Localization is the key to action: regulatory peculiarities of lncRNAs DOI Creative Commons
Joice de Faria Poloni, Fábio Soares de Oliveira, Bruno César Feltes

и другие.

Frontiers in Genetics, Год журнала: 2024, Номер 15

Опубликована: Дек. 16, 2024

To understand the transcriptomic profile of an individual cell in a multicellular organism, we must comprehend its surrounding environment and cellular space where distinct molecular stimuli responses are located. Contradicting initial perception that RNAs were nonfunctional only few could act chromatin remodeling, over last decades, research has revealed they multifaceted, versatile regulators most processes. Among various RNAs, long non-coding (LncRNAs) regulate multiple biological processes can even impact fate. In this sense, subcellular localization lncRNAs is primary determinant their functions. It affects behavior by limiting potential partner which process it affect. The fine-tuned activity also tissue-specific modulated

Язык: Английский

Localization is the key to action: regulatory peculiarities of lncRNAs DOI Creative Commons
Joice de Faria Poloni, Fábio Soares de Oliveira, Bruno César Feltes

и другие.

Frontiers in Genetics, Год журнала: 2024, Номер 15

Опубликована: Дек. 16, 2024

To understand the transcriptomic profile of an individual cell in a multicellular organism, we must comprehend its surrounding environment and cellular space where distinct molecular stimuli responses are located. Contradicting initial perception that RNAs were nonfunctional only few could act chromatin remodeling, over last decades, research has revealed they multifaceted, versatile regulators most processes. Among various RNAs, long non-coding (LncRNAs) regulate multiple biological processes can even impact fate. In this sense, subcellular localization lncRNAs is primary determinant their functions. It affects behavior by limiting potential partner which process it affect. The fine-tuned activity also tissue-specific modulated

Язык: Английский

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