub-size
Image
Database
(GasHisSDB),
Chaoyang
colorectal,
Clinical
Proteomic
Tumor
Analysis
Consortium
Clear
Cell
Renal
Carcinoma
(CPTAC-CCRCC).
Our
achieved
state-of-the-art
accuracy:
99.78%
GasHisSDB,
85.69%
Chaoyang,
99.17%
CPTAC-CCRCC.
These
results
highlight
models'
ability
extract
rich
perform
well
low-resolution
images.
Thus,
have
potential
assist
reduce
their
workload,
enhance
patient
survival
IEEE Journal of Biomedical and Health Informatics,
Год журнала:
2024,
Номер
28(6), С. 3557 - 3570
Опубликована: Март 8, 2024
Grading
laryngeal
squamous
cell
carcinoma
(LSCC)
based
on
histopathological
images
is
a
clinically
significant
yet
challenging
task.
However,
more
low-effect
background
semantic
information
appeared
in
the
feature
maps,
channels,
and
class
activation
which
caused
serious
impact
accuracy
interpretability
of
LSCC
grading.
While
traditional
transformer
block
makes
extensive
use
parameter
attention,
model
overlearns
information,
resulting
ineffectively
reducing
proportion
semantics.
Therefore,
we
propose
an
end-to-end
network
with
transformers
constrained
by
learned-parameter-free
attention
(LA-ViT),
improve
ability
to
learn
high-effect
target
reduce
Firstly,
according
generalized
linear
probabilistic,
demonstrate
that
(LA)
has
stronger
highly
effective
than
attention.
Secondly,
first-type
LA
LA-ViT
utilizes
map
position
subspace
realize
query.
Then,
it
uses
channel
key,
adopts
average
convergence
obtain
value.
And
those
construct
mechanism.
Thus,
reduces
semantics
maps
channels.
Thirdly,
second-type
probability
matrix
decision
level
weight
key
query,
respectively.
So,
maps.
Finally,
build
new
complex
pathology
image
dataset
address
problem,
less
research
grading
models
because
lacking
meaningful
datasets.
After
experiments,
whole
metrics
outperform
other
state-of-the-art
methods,
visualization
match
better
regions
interest
pathologists'
decision-making.
Moreover,
experimental
results
conducted
public
show
superior
generalization
performance
methods.
BioMedical Engineering OnLine,
Год журнала:
2023,
Номер
22(1)
Опубликована: Сен. 25, 2023
Transformers
have
been
widely
used
in
many
computer
vision
challenges
and
shown
the
capability
of
producing
better
results
than
convolutional
neural
networks
(CNNs).
Taking
advantage
capturing
long-range
contextual
information
learning
more
complex
relations
image
data,
applied
to
histopathological
processing
tasks.
In
this
survey,
we
make
an
effort
present
a
thorough
analysis
uses
analysis,
covering
several
topics,
from
newly
built
Transformer
models
unresolved
challenges.
To
be
precise,
first
begin
by
outlining
fundamental
principles
attention
mechanism
included
other
key
frameworks.
Second,
analyze
Transformer-based
applications
imaging
domain
provide
evaluation
100
research
publications
across
different
downstream
tasks
cover
most
recent
innovations,
including
survival
prediction,
segmentation,
classification,
detection,
representation.
Within
survey
work,
also
compare
performance
CNN-based
techniques
based
on
recently
published
papers,
highlight
major
challenges,
interesting
future
directions.
Despite
outstanding
architectures
number
papers
reviewed
anticipate
that
further
improvements
exploration
are
still
required
future.
We
hope
paper
will
give
readers
field
study
understanding
up-to-date
list
summary
provided
at
https://github.com/S-domain/Survey-Paper
.
IEEE Journal of Biomedical and Health Informatics,
Год журнала:
2024,
Номер
28(4), С. 2091 - 2102
Опубликована: Янв. 9, 2024
Digital
pathology
images'
extensive
cellular
information
provide
a
trustworthy
foundation
for
tumor
diagnosis.
