Exploring the toxicity of thiamethoxam on aquatic ecosystems: an overarching assessment of biochemical parameters, genotoxicity, fish flesh residues and histological alterations in Nile tilapia
Environmental Pollutants and Bioavailability,
Год журнала:
2025,
Номер
37(1)
Опубликована: Апрель 14, 2025
Язык: Английский
Sub-chronically exposing zebrafish to environmental levels of methomyl induces dysbiosis and dysfunction of the gut microbiota
Environmental Research,
Год журнала:
2024,
Номер
261, С. 119674 - 119674
Опубликована: Июль 23, 2024
Язык: Английский
Sub-Chronically Exposing Zebrafish (Danio Rerio) to Environmental Levels of Methomyl Induces Dysbiosis and Dysfunction of the Gut Microbiota
Опубликована: Янв. 1, 2024
The
widespread
use
of
carbamate
pesticides
has
led
to
numerous
environmental
and
health
concerns,
including
water
contamination
perturbation
endocrine
homeostasis
among
organisms.
However,
there
remains
a
paucity
research
elucidating
the
specific
effects
methomyl
on
gut
microbial
composition
physiological
functions.
This
study
aimed
investigate
intricate
relationship
between
changes
in
zebrafish
bacterial
communities
intestinal
function
after
56
days
sub-chronic
exposure
at
environmentally
relevant
concentrations
(0,
0.05,
0.10,
0.20
mg/L).
Our
findings
reveal
significant
methomyl-induced
morphological
intestines,
characterized
by
villi
shortening
breakage.
Notably,
down-regulated
nutrient
energy
metabolism,
drug
metabolism
0.05−0.10
mg/L,
while
up-regulating
cortisol,
inflammation-related
genes,
apoptotic
markers
mg/L.
These
manifestations
indicate
stress
imposition
disruption
microbiota
equilibrium,
impacting
metabolic
processes
instigating
low-grade
inflammatory
responses
cascades.
Importantly,
significantly
correlated
with
shifts
taxa
abundance,
Shewanella,
Rubrobacter,
Acinetobacter,
Bacillus,
Luteolibacter,
Nocardia,
Defluviimonas,
Bacteroides
genus.
In
summary,
our
underscores
potential
adverse
aquatic
organisms,
emphasizing
necessity
for
further
mitigate
its
repercussions
ecosystem
stability.
Язык: Английский
Toxicity assessment of Oreochromis mossambicus exposed to carbamazepine and selenium: Physiological and genotoxic approach
Environmental Science and Pollution Research,
Год журнала:
2024,
Номер
31(57), С. 65764 - 65777
Опубликована: Ноя. 27, 2024
Язык: Английский
Physiological and biochemical responses of Labeo rohita to neonicotinoids imidacloprid, clothianidin, and their mixture
Fish Physiology and Biochemistry,
Год журнала:
2024,
Номер
51(1), С. 1 - 13
Опубликована: Дек. 2, 2024
Язык: Английский
Assessing spinel zinc ferrite nanoparticles in aquatic ecosystems: toxic threat or beneficial detoxifier for aquatic life?
Aquatic Toxicology,
Год журнала:
2024,
Номер
279, С. 107218 - 107218
Опубликована: Дек. 25, 2024
Язык: Английский
Cytotoxicity of short-term exposure to sublethal dose of the insecticide thiamethoxam to male albino rats
Toxicology and Environmental Health Sciences,
Год журнала:
2024,
Номер
16(2), С. 151 - 160
Опубликована: Апрель 2, 2024
Язык: Английский
Protective effect of Cichorium Intybus ( dandelion) against thiamethoxam induced hepatotoxicity in chicken
Mansoura Veterinary Medical Journal,
Год журнала:
2024,
Номер
25(1)
Опубликована: Янв. 1, 2024
Background
:
Thiamethoxam
(TMX)
is
a
dangerous
neonicotinoid
pesticide
that
induces
liver
damage
in
chickens.
In
this
study,
the
toxicity
of
TMX
chicken
was
examined
along
with
capacity
dandelion
extract
to
alleviate
toxicity.
Methods:
A
total
48
one-day-old,
clinically
healthy,
non-vaccinated
chicks.
Chicks
were
divided
into
four
groups
(12
chicks
per
group):
control
(saline),
TMX,
+
Dandelion
(DAN),
and
DAN
TMX.
The
treatment
orally
administered
at
500
mg/kg
BW
400
BW,
experiment
extended
over
60
days.
Blood
samples
collected
60th
days
post
drug
administration
for
hematological
biochemical
analyses.
addition,
histopathological
examination
performed.
Results:
Oral
chicken-intoxicated
mice
significantly
elevated
levels
Hb,
WBCs,
protein,
albumin
reduced
activities
serum
ALT,
AST,
urea,
uric
acid,
creatinine
compared
those
group.
Furthermore,
decreased
malondialdehyde
content
increased
glutathione
antioxidant
enzyme
activity.
Moreover,
remarkable
decline
mRNA
expression
lL-6
NFKB
recorded
hepatic
tissues
restored
architecture
normal
levels.
Conclusions
addition
dandelions
appears
indicate
healthy
lessens
TMX-induced
chickens
by
reducing
oxidative
stress.
Язык: Английский
Toxic Effects of Imidacloprid, Copper Sulfate, and Their Combinations on Biomolecular and Oxidative/Antioxidant Biomarkers in the Tissues of Oreochromis niloticus
Biological Trace Element Research,
Год журнала:
2024,
Номер
203(1), С. 454 - 466
Опубликована: Окт. 3, 2024
Язык: Английский
Assessing the effects of cadmium on antioxidant enzymes and histological structures in rainbow trout liver and kidney
Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Ноя. 10, 2024
Cadmium
contamination
in
aquatic
environments
poses
severe
risks
to
organisms,
particularly
fish,
where
cadmium
accumulation
tissues
can
lead
compromised
organ
functionality
and
reproductive
issues.
The
present
study
aimed
assess
the
effects
of
(Cd)
exposure
on
key
biomarkers
oxidative
stress,
DNA
damage,
apoptosis,
enzyme
activity
liver
kidney
rainbow
trout
(Oncorhynchus
mykiss).
Specifically,
measured
8-hydroxy-2-deoxyguanosine
(8-OHdG)
levels,
caspase-3
activation,
acetylcholinesterase
(AChE)
activity,
stress
indicators
(ONOO
Язык: Английский