With
the
aid
of
computer-aided
diagnostics,
pathologists
can
locate
crucial
more
quickly.
The
cascade
structure
refines
segmentation
results
by
utilizing
its
multi-task
and
multi-stage
characteristics.
However,
cascade-based
models
require
downsampling
cropping
patches
during
inference
process
due
to
ultra-high
resolution
complex
images.
This
not
only
increases
cost
computation
time
but
also
in
loss
details
corrupts
global
contextual
information.
study
proposes
Pathology
Image
Assistance
Program
(CRSDPI)
medical
decision-making
systems
that
is
based
on
continuous
improvement.
After
locating
region
interest
using
maximum
inter-class
variance
method,
pictures
are
preprocessed
account
impacts
staining
inconsistencies
sensitivity
variations
model's
performance.
Ultimately,
we
create
two-phase
continuously
refined
network
(TCRNet)
combining
an
enhanced
refinement
model
with
coarse
built
pyramid
scene
parsing
network.
introduces
auxiliary
term
speed
up
convergence,
implicit
function
reduce
computational
reconstruct
details.
TCRNet
target
successively
aligning
features
without
need
take
cascading
decoder
operations
after
encoder.
Experiments
conducted
digital
images
breast
cancer
osteosarcoma
demonstrate
superior
prediction
accuracy
our
strategy.
Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Авг. 17, 2024
The
second
most
common
type
of
malignant
tumor
worldwide
is
colorectal
cancer.
Histopathology
image
analysis
offers
crucial
data
for
the
clinical
diagnosis
Currently,
deep
learning
techniques
are
applied
to
enhance
cancer
classification
and
localization
in
histopathological
analysis.
Moreover,
traditional
might
loss
integrated
information
while
evaluating
thousands
patches
recovered
from
whole
slide
images
(WSIs).
This
research
proposes
a
novel
detection
network
(CCDNet)
that
combines
coordinate
attention
transformer
with
atrous
convolution.
CCDNet
first
denoises
input
using
Wiener
based
Midpoint
weighted
non-local
means
filter
(WMW-NLM)
guaranteeing
precise
diagnoses
maintain
features.
Also,
convolution
(AConvCAT)
introduced,
which
successfully
advantages
two
networks
classify
tissue
at
various
scales
by
capturing
local
global
information.
Further,
model
Cross-shaped
window
(CrSWin)
tiny
changes
multiple
angles.
proposed
achieved
accuracy
rates
98.61%
98.96%,
on
histological
NCT-CRC-HE-100
K
datasets
correspondingly.
comparison
demonstrates
suggested
framework
performed
better
than
advanced
methods
already
use.
In
hospitals,
clinicians
can
use
verify
diagnosis.
IEEE Transactions on Medical Imaging,
Год журнала:
2024,
Номер
43(9), С. 3149 - 3160
Опубликована: Апрель 12, 2024
Nuclei
classification
provides
valuable
information
for
histopathology
image
analysis.
However,
the
large
variations
in
appearance
of
different
nuclei
types
cause
difficulties
identifying
nuclei.
Most
neural
network
based
methods
are
affected
by
local
receptive
field
convolutions,
and
pay
less
attention
to
spatial
distribution
or
irregular
contour
shape
a
nucleus.
In
this
paper,
we
first
propose
novel
polygon-structure
feature
learning
mechanism
that
transforms
nucleus
into
sequence
points
sampled
order,
employ
recurrent
aggregates
sequential
change
distance
between
key
obtain
learnable
features.
Next,
convert
graph
structure
with
as
nodes,
build
embed
their
representations.
To
capture
correlations
categories
surrounding
tissue
patterns,
further
introduce
edge
features
defined
background
textures
adjacent
Lastly,
integrate
both
polygon
mechanisms
whole
framework
can
extract
intra
inter-nucleus
structural
characteristics
classification.
Experimental
results
show
proposed
achieves
significant
improvements
compared
previous
methods.
Code
data
made
available
via
https://github.com/lhaof/SENC.